7DHR: Cryo-EM structure of the full agonist isoprenaline-bound beta2 adrenergic receptor-Gs protein complex

PDB ID: 7DHRDownload
MMDB ID: 196619
PDB Deposition Date: 2020
Updated in MMDB: 2024/11
Experimental Method:
electron microscopy
Resolution: 3.8  Å
Source Organism:
Bos taurus▼
Similar Structures:
Biological Unit for 7DHR: pentameric; determined by author
Molecular Components in 7DHR
Label Count Molecule
Proteins (5 molecules)
1
Guanine Nucleotide-binding Protein G(s) Subunit Alpha Isoforms Short
Molecule annotation
1
Guanine Nucleotide-binding Protein G(i)/g(s)/g(t) Subunit Beta-1
Molecule annotation
1
Guanine Nucleotide-binding Protein G(i)/g(s)/g(o) Subunit Gamma-2
Molecule annotation
1
Nb35 Nanobody
Molecule annotation
1
Beta-2 Adrenergic Receptor
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
ISOPRENALINE (Link to PubChem not yet available)ISOPRENALINE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303