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1.

rs1491335559 has merged into rs373647297 [Homo sapiens]
    Variant type:
    DELINS
    Alleles:
    TTTTTTTTTTTTTT>-,TTT,TTTT,TTTTT,TTTTTT,TTTTTTT,TTTTTTTT,TTTTTTTTT,TTTTTTTTTT,TTTTTTTTTTT,TTTTTTTTTTTT,TTTTTTTTTTTTT,TTTTTTTTTTTTTTT,TTTTTTTTTTTTTTTT,TTTTTTTTTTTTTTTTT,TTTTTTTTTTTTTTTTTT,TTTTTTTTTTTTTTTTTTT,TTTTTTTTTTTTTTTTTTTT,TTTTTTTTTTTTTTTTTTTTT,TTTTTTTTTTTTTTTTTTTTTT,TTTTTTTTTTTTTTTTTTTTTTT,TTTTTTTTTTTTTTTTTTTTTTTT,TTTTTTTTTTTTTTTTTTTTTTTTT,TTTTTTTTTTTTTTTTTTTTTTTTTT,TTTTTTTTTTTTTTTTTTTTTTTTTTT,TTTTTTTTTTTTTTTTTTTTTTTTTTTT,TTTTTTTTTTTTTTTTTTTTTTTTTTTTT,TTTTTTTTTTTTTTTTTTTTTTTTTTTTTT,TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT,TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT [Show Flanks]
    Chromosome:
    14:50637676 (GRCh38)
    14:51104394 (GRCh37)
    Canonical SPDI:
    NC_000014.9:50637664:TTTTTTTTTTTTTTTTTTTTTTTTT:TTTTTTTTTTT,NC_000014.9:50637664:TTTTTTTTTTTTTTTTTTTTTTTTT:TTTTTTTTTTTTTT,NC_000014.9:50637664:TTTTTTTTTTTTTTTTTTTTTTTTT:TTTTTTTTTTTTTTT,NC_000014.9:50637664:TTTTTTTTTTTTTTTTTTTTTTTTT:TTTTTTTTTTTTTTTT,NC_000014.9:50637664:TTTTTTTTTTTTTTTTTTTTTTTTT:TTTTTTTTTTTTTTTTT,NC_000014.9:50637664:TTTTTTTTTTTTTTTTTTTTTTTTT:TTTTTTTTTTTTTTTTTT,NC_000014.9:50637664:TTTTTTTTTTTTTTTTTTTTTTTTT:TTTTTTTTTTTTTTTTTTT,NC_000014.9:50637664:TTTTTTTTTTTTTTTTTTTTTTTTT:TTTTTTTTTTTTTTTTTTTT,NC_000014.9:50637664:TTTTTTTTTTTTTTTTTTTTTTTTT:TTTTTTTTTTTTTTTTTTTTT,NC_000014.9:50637664:TTTTTTTTTTTTTTTTTTTTTTTTT:TTTTTTTTTTTTTTTTTTTTTT,NC_000014.9:50637664:TTTTTTTTTTTTTTTTTTTTTTTTT:TTTTTTTTTTTTTTTTTTTTTTT,NC_000014.9:50637664:TTTTTTTTTTTTTTTTTTTTTTTTT:TTTTTTTTTTTTTTTTTTTTTTTT,NC_000014.9:50637664:TTTTTTTTTTTTTTTTTTTTTTTTT:TTTTTTTTTTTTTTTTTTTTTTTTTT,NC_000014.9:50637664:TTTTTTTTTTTTTTTTTTTTTTTTT:TTTTTTTTTTTTTTTTTTTTTTTTTTT,NC_000014.9:50637664:TTTTTTTTTTTTTTTTTTTTTTTTT:TTTTTTTTTTTTTTTTTTTTTTTTTTTT,NC_000014.9:50637664:TTTTTTTTTTTTTTTTTTTTTTTTT:TTTTTTTTTTTTTTTTTTTTTTTTTTTTT,NC_000014.9:50637664:TTTTTTTTTTTTTTTTTTTTTTTTT:TTTTTTTTTTTTTTTTTTTTTTTTTTTTTT,NC_000014.9:50637664:TTTTTTTTTTTTTTTTTTTTTTTTT:TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT,NC_000014.9:50637664:TTTTTTTTTTTTTTTTTTTTTTTTT:TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT,NC_000014.9:50637664:TTTTTTTTTTTTTTTTTTTTTTTTT:TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT,NC_000014.9:50637664:TTTTTTTTTTTTTTTTTTTTTTTTT:TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT,NC_000014.9:50637664:TTTTTTTTTTTTTTTTTTTTTTTTT:TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT,NC_000014.9:50637664:TTTTTTTTTTTTTTTTTTTTTTTTT:TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT,NC_000014.9:50637664:TTTTTTTTTTTTTTTTTTTTTTTTT:TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT,NC_000014.9:50637664:TTTTTTTTTTTTTTTTTTTTTTTTT:TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT,NC_000014.9:50637664:TTTTTTTTTTTTTTTTTTTTTTTTT:TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT,NC_000014.9:50637664:TTTTTTTTTTTTTTTTTTTTTTTTT:TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT,NC_000014.9:50637664:TTTTTTTTTTTTTTTTTTTTTTTTT:TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT,NC_000014.9:50637664:TTTTTTTTTTTTTTTTTTTTTTTTT:TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT,NC_000014.9:50637664:TTTTTTTTTTTTTTTTTTTTTTTTT:TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
    Gene:
    SAV1 (Varview)
    Functional Consequence:
    intron_variant,genic_downstream_transcript_variant
    Validated:
    by frequency,by alfa,by cluster
    MAF:
    TTTTTTTTTTT=0./0 (ALFA)
    TTTTTTTTT=0.0065/3 (NorthernSweden)
    HGVS:
    NC_000014.9:g.50637676_50637689del, NC_000014.9:g.50637679_50637689del, NC_000014.9:g.50637680_50637689del, NC_000014.9:g.50637681_50637689del, NC_000014.9:g.50637682_50637689del, NC_000014.9:g.50637683_50637689del, NC_000014.9:g.50637684_50637689del, NC_000014.9:g.50637685_50637689del, NC_000014.9:g.50637686_50637689del, NC_000014.9:g.50637687_50637689del, NC_000014.9:g.50637688_50637689del, NC_000014.9:g.50637689del, NC_000014.9:g.50637689dup, NC_000014.9:g.50637688_50637689dup, NC_000014.9:g.50637687_50637689dup, NC_000014.9:g.50637686_50637689dup, NC_000014.9:g.50637685_50637689dup, NC_000014.9:g.50637684_50637689dup, NC_000014.9:g.50637683_50637689dup, NC_000014.9:g.50637682_50637689dup, NC_000014.9:g.50637681_50637689dup, NC_000014.9:g.50637680_50637689dup, NC_000014.9:g.50637679_50637689dup, NC_000014.9:g.50637678_50637689dup, NC_000014.9:g.50637677_50637689dup, NC_000014.9:g.50637676_50637689dup, NC_000014.9:g.50637675_50637689dup, NC_000014.9:g.50637674_50637689dup, NC_000014.9:g.50637673_50637689dup, NC_000014.9:g.50637689_50637690insTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT, NC_000014.8:g.51104394_51104407del, NC_000014.8:g.51104397_51104407del, NC_000014.8:g.51104398_51104407del, NC_000014.8:g.51104399_51104407del, NC_000014.8:g.51104400_51104407del, NC_000014.8:g.51104401_51104407del, NC_000014.8:g.51104402_51104407del, NC_000014.8:g.51104403_51104407del, NC_000014.8:g.51104404_51104407del, NC_000014.8:g.51104405_51104407del, NC_000014.8:g.51104406_51104407del, NC_000014.8:g.51104407del, NC_000014.8:g.51104407dup, NC_000014.8:g.51104406_51104407dup, NC_000014.8:g.51104405_51104407dup, NC_000014.8:g.51104404_51104407dup, NC_000014.8:g.51104403_51104407dup, NC_000014.8:g.51104402_51104407dup, NC_000014.8:g.51104401_51104407dup, NC_000014.8:g.51104400_51104407dup, NC_000014.8:g.51104399_51104407dup, NC_000014.8:g.51104398_51104407dup, NC_000014.8:g.51104397_51104407dup, NC_000014.8:g.51104396_51104407dup, NC_000014.8:g.51104395_51104407dup, NC_000014.8:g.51104394_51104407dup, NC_000014.8:g.51104393_51104407dup, NC_000014.8:g.51104392_51104407dup, NC_000014.8:g.51104391_51104407dup, NC_000014.8:g.51104407_51104408insTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT, NG_045326.1:g.404_417del, NG_045326.1:g.407_417del, NG_045326.1:g.408_417del, NG_045326.1:g.409_417del, NG_045326.1:g.410_417del, NG_045326.1:g.411_417del, NG_045326.1:g.412_417del, NG_045326.1:g.413_417del, NG_045326.1:g.414_417del, NG_045326.1:g.415_417del, NG_045326.1:g.416_417del, NG_045326.1:g.417del, NG_045326.1:g.417dup, NG_045326.1:g.416_417dup, NG_045326.1:g.415_417dup, NG_045326.1:g.414_417dup, NG_045326.1:g.413_417dup, NG_045326.1:g.412_417dup, NG_045326.1:g.411_417dup, NG_045326.1:g.410_417dup, NG_045326.1:g.409_417dup, NG_045326.1:g.408_417dup, NG_045326.1:g.407_417dup, NG_045326.1:g.406_417dup, NG_045326.1:g.405_417dup, NG_045326.1:g.404_417dup, NG_045326.1:g.403_417dup, NG_045326.1:g.402_417dup, NG_045326.1:g.401_417dup, NG_045326.1:g.417_418insAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
    2.

    rs1491301278 has merged into rs869286061 [Homo sapiens]
      Variant type:
      DELINS
      Alleles:
      CC>-,C,CCC [Show Flanks]
      Chromosome:
      14:50668672 (GRCh38)
      14:51135390 (GRCh37)
      Canonical SPDI:
      NC_000014.9:50668667:CCCCCC:CCCC,NC_000014.9:50668667:CCCCCC:CCCCC,NC_000014.9:50668667:CCCCCC:CCCCCCC
      Gene:
      SAV1 (Varview)
      Functional Consequence:
      upstream_transcript_variant,2KB_upstream_variant
      Validated:
      by frequency,by alfa,by cluster
      MAF:
      CCCCC=0./0 (ALFA)
      HGVS:
      3.

      rs1491249768 [Homo sapiens]
        Variant type:
        DELINS
        Alleles:
        AT>- [Show Flanks]
        Chromosome:
        14:50656440 (GRCh38)
        14:51123158 (GRCh37)
        Canonical SPDI:
        NC_000014.9:50656438:TAT:T
        Gene:
        SAV1 (Varview)
        Functional Consequence:
        intron_variant
        Validated:
        by frequency,by cluster
        MAF:
        -=0.0213/79 (TWINSUK)
        HGVS:
        4.

        rs1491216014 [Homo sapiens]
          Variant type:
          SNV:
          Alleles:
          ->TTTTTTTTTTTTTTTTTTTTTTTCTTTTTTTTTTTTTTTTTTTTTTTT
          Chromosome:
          no mapping
          Canonical SPDI:
          5.

          rs1491163842 [Homo sapiens]
            Variant type:
            DEL
            Alleles:
            CT>- [Show Flanks]
            Chromosome:
            14:50665195 (GRCh38)
            14:51131913 (GRCh37)
            Canonical SPDI:
            NC_000014.9:50665194:CT:
            Gene:
            SAV1 (Varview)
            Functional Consequence:
            coding_sequence_variant,frameshift_variant
            Validated:
            by frequency,by cluster
            MAF:
            -=0.00001/1 (ExAC)
            HGVS:
            6.

            rs1491018258 [Homo sapiens]
              Variant type:
              DEL
              Alleles:
              AG>- [Show Flanks]
              Chromosome:
              14:50637663 (GRCh38)
              14:51104381 (GRCh37)
              Canonical SPDI:
              NC_000014.9:50637662:AG:
              Gene:
              SAV1 (Varview)
              Functional Consequence:
              intron_variant,genic_downstream_transcript_variant
              Validated:
              by frequency,by alfa,by cluster
              MAF:
              -=0./0 (ALFA)
              -=0.00009/9 (GnomAD)
              -=0.00053/9 (TOMMO)
              HGVS:
              7.

              rs1490942779 [Homo sapiens]
                Variant type:
                SNV
                Alleles:
                A>G [Show Flanks]
                Chromosome:
                14:50664180 (GRCh38)
                14:51130898 (GRCh37)
                Canonical SPDI:
                NC_000014.9:50664179:A:G
                Gene:
                SAV1 (Varview)
                Functional Consequence:
                intron_variant
                Validated:
                by frequency,by alfa,by cluster
                MAF:
                G=0.000094/1 (ALFA)
                G=0.000004/1 (TOPMED)
                G=0.000007/1 (GnomAD)
                HGVS:
                8.

                rs1490651201 [Homo sapiens]
                  Variant type:
                  SNV
                  Alleles:
                  A>G [Show Flanks]
                  Chromosome:
                  14:50648002 (GRCh38)
                  14:51114720 (GRCh37)
                  Canonical SPDI:
                  NC_000014.9:50648001:A:G
                  Gene:
                  SAV1 (Varview)
                  Functional Consequence:
                  intron_variant
                  Validated:
                  by frequency,by alfa,by cluster
                  MAF:
                  G=0.000071/1 (ALFA)
                  G=0.000004/1 (TOPMED)
                  G=0.000007/1 (GnomAD)
                  HGVS:
                  9.

                  rs1490541603 [Homo sapiens]
                    Variant type:
                    SNV
                    Alleles:
                    T>C [Show Flanks]
                    Chromosome:
                    14:50659279 (GRCh38)
                    14:51125997 (GRCh37)
                    Canonical SPDI:
                    NC_000014.9:50659278:T:C
                    Gene:
                    SAV1 (Varview)
                    Functional Consequence:
                    intron_variant
                    Validated:
                    by frequency,by alfa,by cluster
                    MAF:
                    C=0./0 (ALFA)
                    C=0.000004/1 (TOPMED)
                    C=0.000007/1 (GnomAD)
                    HGVS:
                    10.

                    rs1490500211 [Homo sapiens]
                      Variant type:
                      SNV
                      Alleles:
                      G>A [Show Flanks]
                      Chromosome:
                      14:50639519 (GRCh38)
                      14:51106237 (GRCh37)
                      Canonical SPDI:
                      NC_000014.9:50639518:G:A
                      Gene:
                      SAV1 (Varview)
                      Functional Consequence:
                      intron_variant,genic_downstream_transcript_variant
                      Validated:
                      by frequency,by alfa
                      MAF:
                      A=0./0 (ALFA)
                      A=0.000004/1 (TOPMED)
                      HGVS:
                      11.

                      rs1490443062 [Homo sapiens]
                        Variant type:
                        SNV
                        Alleles:
                        C>A,T [Show Flanks]
                        Chromosome:
                        14:50663276 (GRCh38)
                        14:51129994 (GRCh37)
                        Canonical SPDI:
                        NC_000014.9:50663275:C:A,NC_000014.9:50663275:C:T
                        Gene:
                        SAV1 (Varview)
                        Functional Consequence:
                        intron_variant
                        Validated:
                        by frequency,by alfa,by cluster
                        MAF:
                        T=0./0 (ALFA)
                        T=0.000007/1 (GnomAD)
                        HGVS:
                        12.

                        rs1490421385 [Homo sapiens]
                          Variant type:
                          SNV
                          Alleles:
                          C>G [Show Flanks]
                          Chromosome:
                          14:50661401 (GRCh38)
                          14:51128119 (GRCh37)
                          Canonical SPDI:
                          NC_000014.9:50661400:C:G
                          Gene:
                          SAV1 (Varview)
                          Functional Consequence:
                          intron_variant
                          Validated:
                          by frequency
                          MAF:
                          G=0.000007/1 (GnomAD)
                          HGVS:
                          13.

                          rs1490274083 [Homo sapiens]
                            Variant type:
                            SNV
                            Alleles:
                            T>C [Show Flanks]
                            Chromosome:
                            14:50666289 (GRCh38)
                            14:51133007 (GRCh37)
                            Canonical SPDI:
                            NC_000014.9:50666288:T:C
                            Gene:
                            SAV1 (Varview)
                            Functional Consequence:
                            intron_variant
                            Validated:
                            by frequency,by alfa,by cluster
                            MAF:
                            C=0./0 (ALFA)
                            C=0.000004/1 (TOPMED)
                            C=0.000007/1 (GnomAD)
                            HGVS:
                            14.

                            rs1490137754 [Homo sapiens]
                              Variant type:
                              SNV
                              Alleles:
                              T>A [Show Flanks]
                              Chromosome:
                              14:50634810 (GRCh38)
                              14:51101528 (GRCh37)
                              Canonical SPDI:
                              NC_000014.9:50634809:T:A
                              Gene:
                              SAV1 (Varview)
                              Functional Consequence:
                              genic_downstream_transcript_variant,3_prime_UTR_variant
                              Validated:
                              by frequency,by alfa,by cluster
                              MAF:
                              A=0.000071/1 (ALFA)
                              A=0.000093/13 (GnomAD)
                              A=0.000128/34 (TOPMED)
                              HGVS:
                              15.

                              rs1490092206 [Homo sapiens]
                                Variant type:
                                SNV
                                Alleles:
                                T>C [Show Flanks]
                                Chromosome:
                                14:50663219 (GRCh38)
                                14:51129937 (GRCh37)
                                Canonical SPDI:
                                NC_000014.9:50663218:T:C
                                Gene:
                                SAV1 (Varview)
                                Functional Consequence:
                                intron_variant
                                Validated:
                                by frequency,by alfa
                                MAF:
                                C=0./0 (ALFA)
                                C=0.000007/1 (GnomAD)
                                HGVS:
                                16.

                                rs1490059138 [Homo sapiens]
                                  Variant type:
                                  SNV
                                  Alleles:
                                  C>A [Show Flanks]
                                  Chromosome:
                                  14:50667078 (GRCh38)
                                  14:51133796 (GRCh37)
                                  Canonical SPDI:
                                  NC_000014.9:50667077:C:A
                                  Gene:
                                  SAV1 (Varview)
                                  Functional Consequence:
                                  intron_variant
                                  Validated:
                                  by frequency,by alfa,by cluster
                                  MAF:
                                  A=0./0 (ALFA)
                                  A=0.000008/2 (TOPMED)
                                  A=0.000014/2 (GnomAD)
                                  HGVS:
                                  17.

                                  rs1489835481 [Homo sapiens]
                                    Variant type:
                                    SNV
                                    Alleles:
                                    C>T [Show Flanks]
                                    Chromosome:
                                    14:50648694 (GRCh38)
                                    14:51115412 (GRCh37)
                                    Canonical SPDI:
                                    NC_000014.9:50648693:C:T
                                    Gene:
                                    SAV1 (Varview)
                                    Functional Consequence:
                                    intron_variant
                                    Validated:
                                    by frequency,by alfa
                                    MAF:
                                    T=0./0 (ALFA)
                                    T=0.000036/5 (GnomAD)
                                    HGVS:
                                    18.

                                    rs1489755028 [Homo sapiens]
                                      Variant type:
                                      SNV
                                      Alleles:
                                      G>C [Show Flanks]
                                      Chromosome:
                                      14:50658022 (GRCh38)
                                      14:51124740 (GRCh37)
                                      Canonical SPDI:
                                      NC_000014.9:50658021:G:C
                                      Gene:
                                      SAV1 (Varview)
                                      Functional Consequence:
                                      intron_variant
                                      Validated:
                                      by frequency,by alfa
                                      MAF:
                                      C=0./0 (ALFA)
                                      C=0.000004/1 (TOPMED)
                                      HGVS:
                                      19.

                                      rs1489598917 [Homo sapiens]
                                        Variant type:
                                        DELINS
                                        Alleles:
                                        CT>- [Show Flanks]
                                        Chromosome:
                                        14:50639348 (GRCh38)
                                        14:51106066 (GRCh37)
                                        Canonical SPDI:
                                        NC_000014.9:50639344:TCTCT:TCT
                                        Gene:
                                        SAV1 (Varview)
                                        Functional Consequence:
                                        intron_variant,genic_downstream_transcript_variant
                                        Validated:
                                        by frequency,by alfa,by cluster
                                        MAF:
                                        TCT=0./0 (ALFA)
                                        -=0.00003/8 (TOPMED)
                                        -=0.000033/4 (GnomAD)
                                        HGVS:
                                        20.

                                        rs1489420188 [Homo sapiens]
                                          Variant type:
                                          SNV
                                          Alleles:
                                          C>T [Show Flanks]
                                          Chromosome:
                                          14:50648742 (GRCh38)
                                          14:51115460 (GRCh37)
                                          Canonical SPDI:
                                          NC_000014.9:50648741:C:T
                                          Gene:
                                          SAV1 (Varview)
                                          Functional Consequence:
                                          intron_variant
                                          Validated:
                                          by frequency,by alfa
                                          MAF:
                                          T=0./0 (ALFA)
                                          T=0.000004/1 (TOPMED)
                                          HGVS:

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