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Optimization of spirocyclic proline tryptophanhydroxylase-1 inhibitors[OXIDOREDUCTASE/OXIDOREDUCTASE inhibitor]
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Tryptophan 5-hydroxylase in complex with inhibitor (3~{S})-8-[2-azanyl-6-[(1~{R})-1-(4-chloranyl-2-phenyl-phenyl)-2,2,2-tris(fluoranyl)ethoxy]pyrimidin-4-yl]-2,8-diazaspiro[4.5]decane-3-carboxylic aci...
Discovery of acyl guanidine tryptophan hydroxylase-1 inhibitors[OXIDOREDUCTASE/INHIBITOR]
Crystal structure of human tryoptophan hydroxylase type 1 with LP-534193[OXIDOREDUCTASE]
Crystal structure of human tryoptophan hydroxylase type 1 with bound LP-533401 and Fe[OXIDOREDUCTASE]
Crystal structure of human tryptophan hydroxylase type 1 with bound LP-521834 and FE[OXIDOREDUCTASE]
Crystal structure of human tryptophan hydroxylase with bound 7,8-dihydro-L-biopterin cofactor and Fe(III)[OXIDOREDUCTASE]
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