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Application of Off-Rate Screening in the Identification of Novel Pan-Isoform Inhibitors of Pyruvate Dehydrogenase Kinase[TRANSFERASE]
View in iCn3D Similar StructuresPubMedProteinsConserved DomainsPubChem Compound
Crystal structure of pyruvate dehydrogenase kinase isoform 2 in complex with inhibitor PS35[Transferase/Transferase Inhibitor]
Crystal structure of pyruvate dehydrogenase kinase isoform 2 in complex with inhibitor PS46[Transferase/Transferase Inhibitor]
VER-246608, a novel pan-isoform ATP competitive inhibitor of pyruvate dehydrogenase kinase, disrupts Warburg metabolism and induces context- dependent cytostasis in cancer cells[TRANSFERASE]
Crystal structure of pyruvate dehydrogenase kinase isoform 2 in complex with inhibitor PS10[TRANSFERASE]
Crystal structure of pyruvate dehydrogenase kinase isoform 2 in complex with inhibitor PS8[Transferase/Transferase Inhibitor]
Crystal structure of pyruvate dehydrogenase kinase isoform 2 in complex with inhibitor PS2[Transferase/Transferase Inhibitor]
Crystal structure of pyruvate dehydrogenase kinase isoform 2 in complex with inhibitor PA7[Transferase/Transferase Inhibitor]
Crystal structure of pyruvate dehydrogenase kinase isoform 2 in complex with inhibitor PA1[Transferase/Transferase Inhibitor]
crystal structures of human pyruvate dehydrogenase kinase 2 containing physiological and synthetic ligands[TRANSFERASE]
View in iCn3D Similar StructuresPubMedProteinsConserved Domains
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