2FXR: human beta tryptase II complexed with activated ketone inhibitor CRA-29382

PDB ID: 2FXRDownload
MMDB ID: 37841
PDB Deposition Date: 2006/2/6
Updated in MMDB: 2024/10
Experimental Method:
x-ray diffraction
Resolution: 2.5  Å
Source Organism:
Similar Structures:
Biological Unit for 2FXR: tetrameric; determined by author and by software (PISA)
Molecular Components in 2FXR
Label Count Molecule
Proteins (4 molecules)
4
Tryptase Beta-2
(Gene symbol: TPSAB1)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
4
ALLYL {(1S)-1-[(5-{4-[(2,3-DIHYDRO-1H-INDEN-2-YLAMINO)CARBONYL]BENZYL}-1,2,4-OXADIAZOL-3-YL)CARBONYL]-3-PYRROLIDIN-3-YLPROPYL}CARBAMATEALLYL {(1S)-1-[(5-{4-[(2,3-DIHYDRO-1H-INDEN-2-YLAMINO)CARBONYL]BENZYL}-1,2,4-OXADIAZOL-3-YL)CARBONYL]-3-PYRROLIDIN-3-YLPROPYL}CARBAMATE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303