3KF4: Structural analysis of DFG-in and DFG-out dual Src-Abl inhibitors sharing a common vinyl purine template

PDB ID: 3KF4Download
MMDB ID: 78946
PDB Deposition Date: 2009/10/27
Updated in MMDB: 2009/12
Experimental Method:
x-ray diffraction
Resolution: 1.9  Å
Source Organism:
Similar Structures:
Biological Unit for 3KF4: monomeric; determined by author and by software (PISA)
Molecular Components in 3KF4
Label Count Molecule
Protein (1 molecule)
1
Tyrosine-protein Kinase Abl1
(Gene symbol: Abl1)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
N-[4-(dimethylphosphoryl)phenyl]-9-[(E)-2-(5-methyl-1H-indazol-4-yl)ethenyl]-9H-purin-6-amineN-[4-(dimethylphosphoryl)phenyl]-9-[(E)-2-(5-methyl-1H-indazol-4-yl)ethenyl]-9H-purin-6-amine
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303