Table 3.

DPWG (2017) Recommendations for Abacavir based on HLA-B Genotype

GenotypeRecommendation
HLA-B*57:01-positiveAbacavir is contraindicated for HLA-B*57:01-positive patients. Advise the prescriber to prescribe an alternative according to the current guidelines.

Please see 2017 Summary of recommendations from the Dutch Pharmacogenetics Working Group (DPWG) of the Royal Dutch Association for the Advancement of Pharmacy (KNMP) for more information from DPWG. Table adapted from (5).

From: Abacavir Therapy and HLA-B*57:01 Genotype

Cover of Medical Genetics Summaries
Medical Genetics Summaries [Internet].
Pratt VM, Scott SA, Pirmohamed M, et al., editors.
Copyright Notice

All Medical Genetics Summaries content, except where otherwise noted, is licensed under a Creative Commons Attribution 4.0 International (CC BY 4.0) license which permits copying, distribution, and adaptation of the work, provided the original work is properly cited and any changes from the original work are properly indicated. Any altered, transformed, or adapted form of the work may only be distributed under the same or similar license to this one.

NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health.