Name: rs1491495244
Published: September 21, 2022
License: Open Access

Welcome to the Reference SNP (rs) Report

All alleles are reported in the Forward orientation. Click on the Variant Details tab for details on Genomic Placement, Gene, and Amino Acid changes. HGVS names are in the HGVS tab.

Reference SNP (rs) Report

This page reports data for a single dbSNP Reference SNP variation (RefSNP or rs) from the new redesigned dbSNP build.
Top of the page reports a concise summary for the rs, with more specific details included in the corresponding tabs below.
All alleles are reported in the Forward orientation. Use the Genomic View to inspect the nucleotides flanking the variant, and its neighbors.
For more information see Help documentation.

rs1491495244

Current Build 156

Released September 21, 2022

Organism: Homo sapiens
Position: chr1:154426109 (GRCh38.p14) Help
The anchor position for this RefSNP. Includes all nucleotides potentially affected by this change, thus it can differ from HGVS, which is right-shifted. See here for details.
Alleles: ins(CA)₇TA / ins(CA)₆TA / ins(CA)₅…
ins(CA)₇TA / ins(CA)₆TA / ins(CA)₅TA / ins(CA)₃TA / insCACATA / insCATA
Variation Type: Indel Insertion and Deletion
Frequency: ins(CA)₇TA=0.00000 (0/11862, ALFA)
ins(CA)₆TA=0.00000 (0/11862, ALFA)
ins(CA)₅TA=0.00000 (0/11862, ALFA) (+ 3 more)
ins(CA)₃TA=0.00000 (0/11862, ALFA)
insCACATA=0.00000 (0/11862, ALFA)
insCATA=0.00000 (0/11862, ALFA)

Clinical Significance: Not Reported in ClinVar
Gene : Consequence: IL6R : Intron Variant
Publications: 0 citations
Genomic View: See rs on genome

ALFA Allele Frequency
The ALFA project provide aggregate allele frequency from dbGaP. More information is available on the project page including descriptions, data access, and terms of use.

Release Version: 20231103111315

Population	Group	Sample Size	Ref Allele	Alt Allele	Ref HMOZ	HWEP
Total	Global	11862	A=1.00000	ACACACACACACACATA=0.00000, ACACACACACACATA=0.00000, ACACACACACATA=0.00000, ACACACATA=0.00000, ACACATA=0.00000, ACATA=0.00000	1.0	N/A
European	Sub	7618	A=1.0000	ACACACACACACACATA=0.0000, ACACACACACACATA=0.0000, ACACACACACATA=0.0000, ACACACATA=0.0000, ACACATA=0.0000, ACATA=0.0000	1.0	N/A
African	Sub	2816	A=1.0000	ACACACACACACACATA=0.0000, ACACACACACACATA=0.0000, ACACACACACATA=0.0000, ACACACATA=0.0000, ACACATA=0.0000, ACATA=0.0000	1.0	N/A
African Others	Sub	108	A=1.000	ACACACACACACACATA=0.000, ACACACACACACATA=0.000, ACACACACACATA=0.000, ACACACATA=0.000, ACACATA=0.000, ACATA=0.000	1.0	N/A
African American	Sub	2708	A=1.0000	ACACACACACACACATA=0.0000, ACACACACACACATA=0.0000, ACACACACACATA=0.0000, ACACACATA=0.0000, ACACATA=0.0000, ACATA=0.0000	1.0	N/A
Asian	Sub	108	A=1.000	ACACACACACACACATA=0.000, ACACACACACACATA=0.000, ACACACACACATA=0.000, ACACACATA=0.000, ACACATA=0.000, ACATA=0.000	1.0	N/A
East Asian	Sub	84	A=1.00	ACACACACACACACATA=0.00, ACACACACACACATA=0.00, ACACACACACATA=0.00, ACACACATA=0.00, ACACATA=0.00, ACATA=0.00	1.0	N/A
Other Asian	Sub	24	A=1.00	ACACACACACACACATA=0.00, ACACACACACACATA=0.00, ACACACACACATA=0.00, ACACACATA=0.00, ACACATA=0.00, ACATA=0.00	1.0	N/A
Latin American 1	Sub	146	A=1.000	ACACACACACACACATA=0.000, ACACACACACACATA=0.000, ACACACACACATA=0.000, ACACACATA=0.000, ACACATA=0.000, ACATA=0.000	1.0	N/A
Latin American 2	Sub	610	A=1.000	ACACACACACACACATA=0.000, ACACACACACACATA=0.000, ACACACACACATA=0.000, ACACACATA=0.000, ACACATA=0.000, ACATA=0.000	1.0	N/A
South Asian	Sub	94	A=1.00	ACACACACACACACATA=0.00, ACACACACACACATA=0.00, ACACACACACATA=0.00, ACACACATA=0.00, ACACATA=0.00, ACATA=0.00	1.0	N/A
Other	Sub	470	A=1.000	ACACACACACACACATA=0.000, ACACACACACACATA=0.000, ACACACACACATA=0.000, ACACACATA=0.000, ACACATA=0.000, ACATA=0.000	1.0	N/A

Frequency tab displays a table of the reference and alternate allele frequencies reported by various studies and populations. Table lines, where Population="Global" refer to the entire study population, whereas lines, where Group="Sub", refer to a study-specific population subgroupings (i.e. AFR, CAU, etc.), if available. Frequency for the alternate allele (Alt Allele) is a ratio of samples observed-to-total, where the numerator (observed samples) is the number of chromosomes in the study with the minor allele present (found in "Sample size", where Group="Sub"), and the denominator (total samples) is the total number of all chromosomes in the study for the variant (found in "Sample size", where Group="Study-wide" and Population="Global").

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Study	Population	Group	Sample Size	Ref Allele	Alt Allele
Allele Frequency Aggregator	Total	Global	11862	A=1.00000	ins(CA)₇TA=0.00000, ins(CA)₆TA=0.00000, ins(CA)₅TA=0.00000, ins(CA)₃TA=0.00000, insCACATA=0.00000, insCATA=0.00000
Allele Frequency Aggregator	European	Sub	7618	A=1.0000	ins(CA)₇TA=0.0000, ins(CA)₆TA=0.0000, ins(CA)₅TA=0.0000, ins(CA)₃TA=0.0000, insCACATA=0.0000, insCATA=0.0000
Allele Frequency Aggregator	African	Sub	2816	A=1.0000	ins(CA)₇TA=0.0000, ins(CA)₆TA=0.0000, ins(CA)₅TA=0.0000, ins(CA)₃TA=0.0000, insCACATA=0.0000, insCATA=0.0000
Allele Frequency Aggregator	Latin American 2	Sub	610	A=1.000	ins(CA)₇TA=0.000, ins(CA)₆TA=0.000, ins(CA)₅TA=0.000, ins(CA)₃TA=0.000, insCACATA=0.000, insCATA=0.000
Allele Frequency Aggregator	Other	Sub	470	A=1.000	ins(CA)₇TA=0.000, ins(CA)₆TA=0.000, ins(CA)₅TA=0.000, ins(CA)₃TA=0.000, insCACATA=0.000, insCATA=0.000
Allele Frequency Aggregator	Latin American 1	Sub	146	A=1.000	ins(CA)₇TA=0.000, ins(CA)₆TA=0.000, ins(CA)₅TA=0.000, ins(CA)₃TA=0.000, insCACATA=0.000, insCATA=0.000
Allele Frequency Aggregator	Asian	Sub	108	A=1.000	ins(CA)₇TA=0.000, ins(CA)₆TA=0.000, ins(CA)₅TA=0.000, ins(CA)₃TA=0.000, insCACATA=0.000, insCATA=0.000
Allele Frequency Aggregator	South Asian	Sub	94	A=1.00	ins(CA)₇TA=0.00, ins(CA)₆TA=0.00, ins(CA)₅TA=0.00, ins(CA)₃TA=0.00, insCACATA=0.00, insCATA=0.00

Variant Details tab shows known variant placements on genomic sequences: chromosomes (NC_), RefSeqGene, pseudogenes or genomic regions (NG_), and in a separate table: on transcripts (NM_) and protein sequences (NP_). The corresponding transcript and protein locations are listed in adjacent lines, along with molecular consequences from Sequence Ontology. When no protein placement is available, only the transcript is listed. Column "Codon[Amino acid]" shows the actual base change in the format of "Reference > Alternate" allele, including the nucleotide codon change in transcripts, and the amino acid change in proteins, respectively, allowing for known ribosomal slippage sites. To view nucleotides adjacent to the variant use the Genomic View at the bottom of the page - zoom into the sequence until the nucleotides around the variant become visible.

Genomic Placements

Sequence name	Change
GRCh38.p14 chr 1	NC_000001.11:g.154426109AC[7]ATA[1]
GRCh38.p14 chr 1	NC_000001.11:g.154426109AC[6]ATA[1]
GRCh38.p14 chr 1	NC_000001.11:g.154426109AC[5]ATA[1]
GRCh38.p14 chr 1	NC_000001.11:g.154426109AC[3]ATA[1]
GRCh38.p14 chr 1	NC_000001.11:g.154426109AC[2]ATA[1]
GRCh38.p14 chr 1	NC_000001.11:g.154426109_154426110insCATA
GRCh37.p13 chr 1	NC_000001.10:g.154398585AC[7]ATA[1]
GRCh37.p13 chr 1	NC_000001.10:g.154398585AC[6]ATA[1]
GRCh37.p13 chr 1	NC_000001.10:g.154398585AC[5]ATA[1]
GRCh37.p13 chr 1	NC_000001.10:g.154398585AC[3]ATA[1]
GRCh37.p13 chr 1	NC_000001.10:g.154398585AC[2]ATA[1]
GRCh37.p13 chr 1	NC_000001.10:g.154398585_154398586insCATA
IL6R RefSeqGene	NG_012087.1:g.25917AC[7]ATA[1]
IL6R RefSeqGene	NG_012087.1:g.25917AC[6]ATA[1]
IL6R RefSeqGene	NG_012087.1:g.25917AC[5]ATA[1]
IL6R RefSeqGene	NG_012087.1:g.25917AC[3]ATA[1]
IL6R RefSeqGene	NG_012087.1:g.25917AC[2]ATA[1]
IL6R RefSeqGene	NG_012087.1:g.25917_25918insCATA

Gene: IL6R, interleukin 6 receptor (plus strand)

Molecule type	Change	Amino acid[Codon]	SO Term
IL6R transcript variant 1	NM_000565.4:c.86-3087_86-… NM_000565.4:c.86-3087_86-3086insCACACACACACACATA	N/A	Intron Variant
IL6R transcript variant 3	NM_001206866.2:c.86-3087_… NM_001206866.2:c.86-3087_86-3086insCACACACACACACATA	N/A	Intron Variant
IL6R transcript variant 4	NM_001382769.1:c.86-3087_… NM_001382769.1:c.86-3087_86-3086insCACACACACACACATA	N/A	Intron Variant
IL6R transcript variant 5	NM_001382770.1:c.86-3087_… NM_001382770.1:c.86-3087_86-3086insCACACACACACACATA	N/A	Intron Variant
IL6R transcript variant 6	NM_001382771.1:c.86-3087_… NM_001382771.1:c.86-3087_86-3086insCACACACACACACATA	N/A	Intron Variant
IL6R transcript variant 7	NM_001382772.1:c.86-3087_… NM_001382772.1:c.86-3087_86-3086insCACACACACACACATA	N/A	Intron Variant
IL6R transcript variant 8	NM_001382773.1:c.86-3087_… NM_001382773.1:c.86-3087_86-3086insCACACACACACACATA	N/A	Intron Variant
IL6R transcript variant 9	NM_001382774.1:c.86-3087_… NM_001382774.1:c.86-3087_86-3086insCACACACACACACATA	N/A	Intron Variant
IL6R transcript variant 2	NM_181359.3:c.86-3087_86-… NM_181359.3:c.86-3087_86-3086insCACACACACACACATA	N/A	Intron Variant
IL6R transcript variant X8	XM_005245139.2:c.86-3087_… XM_005245139.2:c.86-3087_86-3086insCACACACACACACATA	N/A	Intron Variant
IL6R transcript variant X1	XM_017001199.2:c.86-3087_… XM_017001199.2:c.86-3087_86-3086insCACACACACACACATA	N/A	Intron Variant
IL6R transcript variant X2	XM_047419648.1:c.23-3087_… XM_047419648.1:c.23-3087_23-3086insCACACACACACACATA	N/A	Intron Variant
IL6R transcript variant X3	XM_047419649.1:c.23-3087_… XM_047419649.1:c.23-3087_23-3086insCACACACACACACATA	N/A	Intron Variant
IL6R transcript variant X4	XM_047419650.1:c.23-3087_… XM_047419650.1:c.23-3087_23-3086insCACACACACACACATA	N/A	Intron Variant
IL6R transcript variant X5	XM_047419654.1:c.86-3087_… XM_047419654.1:c.86-3087_86-3086insCACACACACACACATA	N/A	Intron Variant
IL6R transcript variant X6	XM_047419655.1:c.86-3087_… XM_047419655.1:c.86-3087_86-3086insCACACACACACACATA	N/A	Intron Variant
IL6R transcript variant X7	XM_047419656.1:c.86-3087_… XM_047419656.1:c.86-3087_86-3086insCACACACACACACATA	N/A	Intron Variant
IL6R transcript variant X9	XM_047419657.1:c.86-3087_… XM_047419657.1:c.86-3087_86-3086insCACACACACACACATA	N/A	Intron Variant

Clinical Significance tab shows a list of clinical significance entries from ClinVar associated with the variation, per allele. Click on the RCV accession (i.e. RCV000001615.2) or Allele ID (i.e. 12274) to access full ClinVar report.

Not Reported in ClinVar

Aliases tab displays HGVS names representing the variant placements and allele changes on genomic, transcript and protein sequences, per allele. HGVS name is an expression for reporting sequence accession and version, sequence type, position, and allele change. The column "Note" can have two values: "diff" means that there is a difference between the reference allele (variation interval) at the placement reported in HGVS name and the reference alleles reported in other HGVS names, and "rev" means that the sequence of this variation interval at the placement reported in HGVS name is in reverse orientation to the sequence(s) of this variation in other HGVS names not labeled as "rev".

Placement	A=	ins(CA)₇TA	ins(CA)₆TA	ins(CA)₅TA	ins(CA)₃TA	insCACATA	insCATA
GRCh38.p14 chr 1	NC_000001.11:g.154426109=	NC_000001.11:g.154426109AC[7]ATA[1]	NC_000001.11:g.154426109AC[6]ATA[1]	NC_000001.11:g.154426109AC[5]ATA[1]	NC_000001.11:g.154426109AC[3]ATA[1]	NC_000001.11:g.154426109AC[2]ATA[1]	NC_000001.11:g.154426109_154426110insCATA
GRCh37.p13 chr 1	NC_000001.10:g.154398585=	NC_000001.10:g.154398585AC[7]ATA[1]	NC_000001.10:g.154398585AC[6]ATA[1]	NC_000001.10:g.154398585AC[5]ATA[1]	NC_000001.10:g.154398585AC[3]ATA[1]	NC_000001.10:g.154398585AC[2]ATA[1]	NC_000001.10:g.154398585_154398586insCATA
IL6R RefSeqGene	NG_012087.1:g.25917=	NG_012087.1:g.25917AC[7]ATA[1]	NG_012087.1:g.25917AC[6]ATA[1]	NG_012087.1:g.25917AC[5]ATA[1]	NG_012087.1:g.25917AC[3]ATA[1]	NG_012087.1:g.25917AC[2]ATA[1]	NG_012087.1:g.25917_25918insCATA
IL6R transcript variant 1	NM_000565.3:c.86-3087=	NM_000565.3:c.86-3087_86-3086insCACACACACACACATA	NM_000565.3:c.86-3087_86-3086insCACACACACACATA	NM_000565.3:c.86-3087_86-3086insCACACACACATA	NM_000565.3:c.86-3087_86-3086insCACACATA	NM_000565.3:c.86-3087_86-3086insCACATA	NM_000565.3:c.86-3087_86-3086insCATA
IL6R transcript variant 1	NM_000565.4:c.86-3087=	NM_000565.4:c.86-3087_86-3086insCACACACACACACATA	NM_000565.4:c.86-3087_86-3086insCACACACACACATA	NM_000565.4:c.86-3087_86-3086insCACACACACATA	NM_000565.4:c.86-3087_86-3086insCACACATA	NM_000565.4:c.86-3087_86-3086insCACATA	NM_000565.4:c.86-3087_86-3086insCATA
IL6R transcript variant 3	NM_001206866.1:c.86-3087=	NM_001206866.1:c.86-3087_86-3086insCACACACACACACATA	NM_001206866.1:c.86-3087_86-3086insCACACACACACATA	NM_001206866.1:c.86-3087_86-3086insCACACACACATA	NM_001206866.1:c.86-3087_86-3086insCACACATA	NM_001206866.1:c.86-3087_86-3086insCACATA	NM_001206866.1:c.86-3087_86-3086insCATA
IL6R transcript variant 3	NM_001206866.2:c.86-3087=	NM_001206866.2:c.86-3087_86-3086insCACACACACACACATA	NM_001206866.2:c.86-3087_86-3086insCACACACACACATA	NM_001206866.2:c.86-3087_86-3086insCACACACACATA	NM_001206866.2:c.86-3087_86-3086insCACACATA	NM_001206866.2:c.86-3087_86-3086insCACATA	NM_001206866.2:c.86-3087_86-3086insCATA
IL6R transcript variant 4	NM_001382769.1:c.86-3087=	NM_001382769.1:c.86-3087_86-3086insCACACACACACACATA	NM_001382769.1:c.86-3087_86-3086insCACACACACACATA	NM_001382769.1:c.86-3087_86-3086insCACACACACATA	NM_001382769.1:c.86-3087_86-3086insCACACATA	NM_001382769.1:c.86-3087_86-3086insCACATA	NM_001382769.1:c.86-3087_86-3086insCATA
IL6R transcript variant 5	NM_001382770.1:c.86-3087=	NM_001382770.1:c.86-3087_86-3086insCACACACACACACATA	NM_001382770.1:c.86-3087_86-3086insCACACACACACATA	NM_001382770.1:c.86-3087_86-3086insCACACACACATA	NM_001382770.1:c.86-3087_86-3086insCACACATA	NM_001382770.1:c.86-3087_86-3086insCACATA	NM_001382770.1:c.86-3087_86-3086insCATA
IL6R transcript variant 6	NM_001382771.1:c.86-3087=	NM_001382771.1:c.86-3087_86-3086insCACACACACACACATA	NM_001382771.1:c.86-3087_86-3086insCACACACACACATA	NM_001382771.1:c.86-3087_86-3086insCACACACACATA	NM_001382771.1:c.86-3087_86-3086insCACACATA	NM_001382771.1:c.86-3087_86-3086insCACATA	NM_001382771.1:c.86-3087_86-3086insCATA
IL6R transcript variant 7	NM_001382772.1:c.86-3087=	NM_001382772.1:c.86-3087_86-3086insCACACACACACACATA	NM_001382772.1:c.86-3087_86-3086insCACACACACACATA	NM_001382772.1:c.86-3087_86-3086insCACACACACATA	NM_001382772.1:c.86-3087_86-3086insCACACATA	NM_001382772.1:c.86-3087_86-3086insCACATA	NM_001382772.1:c.86-3087_86-3086insCATA
IL6R transcript variant 8	NM_001382773.1:c.86-3087=	NM_001382773.1:c.86-3087_86-3086insCACACACACACACATA	NM_001382773.1:c.86-3087_86-3086insCACACACACACATA	NM_001382773.1:c.86-3087_86-3086insCACACACACATA	NM_001382773.1:c.86-3087_86-3086insCACACATA	NM_001382773.1:c.86-3087_86-3086insCACATA	NM_001382773.1:c.86-3087_86-3086insCATA
IL6R transcript variant 9	NM_001382774.1:c.86-3087=	NM_001382774.1:c.86-3087_86-3086insCACACACACACACATA	NM_001382774.1:c.86-3087_86-3086insCACACACACACATA	NM_001382774.1:c.86-3087_86-3086insCACACACACATA	NM_001382774.1:c.86-3087_86-3086insCACACATA	NM_001382774.1:c.86-3087_86-3086insCACATA	NM_001382774.1:c.86-3087_86-3086insCATA
IL6R transcript variant 2	NM_181359.2:c.86-3087=	NM_181359.2:c.86-3087_86-3086insCACACACACACACATA	NM_181359.2:c.86-3087_86-3086insCACACACACACATA	NM_181359.2:c.86-3087_86-3086insCACACACACATA	NM_181359.2:c.86-3087_86-3086insCACACATA	NM_181359.2:c.86-3087_86-3086insCACATA	NM_181359.2:c.86-3087_86-3086insCATA
IL6R transcript variant 2	NM_181359.3:c.86-3087=	NM_181359.3:c.86-3087_86-3086insCACACACACACACATA	NM_181359.3:c.86-3087_86-3086insCACACACACACATA	NM_181359.3:c.86-3087_86-3086insCACACACACATA	NM_181359.3:c.86-3087_86-3086insCACACATA	NM_181359.3:c.86-3087_86-3086insCACATA	NM_181359.3:c.86-3087_86-3086insCATA
IL6R transcript variant X1	XM_005245138.1:c.23-3087=	XM_005245138.1:c.23-3087_23-3086insCACACACACACACATA	XM_005245138.1:c.23-3087_23-3086insCACACACACACATA	XM_005245138.1:c.23-3087_23-3086insCACACACACATA	XM_005245138.1:c.23-3087_23-3086insCACACATA	XM_005245138.1:c.23-3087_23-3086insCACATA	XM_005245138.1:c.23-3087_23-3086insCATA
IL6R transcript variant X6	XM_005245139.1:c.86-3087=	XM_005245139.1:c.86-3087_86-3086insCACACACACACACATA	XM_005245139.1:c.86-3087_86-3086insCACACACACACATA	XM_005245139.1:c.86-3087_86-3086insCACACACACATA	XM_005245139.1:c.86-3087_86-3086insCACACATA	XM_005245139.1:c.86-3087_86-3086insCACATA	XM_005245139.1:c.86-3087_86-3086insCATA
IL6R transcript variant X8	XM_005245139.2:c.86-3087=	XM_005245139.2:c.86-3087_86-3086insCACACACACACACATA	XM_005245139.2:c.86-3087_86-3086insCACACACACACATA	XM_005245139.2:c.86-3087_86-3086insCACACACACATA	XM_005245139.2:c.86-3087_86-3086insCACACATA	XM_005245139.2:c.86-3087_86-3086insCACATA	XM_005245139.2:c.86-3087_86-3086insCATA
IL6R transcript variant X4	XM_005245140.1:c.86-3087=	XM_005245140.1:c.86-3087_86-3086insCACACACACACACATA	XM_005245140.1:c.86-3087_86-3086insCACACACACACATA	XM_005245140.1:c.86-3087_86-3086insCACACACACATA	XM_005245140.1:c.86-3087_86-3086insCACACATA	XM_005245140.1:c.86-3087_86-3086insCACATA	XM_005245140.1:c.86-3087_86-3086insCATA
IL6R transcript variant X1	XM_017001199.2:c.86-3087=	XM_017001199.2:c.86-3087_86-3086insCACACACACACACATA	XM_017001199.2:c.86-3087_86-3086insCACACACACACATA	XM_017001199.2:c.86-3087_86-3086insCACACACACATA	XM_017001199.2:c.86-3087_86-3086insCACACATA	XM_017001199.2:c.86-3087_86-3086insCACATA	XM_017001199.2:c.86-3087_86-3086insCATA
IL6R transcript variant X2	XM_047419648.1:c.23-3087=	XM_047419648.1:c.23-3087_23-3086insCACACACACACACATA	XM_047419648.1:c.23-3087_23-3086insCACACACACACATA	XM_047419648.1:c.23-3087_23-3086insCACACACACATA	XM_047419648.1:c.23-3087_23-3086insCACACATA	XM_047419648.1:c.23-3087_23-3086insCACATA	XM_047419648.1:c.23-3087_23-3086insCATA
IL6R transcript variant X3	XM_047419649.1:c.23-3087=	XM_047419649.1:c.23-3087_23-3086insCACACACACACACATA	XM_047419649.1:c.23-3087_23-3086insCACACACACACATA	XM_047419649.1:c.23-3087_23-3086insCACACACACATA	XM_047419649.1:c.23-3087_23-3086insCACACATA	XM_047419649.1:c.23-3087_23-3086insCACATA	XM_047419649.1:c.23-3087_23-3086insCATA
IL6R transcript variant X4	XM_047419650.1:c.23-3087=	XM_047419650.1:c.23-3087_23-3086insCACACACACACACATA	XM_047419650.1:c.23-3087_23-3086insCACACACACACATA	XM_047419650.1:c.23-3087_23-3086insCACACACACATA	XM_047419650.1:c.23-3087_23-3086insCACACATA	XM_047419650.1:c.23-3087_23-3086insCACATA	XM_047419650.1:c.23-3087_23-3086insCATA
IL6R transcript variant X5	XM_047419654.1:c.86-3087=	XM_047419654.1:c.86-3087_86-3086insCACACACACACACATA	XM_047419654.1:c.86-3087_86-3086insCACACACACACATA	XM_047419654.1:c.86-3087_86-3086insCACACACACATA	XM_047419654.1:c.86-3087_86-3086insCACACATA	XM_047419654.1:c.86-3087_86-3086insCACATA	XM_047419654.1:c.86-3087_86-3086insCATA
IL6R transcript variant X6	XM_047419655.1:c.86-3087=	XM_047419655.1:c.86-3087_86-3086insCACACACACACACATA	XM_047419655.1:c.86-3087_86-3086insCACACACACACATA	XM_047419655.1:c.86-3087_86-3086insCACACACACATA	XM_047419655.1:c.86-3087_86-3086insCACACATA	XM_047419655.1:c.86-3087_86-3086insCACATA	XM_047419655.1:c.86-3087_86-3086insCATA
IL6R transcript variant X7	XM_047419656.1:c.86-3087=	XM_047419656.1:c.86-3087_86-3086insCACACACACACACATA	XM_047419656.1:c.86-3087_86-3086insCACACACACACATA	XM_047419656.1:c.86-3087_86-3086insCACACACACATA	XM_047419656.1:c.86-3087_86-3086insCACACATA	XM_047419656.1:c.86-3087_86-3086insCACATA	XM_047419656.1:c.86-3087_86-3086insCATA
IL6R transcript variant X9	XM_047419657.1:c.86-3087=	XM_047419657.1:c.86-3087_86-3086insCACACACACACACATA	XM_047419657.1:c.86-3087_86-3086insCACACACACACATA	XM_047419657.1:c.86-3087_86-3086insCACACACACATA	XM_047419657.1:c.86-3087_86-3086insCACACATA	XM_047419657.1:c.86-3087_86-3086insCACATA	XM_047419657.1:c.86-3087_86-3086insCATA

Submissions tab displays variations originally submitted to dbSNP, now supporting this RefSNP cluster (rs). We display Submitter handle, Submission identifier, Date and Build number, when the submission appeared for the first time. Direct submissions to dbSNP have Submission ID in the form of an ss-prefixed number (ss#). Other supporting variations are listed in the table without ss#.

2 SubSNP, 3 Frequency submissions

No	Submitter	Submission ID	Date (Build)
1	GNOMAD	ss4003716070	Apr 25, 2021 (155)
2	GNOMAD	ss4003716071	Apr 25, 2021 (155)
3	gnomAD - Genomes Submission ignored due to conflicting rows: Row 27019807 (NC_000001.11:154426108::ACACACACACACACAT 2/122204) Row 27019808 (NC_000001.11:154426108::ACACACACACAT 1/122204)	-	Apr 25, 2021 (155)
4	gnomAD - Genomes Submission ignored due to conflicting rows: Row 27019807 (NC_000001.11:154426108::ACACACACACACACAT 2/122204) Row 27019808 (NC_000001.11:154426108::ACACACACACAT 1/122204)	-	Apr 25, 2021 (155)
5	ALFA	NC_000001.11 - 154426109	Apr 25, 2021 (155)

History tab displays RefSNPs (Associated ID) from previous builds (Build) that now support the current RefSNP, and the dates, when the history was updated for each Associated ID (History Updated).

Added to this RefSNP Cluster:

Submission IDs	Observation SPDI	Canonical SPDI	Source RSIDs
ss4003716070	NC_000001.11:154426108::ACACACACAC… NC_000001.11:154426108::ACACACACACACACAT	NC_000001.11:154426108:A:ACACACACA… NC_000001.11:154426108:A:ACACACACACACACATA	(self)
730768796	NC_000001.11:154426108:A:ACACACACA… NC_000001.11:154426108:A:ACACACACACACACATA	NC_000001.11:154426108:A:ACACACACA… NC_000001.11:154426108:A:ACACACACACACACATA	(self)
730768796	NC_000001.11:154426108:A:ACACACACA… NC_000001.11:154426108:A:ACACACACACACATA	NC_000001.11:154426108:A:ACACACACA… NC_000001.11:154426108:A:ACACACACACACATA	(self)
ss4003716071	NC_000001.11:154426108::ACACACACAC… NC_000001.11:154426108::ACACACACACAT	NC_000001.11:154426108:A:ACACACACA… NC_000001.11:154426108:A:ACACACACACATA	(self)
730768796	NC_000001.11:154426108:A:ACACACACA… NC_000001.11:154426108:A:ACACACACACATA	NC_000001.11:154426108:A:ACACACACA… NC_000001.11:154426108:A:ACACACACACATA	(self)
730768796	NC_000001.11:154426108:A:ACACACATA	NC_000001.11:154426108:A:ACACACATA	(self)
730768796	NC_000001.11:154426108:A:ACACATA	NC_000001.11:154426108:A:ACACATA	(self)
730768796	NC_000001.11:154426108:A:ACATA	NC_000001.11:154426108:A:ACATA	(self)

Removed from this RefSNP Cluster:

Submission IDs	Observation SPDI	Canonical SPDI	Destination RSIDs
ss3092114690	NC_000001.11:154426108::ACAT	NC_000001.11:154426108:A:ACATA

Publications tab displays PubMed articles citing the variation as a listing of PMID, Title, Author, Year, Journal, ordered by Year, descending.

No publications for rs1491495244

The Flanks tab provides retrieving flanking sequences of a SNP on all molecules that have placements.

Genome context:

Select flank length:

Genomic regions, transcripts, and products
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NCBI Graphical Sequence Viewer display of the genomic region, transcripts and protein products for the reported RefSNP (rs).
Use the zoom option to view the nucleotides around the RefSNP and find other neighboring RefSNPs.
Visit Sequence Viewer for help with navigating inside the display and modifying the selection of displayed data tracks.

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dbSNP Short Genetic Variations

Welcome to the Reference SNP (rs) Report

Reference SNP (rs) Report

rs1491495244