Distinguishing Characteristics of Mononeuropathies, Entrapment Syndromes and Distal Symmetrical Polyneuropathy
| Feature | Mononeuropathy | Entrapment syndrome | Neuropathy |
|---|---|---|---|
| Onset | Sudden | Gradual | Gradual |
| Pattern | Single nerve but may be multiple | Single nerve exposed to trauma | Distal symmetrical poly neuropathy |
| Nerves involved | CN III, VI, VII, ulnar, median, peroneal | Median, ulnar, peroneal, medial and lateral plantar | Mixed, Motor, Sensory, Autonomic |
| Natural history | Resolves spontaneously | Progressive | Progressive |
| Treatment | Symptomatic | Rest, splints, local steroids, diuretics, surgery | Tight Glycemic control, Pregabalin, Duloxetine, Antioxidants, “Nutrinerve”, Research Drugs. |
| Distribution of Sensory loss | Area supplied by the nerve | Area supplied beyond the site of entrapment | Distal and symmetrical. “Glove and Stocking” distribution. |
CN, cranial nerves; NSAIDs, non-steroidal anti-inflammatory drugs
From: Diabetic Neuropathies
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