Splign

The Splign service is no longer available. Please try Magic-BLAST a standalone BLAST-based splice-aware alignment tool.

Splign is a utility for computing cDNA-to-Genomic, or spliced sequence alignments. At the heart of the program is a compartmentization algorithm which identifies possible gene duplications, and a refined alignment algorithm recognizing introns and splice signals.

References:

Y.Kapustin, A.Souvorov, T.Tatusova and D.Lipman. Splign: algorithms for computing spliced alignments with identification of paralogs. Biology Direct, May 2008.
Y.Kapustin, A.Souvorov and T.Tatusova. Splign - a Hybrid Approach To Spliced Alignments. RECOMB 2004 - Currents in Computational Molecular Biology. p.741.

Help: for questions, comments, or bug reporting, please visit NCBI Support Center