2BU5: crystal structures of human pyruvate dehydrogenase kinase 2 containing physiological and synthetic ligands

PDB ID: 2BU5Download
MMDB ID: 37573
PDB Deposition Date: 2005/6/8
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 2.35  Å
Source Organism:
Similar Structures:
Biological Unit for 2BU5: dimeric; determined by author and by software (PQS)
Molecular Components in 2BU5
Label Count Molecule
Proteins (2 molecules)
2
Pyruvate Dehydrogenase Kinase Isoenzyme 2
(Gene symbol: PDK2)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
2
4-({(2R,5S)-2,5-DIMETHYL-4-[(2R)-3,3,3-TRIFLUORO-2-HYDROXY-2-METHYLPROPANOYL]PIPERAZIN-1-YL}CARBONYL)BENZONITRILE4-({(2R,5S)-2,5-DIMETHYL-4-[(2R)-3,3,3-TRIFLUORO-2-HYDROXY-2-METHYLPROPANOYL]PIPERAZIN-1-YL}CARBONYL)BENZONITRILE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303