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1.

rs1491512623 [Homo sapiens]
    Variant type:
    DEL
    Alleles:
    CA>- [Show Flanks]
    Chromosome:
    4:83459144 (GRCh38)
    4:84380297 (GRCh37)
    Canonical SPDI:
    NC_000004.12:83459143:CA:
    Gene:
    MRPS18C (Varview), ABRAXAS1 (Varview)
    Functional Consequence:
    intron_variant,500B_downstream_variant,downstream_transcript_variant
    Validated:
    by frequency,by alfa
    MAF:
    -=0./0 (ALFA)
    HGVS:
    2.

    rs1491120145 has merged into rs59202184 [Homo sapiens]
      Variant type:
      DELINS
      Alleles:
      AAAAAAAAAAAAAAA>-,A,AA,AAA,AAAA,AAAAA,AAAAAA,AAAAAAA,AAAAAAAA,AAAAAAAAA,AAAAAAAAAA,AAAAAAAAAAA,AAAAAAAAAAAA,AAAAAAAAAAAAA,AAAAAAAAAAAAAA,AAAAAAAAAAAAAAAA,AAAAAAAAAAAAAAAAA,AAAAAAAAAAAAAAAAAA,AAAAAAAAAAAAAAAAAAA,AAAAAAAAAAAAAAAAAAAA,AAAAAAAAAAAAAAAAAAAAA,AAAAAAAAAAAAAAAAAAAAAA,AAAAAAAAAAAAAAAAAAAAAAAAAAA,AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA,AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA,AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA,AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA,AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA,AAAAAAAAAAAAAAAAAATTCCATAAAAAAAAAAAAAAAAAAAAAAAAA [Show Flanks]
      Chromosome:
      4:83459154 (GRCh38)
      4:84380307 (GRCh37)
      Canonical SPDI:
      NC_000004.12:83459144:AAAAAAAAAAAAAAAAAAAAAAAA:AAAAAAAAA,NC_000004.12:83459144:AAAAAAAAAAAAAAAAAAAAAAAA:AAAAAAAAAA,NC_000004.12:83459144:AAAAAAAAAAAAAAAAAAAAAAAA:AAAAAAAAAAA,NC_000004.12:83459144:AAAAAAAAAAAAAAAAAAAAAAAA:AAAAAAAAAAAA,NC_000004.12:83459144:AAAAAAAAAAAAAAAAAAAAAAAA:AAAAAAAAAAAAA,NC_000004.12:83459144:AAAAAAAAAAAAAAAAAAAAAAAA:AAAAAAAAAAAAAA,NC_000004.12:83459144:AAAAAAAAAAAAAAAAAAAAAAAA:AAAAAAAAAAAAAAA,NC_000004.12:83459144:AAAAAAAAAAAAAAAAAAAAAAAA:AAAAAAAAAAAAAAAA,NC_000004.12:83459144:AAAAAAAAAAAAAAAAAAAAAAAA:AAAAAAAAAAAAAAAAA,NC_000004.12:83459144:AAAAAAAAAAAAAAAAAAAAAAAA:AAAAAAAAAAAAAAAAAA,NC_000004.12:83459144:AAAAAAAAAAAAAAAAAAAAAAAA:AAAAAAAAAAAAAAAAAAA,NC_000004.12:83459144:AAAAAAAAAAAAAAAAAAAAAAAA:AAAAAAAAAAAAAAAAAAAA,NC_000004.12:83459144:AAAAAAAAAAAAAAAAAAAAAAAA:AAAAAAAAAAAAAAAAAAAAA,NC_000004.12:83459144:AAAAAAAAAAAAAAAAAAAAAAAA:AAAAAAAAAAAAAAAAAAAAAA,NC_000004.12:83459144:AAAAAAAAAAAAAAAAAAAAAAAA:AAAAAAAAAAAAAAAAAAAAAAA,NC_000004.12:83459144:AAAAAAAAAAAAAAAAAAAAAAAA:AAAAAAAAAAAAAAAAAAAAAAAAA,NC_000004.12:83459144:AAAAAAAAAAAAAAAAAAAAAAAA:AAAAAAAAAAAAAAAAAAAAAAAAAA,NC_000004.12:83459144:AAAAAAAAAAAAAAAAAAAAAAAA:AAAAAAAAAAAAAAAAAAAAAAAAAAA,NC_000004.12:83459144:AAAAAAAAAAAAAAAAAAAAAAAA:AAAAAAAAAAAAAAAAAAAAAAAAAAAA,NC_000004.12:83459144:AAAAAAAAAAAAAAAAAAAAAAAA:AAAAAAAAAAAAAAAAAAAAAAAAAAAAA,NC_000004.12:83459144:AAAAAAAAAAAAAAAAAAAAAAAA:AAAAAAAAAAAAAAAAAAAAAAAAAAAAAA,NC_000004.12:83459144:AAAAAAAAAAAAAAAAAAAAAAAA:AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA,NC_000004.12:83459144:AAAAAAAAAAAAAAAAAAAAAAAA:AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA,NC_000004.12:83459144:AAAAAAAAAAAAAAAAAAAAAAAA:AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA,NC_000004.12:83459144:AAAAAAAAAAAAAAAAAAAAAAAA:AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA,NC_000004.12:83459144:AAAAAAAAAAAAAAAAAAAAAAAA:AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA,NC_000004.12:83459144:AAAAAAAAAAAAAAAAAAAAAAAA:AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA,NC_000004.12:83459144:AAAAAAAAAAAAAAAAAAAAAAAA:AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA,NC_000004.12:83459144:AAAAAAAAAAAAAAAAAAAAAAAA:AAAAAAAAAAAAAAAAAAAAAAAAAAATTCCATAAAAAAAAAAAAAAAAAAAAAAAAA
      Gene:
      MRPS18C (Varview), ABRAXAS1 (Varview)
      Functional Consequence:
      500B_downstream_variant,intron_variant,downstream_transcript_variant
      Validated:
      by frequency,by alfa,by cluster
      MAF:
      AAAAAAAAA=0./0 (ALFA)
      AAAAAAAAA=0./0 (GENOME_DK)
      HGVS:
      NC_000004.12:g.83459154_83459168del, NC_000004.12:g.83459155_83459168del, NC_000004.12:g.83459156_83459168del, NC_000004.12:g.83459157_83459168del, NC_000004.12:g.83459158_83459168del, NC_000004.12:g.83459159_83459168del, NC_000004.12:g.83459160_83459168del, NC_000004.12:g.83459161_83459168del, NC_000004.12:g.83459162_83459168del, NC_000004.12:g.83459163_83459168del, NC_000004.12:g.83459164_83459168del, NC_000004.12:g.83459165_83459168del, NC_000004.12:g.83459166_83459168del, NC_000004.12:g.83459167_83459168del, NC_000004.12:g.83459168del, NC_000004.12:g.83459168dup, NC_000004.12:g.83459167_83459168dup, NC_000004.12:g.83459166_83459168dup, NC_000004.12:g.83459165_83459168dup, NC_000004.12:g.83459164_83459168dup, NC_000004.12:g.83459163_83459168dup, NC_000004.12:g.83459162_83459168dup, NC_000004.12:g.83459157_83459168dup, NC_000004.12:g.83459152_83459168dup, NC_000004.12:g.83459151_83459168dup, NC_000004.12:g.83459145_83459168dup, NC_000004.12:g.83459168_83459169insAAAAAAAAAAAAAAAAAAAAAAAAAA, NC_000004.12:g.83459168_83459169insAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA, NC_000004.12:g.83459145_83459168A[27]TTCCATAAAAAAAAAAAAAAAAAAAAAAAAA[1], NC_000004.11:g.84380307_84380321del, NC_000004.11:g.84380308_84380321del, NC_000004.11:g.84380309_84380321del, NC_000004.11:g.84380310_84380321del, NC_000004.11:g.84380311_84380321del, NC_000004.11:g.84380312_84380321del, NC_000004.11:g.84380313_84380321del, NC_000004.11:g.84380314_84380321del, NC_000004.11:g.84380315_84380321del, NC_000004.11:g.84380316_84380321del, NC_000004.11:g.84380317_84380321del, NC_000004.11:g.84380318_84380321del, NC_000004.11:g.84380319_84380321del, NC_000004.11:g.84380320_84380321del, NC_000004.11:g.84380321del, NC_000004.11:g.84380321dup, NC_000004.11:g.84380320_84380321dup, NC_000004.11:g.84380319_84380321dup, NC_000004.11:g.84380318_84380321dup, NC_000004.11:g.84380317_84380321dup, NC_000004.11:g.84380316_84380321dup, NC_000004.11:g.84380315_84380321dup, NC_000004.11:g.84380310_84380321dup, NC_000004.11:g.84380305_84380321dup, NC_000004.11:g.84380304_84380321dup, NC_000004.11:g.84380298_84380321dup, NC_000004.11:g.84380321_84380322insAAAAAAAAAAAAAAAAAAAAAAAAAA, NC_000004.11:g.84380321_84380322insAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA, NC_000004.11:g.84380298_84380321A[27]TTCCATAAAAAAAAAAAAAAAAAAAAAAAAA[1], NG_051599.1:g.31020_31034del, NG_051599.1:g.31021_31034del, NG_051599.1:g.31022_31034del, NG_051599.1:g.31023_31034del, NG_051599.1:g.31024_31034del, NG_051599.1:g.31025_31034del, NG_051599.1:g.31026_31034del, NG_051599.1:g.31027_31034del, NG_051599.1:g.31028_31034del, NG_051599.1:g.31029_31034del, NG_051599.1:g.31030_31034del, NG_051599.1:g.31031_31034del, NG_051599.1:g.31032_31034del, NG_051599.1:g.31033_31034del, NG_051599.1:g.31034del, NG_051599.1:g.31034dup, NG_051599.1:g.31033_31034dup, NG_051599.1:g.31032_31034dup, NG_051599.1:g.31031_31034dup, NG_051599.1:g.31030_31034dup, NG_051599.1:g.31029_31034dup, NG_051599.1:g.31028_31034dup, NG_051599.1:g.31023_31034dup, NG_051599.1:g.31018_31034dup, NG_051599.1:g.31017_31034dup, NG_051599.1:g.31011_31034dup, NG_051599.1:g.31034_31035insTTTTTTTTTTTTTTTTTTTTTTTTTT, NG_051599.1:g.31034_31035insTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT, NG_051599.1:g.31011_31034T[25]ATGGAATTTTTTTTTTTTTTTTTTTTTTTTTTT[1]
      3.

      rs1490954928 [Homo sapiens]
        Variant type:
        SNV
        Alleles:
        A>G [Show Flanks]
        Chromosome:
        4:83456522 (GRCh38)
        4:84377675 (GRCh37)
        Canonical SPDI:
        NC_000004.12:83456521:A:G
        Gene:
        MRPS18C (Varview), HELQ (Varview)
        Functional Consequence:
        intron_variant,upstream_transcript_variant,2KB_upstream_variant
        Validated:
        by frequency,by alfa
        MAF:
        G=0./0 (ALFA)
        G=0.000007/1 (GnomAD)
        HGVS:
        4.

        rs1490748844 [Homo sapiens]
          Variant type:
          SNV
          Alleles:
          C>T [Show Flanks]
          Chromosome:
          4:83456862 (GRCh38)
          4:84378015 (GRCh37)
          Canonical SPDI:
          NC_000004.12:83456861:C:T
          Gene:
          MRPS18C (Varview), HELQ (Varview)
          Functional Consequence:
          intron_variant,upstream_transcript_variant,2KB_upstream_variant
          Validated:
          by frequency,by alfa,by cluster
          MAF:
          T=0.000224/1 (ALFA)
          T=0.000007/1 (GnomAD)
          T=0.000223/1 (Estonian)
          HGVS:
          5.

          rs1490740862 [Homo sapiens]
            Variant type:
            SNV
            Alleles:
            T>A [Show Flanks]
            Chromosome:
            4:83458976 (GRCh38)
            4:84380129 (GRCh37)
            Canonical SPDI:
            NC_000004.12:83458975:T:A
            Gene:
            MRPS18C (Varview)
            Functional Consequence:
            intron_variant
            Validated:
            by frequency,by alfa,by cluster
            MAF:
            A=0./0 (ALFA)
            A=0.000004/1 (TOPMED)
            A=0.000007/1 (GnomAD)
            HGVS:
            6.

            rs1490673724 [Homo sapiens]
              Variant type:
              SNV
              Alleles:
              C>A,T [Show Flanks]
              Chromosome:
              4:83456690 (GRCh38)
              4:84377843 (GRCh37)
              Canonical SPDI:
              NC_000004.12:83456689:C:A,NC_000004.12:83456689:C:T
              Gene:
              MRPS18C (Varview), HELQ (Varview)
              Functional Consequence:
              intron_variant,upstream_transcript_variant,2KB_upstream_variant
              Validated:
              by frequency,by alfa
              MAF:
              T=0./0 (ALFA)
              HGVS:
              7.

              rs1490617272 [Homo sapiens]
                Variant type:
                SNV
                Alleles:
                G>A,C [Show Flanks]
                Chromosome:
                4:83455917 (GRCh38)
                4:84377070 (GRCh37)
                Canonical SPDI:
                NC_000004.12:83455916:G:A,NC_000004.12:83455916:G:C
                Gene:
                MRPS18C (Varview), HELQ (Varview)
                Functional Consequence:
                upstream_transcript_variant,2KB_upstream_variant
                Validated:
                by frequency,by alfa,by cluster
                MAF:
                A=0./0 (ALFA)
                A=0.000004/1 (TOPMED)
                C=0.000071/1 (TOMMO)
                HGVS:
                8.

                rs1490440991 [Homo sapiens]
                  Variant type:
                  DELINS
                  Alleles:
                  AAAG>- [Show Flanks]
                  Chromosome:
                  4:83457603 (GRCh38)
                  4:84378756 (GRCh37)
                  Canonical SPDI:
                  NC_000004.12:83457599:AAGAAAG:AAG
                  Gene:
                  MRPS18C (Varview), HELQ (Varview)
                  Functional Consequence:
                  intron_variant,upstream_transcript_variant,2KB_upstream_variant
                  Validated:
                  by frequency,by alfa,by cluster
                  MAF:
                  AAG=0./0 (ALFA)
                  -=0.000014/2 (GnomAD)
                  -=0.000026/7 (TOPMED)
                  HGVS:
                  9.

                  rs1490266368 [Homo sapiens]
                    Variant type:
                    SNV
                    Alleles:
                    T>C [Show Flanks]
                    Chromosome:
                    4:83460193 (GRCh38)
                    4:84381346 (GRCh37)
                    Canonical SPDI:
                    NC_000004.12:83460192:T:C
                    Gene:
                    MRPS18C (Varview), ABRAXAS1 (Varview)
                    Functional Consequence:
                    intron_variant,3_prime_UTR_variant,genic_downstream_transcript_variant
                    Validated:
                    by frequency,by alfa,by cluster
                    MAF:
                    C=0./0 (ALFA)
                    C=0.000004/1 (TOPMED)
                    C=0.000007/1 (GnomAD)
                    HGVS:
                    10.

                    rs1489857512 [Homo sapiens]
                      Variant type:
                      DELINS
                      Alleles:
                      GTTT>- [Show Flanks]
                      Chromosome:
                      4:83457259 (GRCh38)
                      4:84378412 (GRCh37)
                      Canonical SPDI:
                      NC_000004.12:83457256:TTGTTT:TT
                      Gene:
                      MRPS18C (Varview), HELQ (Varview)
                      Functional Consequence:
                      intron_variant,upstream_transcript_variant,2KB_upstream_variant
                      Validated:
                      by frequency,by alfa,by cluster
                      MAF:
                      TT=0./0 (ALFA)
                      -=0.00035/6 (TOMMO)
                      HGVS:
                      11.

                      rs1489457769 [Homo sapiens]
                        Variant type:
                        DELINS
                        Alleles:
                        AG>- [Show Flanks]
                        Chromosome:
                        4:83456244 (GRCh38)
                        4:84377397 (GRCh37)
                        Canonical SPDI:
                        NC_000004.12:83456241:AGAG:AG
                        Gene:
                        MRPS18C (Varview), HELQ (Varview)
                        Functional Consequence:
                        intron_variant,upstream_transcript_variant,2KB_upstream_variant
                        Validated:
                        by frequency,by alfa
                        MAF:
                        AGAG=0./0 (ALFA)
                        -=0.000004/1 (TOPMED)
                        HGVS:
                        12.

                        rs1489157750 [Homo sapiens]
                          Variant type:
                          SNV
                          Alleles:
                          T>A [Show Flanks]
                          Chromosome:
                          4:83457309 (GRCh38)
                          4:84378462 (GRCh37)
                          Canonical SPDI:
                          NC_000004.12:83457308:T:A
                          Gene:
                          MRPS18C (Varview), HELQ (Varview)
                          Functional Consequence:
                          intron_variant,upstream_transcript_variant,2KB_upstream_variant
                          Validated:
                          by frequency,by alfa,by cluster
                          MAF:
                          A=0./0 (ALFA)
                          A=0.000004/1 (TOPMED)
                          A=0.000007/1 (GnomAD)
                          T=0.5/1 (SGDP_PRJ)
                          HGVS:
                          13.

                          rs1488844139 [Homo sapiens]
                            Variant type:
                            SNV
                            Alleles:
                            A>C [Show Flanks]
                            Chromosome:
                            4:83454688 (GRCh38)
                            4:84375841 (GRCh37)
                            Canonical SPDI:
                            NC_000004.12:83454687:A:C
                            Gene:
                            MRPS18C (Varview), HELQ (Varview)
                            Functional Consequence:
                            intron_variant,upstream_transcript_variant,2KB_upstream_variant
                            Validated:
                            by frequency,by alfa,by cluster
                            MAF:
                            C=0.000142/2 (ALFA)
                            C=0./0 (GnomAD)
                            C=0.000004/1 (TOPMED)
                            HGVS:
                            14.

                            rs1488627822 [Homo sapiens]
                              Variant type:
                              SNV
                              Alleles:
                              C>G [Show Flanks]
                              Chromosome:
                              4:83461258 (GRCh38)
                              4:84382411 (GRCh37)
                              Canonical SPDI:
                              NC_000004.12:83461257:C:G
                              Gene:
                              MRPS18C (Varview), ABRAXAS1 (Varview)
                              Functional Consequence:
                              genic_downstream_transcript_variant,3_prime_UTR_variant
                              Validated:
                              by frequency,by alfa
                              MAF:
                              G=0./0 (ALFA)
                              G=0.000011/3 (TOPMED)
                              HGVS:
                              15.

                              rs1487455174 [Homo sapiens]
                                Variant type:
                                SNV
                                Alleles:
                                C>T [Show Flanks]
                                Chromosome:
                                4:83454681 (GRCh38)
                                4:84375834 (GRCh37)
                                Canonical SPDI:
                                NC_000004.12:83454680:C:T
                                Gene:
                                MRPS18C (Varview), HELQ (Varview)
                                Functional Consequence:
                                intron_variant,upstream_transcript_variant,2KB_upstream_variant
                                Validated:
                                by frequency,by alfa
                                MAF:
                                T=0./0 (ALFA)
                                T=0.000004/1 (TOPMED)
                                HGVS:
                                17.

                                rs1486566710 [Homo sapiens]
                                  Variant type:
                                  SNV
                                  Alleles:
                                  T>C [Show Flanks]
                                  Chromosome:
                                  4:83456190 (GRCh38)
                                  4:84377343 (GRCh37)
                                  Canonical SPDI:
                                  NC_000004.12:83456189:T:C
                                  Gene:
                                  MRPS18C (Varview), HELQ (Varview)
                                  Functional Consequence:
                                  intron_variant,upstream_transcript_variant,2KB_upstream_variant
                                  Validated:
                                  by frequency,by alfa,by cluster
                                  MAF:
                                  C=0./0 (ALFA)
                                  C=0.000004/1 (GnomAD_exomes)
                                  C=0.000007/1 (GnomAD)
                                  C=0.000008/2 (TOPMED)
                                  HGVS:
                                  18.

                                  rs1485888053 [Homo sapiens]
                                    Variant type:
                                    SNV
                                    Alleles:
                                    C>G [Show Flanks]
                                    Chromosome:
                                    4:83456342 (GRCh38)
                                    4:84377495 (GRCh37)
                                    Canonical SPDI:
                                    NC_000004.12:83456341:C:G
                                    Gene:
                                    MRPS18C (Varview), HELQ (Varview)
                                    Functional Consequence:
                                    intron_variant,upstream_transcript_variant,2KB_upstream_variant
                                    Validated:
                                    by frequency,by alfa,by cluster
                                    MAF:
                                    G=0./0 (ALFA)
                                    G=0.000004/1 (TOPMED)
                                    G=0.000007/1 (GnomAD)
                                    HGVS:
                                    19.

                                    rs1485688778 [Homo sapiens]
                                      Variant type:
                                      SNV
                                      Alleles:
                                      A>G [Show Flanks]
                                      Chromosome:
                                      4:83459866 (GRCh38)
                                      4:84381019 (GRCh37)
                                      Canonical SPDI:
                                      NC_000004.12:83459865:A:G
                                      Gene:
                                      MRPS18C (Varview), ABRAXAS1 (Varview)
                                      Functional Consequence:
                                      intron_variant,genic_downstream_transcript_variant,3_prime_UTR_variant
                                      Validated:
                                      by frequency,by alfa
                                      MAF:
                                      G=0./0 (ALFA)
                                      G=0.000004/1 (TOPMED)
                                      HGVS:
                                      20.

                                      rs1485668325 [Homo sapiens]
                                        Variant type:
                                        SNV
                                        Alleles:
                                        T>C [Show Flanks]
                                        Chromosome:
                                        4:83459298 (GRCh38)
                                        4:84380451 (GRCh37)
                                        Canonical SPDI:
                                        NC_000004.12:83459297:T:C
                                        Gene:
                                        MRPS18C (Varview), ABRAXAS1 (Varview)
                                        Functional Consequence:
                                        intron_variant,downstream_transcript_variant,500B_downstream_variant
                                        Validated:
                                        by frequency,by alfa,by cluster
                                        MAF:
                                        C=0./0 (ALFA)
                                        C=0.000004/1 (TOPMED)
                                        C=0.000007/1 (GnomAD)
                                        C=0.001203/20 (TOMMO)
                                        HGVS:

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