3QPP: Structure of PDE10-inhibitor complex

PDB ID: 3QPPDownload
MMDB ID: 91899
PDB Deposition Date: 2011/2/14
Updated in MMDB: 2011/07
Experimental Method:
x-ray diffraction
Resolution: 1.8  Å
Source Organism:
Similar Structures:
Biological Unit for 3QPP: monomeric; determined by author
Molecular Components in 3QPP
Label Count Molecule
Protein (1 molecule)
1
Camp and Camp-inhibited Cgmp 3',5'-cyclic Phosphodiesterase 10A
(Gene symbol: Pde10a)
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
1
ZINC IONZINC ION
2
1
MAGNESIUM IONMAGNESIUM ION
3
1
SULFATE IONSULFATE ION
4
2
DIMETHYL SULFOXIDEDIMETHYL SULFOXIDE
5
1
7-methoxy-4-[(3S)-3-phenylpiperidin-1-yl]-6-[2-(quinolin-2-yl)ethoxy]quinazoline7-methoxy-4-[(3S)-3-phenylpiperidin-1-yl]-6-[2-(quinolin-2-yl)ethoxy]quinazoline
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303