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    PXMT1 S-adenosyl-L-methionine-dependent methyltransferases superfamily protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 842988, updated on 18-Sep-2024

    Summary

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    Official Symbol
    PXMT1
    Official Full Name
    S-adenosyl-L-methionine-dependent methyltransferases superfamily protein
    Primary source
    TAIR:AT1G66700
    Locus tag
    AT1G66700
    See related
    Araport:AT1G66700
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F4N21.16; F4N21_16
    Summary
    A member of the Arabidopsis SABATH methyltransferase gene family. Encodes PXMT1, a methyltransferase that methylates 1,7-paraxanthine.
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    Genomic context

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    See PXMT1 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    3
    Sequence:
    Chromosome: 1; NC_003070.9 (24873206..24874766, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene S-adenosyl-L-methionine-dependent methyltransferases superfamily protein Neighboring gene S-adenosyl-L-methionine-dependent methyltransferases superfamily protein Neighboring gene miscRNA Neighboring gene S-adenosyl-L-methionine-dependent methyltransferases superfamily protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The phenotypic and molecular assessment of the non-conserved Arabidopsis MICRORNA163/S-ADENOSYL-METHYLTRANSFERASE regulatory module during biotic stress. Litholdo CG Jr, et al. Mol Genet Genomics, 2018 Apr. PMID 29196849
    2. Regulation of miR163 and its targets in defense against Pseudomonas syringae in Arabidopsis thaliana. Chow HT, et al. Sci Rep, 2017 Apr 12. PMID 28401908, Free PMC Article
    3. Light-Inducible MiR163 Targets PXMT1 Transcripts to Promote Seed Germination and Primary Root Elongation in Arabidopsis. Chung PJ, et al. Plant Physiol, 2016 Mar. PMID 26768601, Free PMC Article
    4. cis- and trans-Regulation of miR163 and target genes confers natural variation of secondary metabolites in two Arabidopsis species and their allopolyploids. Ng DW, et al. Plant Cell, 2011 May. PMID 21602291, Free PMC Article
    5. An Arabidopsis thaliana gene for methylsalicylate biosynthesis, identified by a biochemical genomics approach, has a role in defense. Chen F, et al. Plant J, 2003 Dec. PMID 14617060

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. S-adenosyl-L-methionine-dependent methyltransferases PXMT transcript abundance indicate that the expression level of the miR163 target gene largely scaled in accordance with miR163 abundance.
      Title: The phenotypic and molecular assessment of the non-conserved Arabidopsis MICRORNA163/S-ADENOSYL-METHYLTRANSFERASE regulatory module during biotic stress.
    2. Results indicate that microRNA miR163 targets methyltransferase PXMT1 mRNA to promote seed germination and modulate root architecture during early development of seedlings.
      Title: Light-Inducible MiR163 Targets PXMT1 Transcripts to Promote Seed Germination and Primary Root Elongation in Arabidopsis.
    Submit: New GeneRIF Correction

    General gene information

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    NM_105341.5
    NM_202367.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables S-adenosylmethionine-dependent methyltransferase activity IDA
    Inferred from Direct Assay
    more info
    		  
    Process Evidence Code Pubs
    involved_in defense response to bacterium IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in miRNA-mediated post-transcriptional gene silencing IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in regulation of root development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of seed germination IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of seedling development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in response to bacterium IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in response to herbivore IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in response to light stimulus IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in response to molecule of fungal origin IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in response to salicylic acid IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    S-adenosyl-L-methionine-dependent methyltransferases superfamily protein
    NP_564881.3
    • PXMT1; CONTAINS InterPro DOMAIN/s: SAM dependent carboxyl methyltransferase (InterPro:IPR005299); BEST Arabidopsis thaliana protein match is: S-adenosyl-L-methionine-dependent methyltransferases superfamily protein (TAIR:AT1G66690.1); Has 857 Blast hits to 852 proteins in 114 species: Archae - 0; Bacteria - 51; Metazoa - 9; Fungi - 5; Plants - 706; Viruses - 0; Other Eukaryotes - 86 (source: NCBI BLink).
    NP_974096.1
    • PXMT1; CONTAINS InterPro DOMAIN/s: SAM dependent carboxyl methyltransferase (InterPro:IPR005299); BEST Arabidopsis thaliana protein match is: S-adenosyl-L-methionine-dependent methyltransferases superfamily protein (TAIR:AT1G66690.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      24873206..24874766 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_105341.5 → NP_564881.3  S-adenosyl-L-methionine-dependent methyltransferases superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_564881.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      F4HPZ7, Q8LGA6, Q941F2, Q9C9M3
      UniProtKB/TrEMBL
      A0A178W739, A0A5S9WQ82
      Conserved Domains (1) summary
      pfam03492
      Location:38 → 351
      Methyltransf_7; SAM dependent carboxyl methyltransferase

    2. NM_202367.3 → NP_974096.1  S-adenosyl-L-methionine-dependent methyltransferases superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_974096.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9C9M3
      Conserved Domains (1) summary
      pfam03492
      Location:39 → 243
      Methyltransf_7; SAM dependent carboxyl methyltransferase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9C9M3.1

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