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The crystal structue of PDE10A complexed with 2d[HYDROLASE]
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The crystal structue of PDE10A complexed with 1i[HYDROLASE]
Crystal structure of PDE10A in complex with a triazolopyrimidine inhibitor[HYDROLASE]
Crystal structure of PDE10 in complex with inhibitor 2b[HYDROLASE/INHIBITOR]
Crystal structure of PDE10 in complex with inhibitor AF-399/14387019[HYDROLASE/INHIBITOR]
Crystal structure of PDE10A in complex with 7-(4-chlorophenyl)-2-methylpyrazolo[1,5-a]pyrimidine[HYDROLASE/HYDROLASE INHIBITOR]
Crystal structure of PDE10A in complex with 2-methyl-5-[2-([1,2,4]triazolo[1,5-a]pyrimidin-2-yl)et hyl]pyrazolo[1,5-a]pyrimidin-7-ol[HYDROLASE/HYDROLASE INHIBITOR]
Crystal structure of human PDE10A in complex with inhibitor 16d[Hydrolase/Hydrolase Inhibitor]
PDE10a with imidazopyrazine inhibitor[HYDROLASE/HYDROLASE INHIBITOR]
CRYSTAL STRUCTURE OF HUMAN PHOSPHODIESTERASE 10 IN COMPLEX WITH C2(=NN(c1cccc(c1)OC(F)(F)F)C=CC2=O)c3ccnn3c4ccccc4, micromolar IC50=0.019462[HYDROLASE]
CRYSTAL STRUCTURE OF HUMAN PHOSPHODIESTERASE 10 IN COMPLEX WITH c2(c(n1nc(nc1c(c2)C)CCc3nc(nn3C)N4CCCC4)C)Cl, micromolar IC50=0.000279[HYDROLASE]
CRYSTAL STRUCTURE OF HUMAN PHOSPHODIESTERASE 10 IN COMPLEX WITH n4c(C)n1c(nc(n1)CCc2nc(nn2C)N3CCCC3)c(c4)CC, micromolar IC50=0.0037753[HYDROLASE]
CRYSTAL STRUCTURE OF HUMAN PHOSPHODIESTERASE 10 IN COMPLEX WITH c1(c(nc([nH]1)Cl)c2ccccc2)C4=NN(c3cccc(c3)OC(F)(F)F)C=CC4=O, micromolar IC50=0.029618[HYDROLASE]
PDE10 complexed with N-[(1-methylpyrazol-4-yl)methyl]-5-[[(1S,2S)-2-(2-pyridyl)cyclopropyl]methoxy]pyrazolo[1,5-a]pyrimidin-7-amine[HYDROLASE/HYDROLASE INHIBITOR]
PDE10 complexed with 5-chloro-N-[(2,4-dimethylthiazol-5-yl)methyl]pyrazolo[1,5-a]pyrimidin-7-amine[HYDROLASE/HYDROLASE INHIBITOR]
PDE10 complexed with6-chloro-N-[(2,4-dimethylthiazol-5-yl)methyl]-5-methyl-2-[2-(2-pyridyl)ethoxy]pyrimidin-4-amine[hydrolase/hydrolase inhibitor]
Crystal structure of the catalytic domain of PDE10A complexed with highly potent and brain-penetrant PDE10A Inhibitor with 2-oxindole scaffold[HYDROLASE/HYDROLASE INHIBITOR]
Crystal structure of the catalytic domain of PDE10A complexed with 1-(2-fluoro-4-(2-oxo-1,3-oxazolidin-3-yl)phenyl)-5-methoxy-3-(1-phenyl-1H-pyrazol-5-yl)pyridazin-4(1H)-one[HYDROLASE/HYDROLASE INHIBI...
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