6SMR: A. thaliana serine hydroxymethyltransferase isoform 4 (AtSHMT4) in complex with methotrexate

PDB ID: 6SMRDownload
MMDB ID: 182951
PDB Deposition Date: 2019/8/22
Updated in MMDB: 2024/01
Experimental Method:
x-ray diffraction
Resolution: 2.12  Å
Source Organism:
Similar Structures:
Biological Unit for 6SMR: tetrameric; determined by author and by software (PISA)
Molecular Components in 6SMR
Label Count Molecule
Proteins (4 molecules)
4
Serine Hydroxymethyltransferase 4
(Gene symbol: SHM4)
Molecule annotation
Chemicals and Non-standard biopolymers (17 molecules)
1
4
[3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL]-SERINE[3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL]-SERINE
2
9
1,2-ETHANEDIOL1,2-ETHANEDIOL
3
3
METHOTREXATEMETHOTREXATE
4
1
2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303