2ZMD: Crystal structure of human Mps1 catalytic domain T686A mutant in complex with SP600125 inhibitor

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PDB ID: 2ZMDDownload
MMDB ID: 64436
PDB Deposition Date: 2008/4/16
Updated in MMDB: 2023/11
Experimental Method:
x-ray diffraction
Resolution: 2.88  Å
Source Organism:
Similar Structures:
Biological Unit for 2ZMD: monomeric; determined by author
Molecular Graphic ?
2ZMD: Crystal structure of human Mps1 catalytic domain T686A mutant in complex with SP600125 inhibitor
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Interactions?
AA: Dual specificity protein kinase TTK1537: 2,6-DIHYDROANTHRA/1,9-CD/PYRAZOL-6-ONE27PE: 2-(2-(2-(2-(2-(2-ETHOXYETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHANOL
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Data Set:
Molecular Components in 2ZMD
Label Count Molecule
Protein (1 molecule)
1
Dual Specificity Protein Kinase TTK
(Gene symbol: TTK)
1 Protein
SS Diagram
3D Domains
175150225300390390 residues, click to see VAST similar structures.helix 95-111helix 154-174helix 247-261helix 273-281helix 295-305helix 314-321strand 50-54strand 55-60strand 61-67strand 69-77strand 81-90strand 120-128strand 129-136strand 139-142strand 185-190strand 191-196Domain 1 (1-137): click to see VAST similar structures1Domain 2 (138-221): click to see VAST similar structures2Domain 3 (222-390): click to see VAST similar structures3
Chemicals and Non-standard biopolymers (2 molecules)
1
1
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