6SMN: A. thaliana serine hydroxymethyltransferase isoform 2 (AtSHMT2) in complex with methotrexate

PDB ID: 6SMNDownload
MMDB ID: 182950
PDB Deposition Date: 2019/8/22
Updated in MMDB: 2024/01
Experimental Method:
x-ray diffraction
Resolution: 1.63  Å
Source Organism:
Similar Structures:
Biological Unit for 6SMN: tetrameric; determined by author and by software (PISA)
Molecular Components in 6SMN
Label Count Molecule
Proteins (4 molecules)
3
Serine Hydroxymethyltransferase 2, Mitochondrial
(Gene symbol: SHM2)
Molecule annotation
1
Serine Hydroxymethyltransferase 2, Mitochondrial
(Gene symbol: SHM2)
Molecule annotation
Chemicals and Non-standard biopolymers (56 molecules)
1
3
[3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL]-SERINE[3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL]-SERINE
2
48
1,2-ETHANEDIOL1,2-ETHANEDIOL
3
4
METHOTREXATEMETHOTREXATE
4
1
SERINESERINE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303