8B6F: Cryo-EM structure of NADH:ubiquinone oxidoreductase (complex-I) from respiratory supercomplex of Tetrahymena thermophila

PDB ID: 8B6FDownload
MMDB ID: 228427
PDB Deposition Date: 2022
Updated in MMDB: 2024/11
Experimental Method:
electron microscopy
Resolution: 2.8  Å
Source Organism:
Similar Structures:
Biological Unit for 8B6F: 69-meric; determined by author
Molecular Components in 8B6F
Label Count Molecule
Proteins (69 molecules)
1
Lipid-a-disaccharide Synthase
Molecule annotation
1
Nad-dependent Epimerase/dehydratase Family Protein
Molecule annotation
1
Dnaj Domain Protein
Molecule annotation
1
Acyl-coa Synthetase (Amp-forming)/amp-acid Ligase II
Molecule annotation
1
Rnase III Domain-containing Protein
Molecule annotation
1
37S Ribosomal Protein S25, Mitochondrial
Molecule annotation
1
Transmembrane Protein, Putative
Molecule annotation
1
Cx9c Domain-containing Protein
Molecule annotation
1
Ndutt15
Molecule annotation
1
Transmembrane Protein, Putative
Molecule annotation
1
Nadh Dehydrogenase Subunit 5
Molecule annotation
1
Nadh-ubiquinone Oxidoreductase 75 KDA Subunit
Molecule annotation
1
Nadh-ubiquinone Oxidoreductase Chain 4
Molecule annotation
1
Nadh Dehydrogenase [ubiquinone] Flavoprotein 1, Mitochondrial
Molecule annotation
1
Nadh Dehydrogenase Subunit 7
Molecule annotation
1
Ymf65
Molecule annotation
1
Transcription Factor Apfi Protein, Putative
Molecule annotation
1
Nadh-ubiquinone Oxidoreductase Chain 1
Molecule annotation
1
Nadh-ubiquinone Oxidoreductase 24 KDA Subunit
Molecule annotation
1
Ymf62
Molecule annotation
1
Gamma-carbonic Anhydrase
Molecule annotation
1
Nadh-ubiquinone Oxidoreductase 1, Chain, Putative
Molecule annotation
1
Gamma-carbonic Anhydrase
Molecule annotation
1
ETC Complex I Subunit Motif Protein
Molecule annotation
1
Nadh Dehydrogenase Subunit 9
Molecule annotation
1
Nadh Dehydrogenase [ubiquinone] 1 Alpha Subcomplex Subunit 12
Molecule annotation
1
Nadh Dehydrogenase [ubiquinone] 1 Alpha Subcomplex Subunit 10, Mitochondrial
Molecule annotation
1
Nadh Dehydrogenase [ubiquinone] Iron-sulfur Protein 4, Mitochondrial
Molecule annotation
1
Nadh Dehydrogenase, Putative
Molecule annotation
1
Nadh Dehydrogenase Subunit 10
Molecule annotation
1
Nadh-ubiquinone Oxidoreductase Complex I, 21 KDA Subunit
Molecule annotation
1
Acyl Carrier Protein
Molecule annotation
1
Acyl Carrier Protein
Molecule annotation
1
Nadh-ubiquinone Oxidoreductase Chain 3
Molecule annotation
1
Ymf58
Molecule annotation
1
Ribosomal Protein L51/s25/ci-b8 Domain Protein
Molecule annotation
1
Transmembrane Protein, Putative
Molecule annotation
1
ATP Synthase Subunit E, Mitochondrial
Molecule annotation
1
Gram Domain Protein
Molecule annotation
1
Transmembrane Protein, Putative
Molecule annotation
1
Transmembrane Protein, Putative
Molecule annotation
1
Transmembrane Protein, Putative
Molecule annotation
1
Nd1b
Molecule annotation
1
Transmembrane Protein
Molecule annotation
1
Transmembrane Protein, Putative
Molecule annotation
1
Ndub8
Molecule annotation
1
Transmembrane Protein, Putative
Molecule annotation
1
Nduph2
Molecule annotation
1
Ndub10
Molecule annotation
1
Ndua13
Molecule annotation
1
Nadh Dehydrogenase Subunit 2
Molecule annotation
1
2 Iron, 2 Sulfur Cluster-binding Protein
Molecule annotation
1
Thioredoxin
Molecule annotation
1
COX Assembly Mitochondrial Protein
Molecule annotation
1
Transmembrane Protein, Putative
Molecule annotation
1
Transmembrane Protein, Putative
Molecule annotation
1
PH Domain-containing Protein
Molecule annotation
1
Nadh Dehydrogenase [ubiquinone] 1 Alpha Subcomplex Subunit 8
Molecule annotation
1
Ndub6
Molecule annotation
1
Nadh Dehydrogenase [ubiquinone] 1 Beta Subcomplex Subunit 4
Molecule annotation
1
Zinc-finger Protein
Molecule annotation
1
Ndub4
Molecule annotation
1
Ndub15
Molecule annotation
1
Ndutt16
Molecule annotation
1
Ndutt17
Molecule annotation
1
Chch Domain-containing Protein
Molecule annotation
1
Transmembrane Protein, Putative
Molecule annotation
1
Ymf57
Molecule annotation
1
Complex I-mnll
Molecule annotation
Chemicals and Non-standard biopolymers (77 molecules)
22
CARDIOLIPIN (Link to PubChem not yet available)CARDIOLIPIN
1
URIDINE-5'-DIPHOSPHATE (Link to PubChem not yet available)URIDINE-5'-DIPHOSPHATE
2
MAGNESIUM ION (Link to PubChem not yet available)MAGNESIUM ION
27
1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE (Link to PubChem not yet available)1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE
1
NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE (Link to PubChem not yet available)NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
6
1,2-Distearoyl-sn-glycerophosphoethanolamine (Link to PubChem not yet available)1,2-Distearoyl-sn-glycerophosphoethanolamine
4
2-(HEXADECANOYLOXY)-1-[(PHOSPHONOOXY)METHYL]ETHYL HEXADECANOATE (Link to PubChem not yet available)2-(HEXADECANOYLOXY)-1-[(PHOSPHONOOXY)METHYL]ETHYL HEXADECANOATE
2
ADENOSINE-5'-DIPHOSPHATE (Link to PubChem not yet available)ADENOSINE-5'-DIPHOSPHATE
3
FE2/S2 (INORGANIC) CLUSTER (Link to PubChem not yet available)FE2/S2 (INORGANIC) CLUSTER
6
IRON/SULFUR CLUSTER (Link to PubChem not yet available)IRON/SULFUR CLUSTER
1
FLAVIN MONONUCLEOTIDE (Link to PubChem not yet available)FLAVIN MONONUCLEOTIDE
1
S-[2-({N-[(2R)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] dodecanethioate (Link to PubChem not yet available)S-[2-({N-[(2R)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] dodecanethioate
1
ZINC ION (Link to PubChem not yet available)ZINC ION
* Click molecule labels to explore molecular sequence information.

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