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Factor XIa in complex with the inhibitor 4-{2-[(1S)-1-({[trans-4-(aminomethyl)cyclohexyl]carbonyl}amino)-2-phenylethyl]-1H-imidazol-4-yl}benzamide[Hydrolase/Hydrolase Inhibitor]
View in iCn3D Similar StructuresPubMedProteinsConserved DomainsPubChem Compound
Crystal Structure of the Catalytic Domain of Coagulation Factor XI in Complex with 2-(5-Amino-6-oxo-2-m-tolyl-6H-pyrimidin-1-yl)-N-[4-guanidino-1-(thiazole-2-carbonyl)-butyl]-acetamide[HYDROLASE]
View in iCn3D Similar StructuresProteinsConserved DomainsPubChem Compound
Crystal Structure of the Catalytic Domain of Coagulation Factor XI in Complex with N-[4-Guanidino-1-(thiazole-2-carbonyl)-butyl]-2-{6-oxo-5-[(quinolin-8-ylmethyl)-amino]-2-m-tolyl-6H-pyrimidin-1-yl}-a...
Crystal Structure At 2.9 Angstroms Resolution Of Human Plasma Coagulation Factor Xi Zymogen[Hydrolase, EC: 3.4.21.27]
View in iCn3D Similar StructuresPubMedProteinsConserved Domains
Solution Structure of the A4 Domain of Blood Coagulation Factor XI[HYDROLASE]
FXI Apple 4 domain loop-out conformation[HYDROLASE]
Crystal structure of Factor XIa in complex with Clavatadine A[HYDROLASE]
Factor XIa in complex with a clorophenyl-tetrazole inhibitor[Hydrolase/Hydrolase inhibitor]
Benzothiazinone inhibitor in complex with FXIa[Hydrolase/Hydrolase Inhibitor]
Factor XIA in complex with the inhibitor 3'-[(2S,4R)-6-carbamimidoyl-4-methyl-4-phenyl-1,2,3,4-tetrahydroquinolin-2-yl]-4-carbamoyl-5'-[(3-methylbutanoyl)amino]biphenyl-2-carboxylic acid[HYDROLASE/HYD...
Factor XIa in complex with the inhibitor 5-aminocarbonyl-2-[3-[(2s,4r)-6-carbamimidoyl-4-methyl-4-phenyl-2,3-dihydro-1h-quinolin-2-yl]phenyl]benzoic acid[hydrolase/hydrolase inhibitor]
Crystal Structure of the Catalytic Domain of Coagulation Factor XI in Complex with 2-(5-Benzylamino-2-methylsulfanyl-6-oxo-6H-pyrimidin-1-yl)-N-[4-guanidino-1-(thiazole-2-carbonyl)-butyl]-acetamide[HY...
Factor XIa in complex with the inhibitor (2S)-6-amino-N-{(1S)-1-[4-(3-amino-2H-indazol-6-yl)-5-chloro-1H-imidazol-2-yl]-2-phenylethyl}-2-ethylhexanamide[Hydrolase/Hydrolase Inhibitor]
FACTOR XIA IN COMPLEX WITH THE INHIBITOR trans-N-{(1S)-1-[4-(3-amino-2H-indazol-6-yl)pyridin-2-yl]-2-phenylethyl}-4-(aminomethyl)cyclohexanecarboxamide[hydrolase/hydrolase inhibitor]
Creating novel F1 inhibitors through fragment based lead generation and structure aided drug design[HYDROLASE]
Creating Novel F1 Inhibitors Through Fragment Based Lead Generation And Structure Aided Drug Design[Hydrolase, EC: 3.4.21.27]
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