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    NEK1 NIMA-related serine/threonine kinase 1 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 841893, updated on 18-Sep-2024

    Summary

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    Official Symbol
    NEK1
    Official Full Name
    NIMA-related serine/threonine kinase 1
    Primary source
    TAIR:AT1G54510
    Locus tag
    AT1G54510
    See related
    Araport:AT1G54510
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATNEK1; F20D21.32; F20D21_32; NIMA-RELATED KINASE1; NIMA-related serine/threonine kinase 1
    Summary
    Encodes AtNEK1, a member of the NIMA-related serine/threonine kinases (Neks) that have been linked to cell-cycle regulation in fungi and mammals. Plant Neks might be involved in plant development processes.
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    Genomic context

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    See NEK1 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    16
    Sequence:
    Chromosome: 1; NC_003070.9 (20358319..20362624, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene exoribonuclease 4 Neighboring gene Rubredoxin-like superfamily protein Neighboring gene myelin-associated oligodendrocyte basic protein Neighboring gene Calcium-binding EF hand family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    General gene information

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    NM_001198295.1
    NM_001198296.1
    NM_001333653.1
    NM_001333654.1

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within phosphorylation ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  
    located_in plasma membrane ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    NIMA-related serine/threonine kinase 1
    NP_001185224.1
    • NIMA-related serine/threonine kinase 1 (NEK1); FUNCTIONS IN: protein serine/threonine kinase activity, protein kinase activity, kinase activity, ATP binding; INVOLVED IN: protein amino acid phosphorylation; LOCATED IN: cellular_component unknown; EXPRESSED IN: 18 plant structures; EXPRESSED DURING: 7 growth stages; CONTAINS InterPro DOMAIN/s: Protein kinase, ATP binding site (InterPro:IPR017441), Protein kinase, catalytic domain (InterPro:IPR000719), Serine/threonine-protein kinase domain (InterPro:IPR002290), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271); BEST Arabidopsis thaliana protein match is: NIMA-related kinase 2 (TAIR:AT3G04810.2).
    NP_001319226.1
    • NIMA-related serine/threonine kinase 1 (NEK1); FUNCTIONS IN: protein serine/threonine kinase activity, protein kinase activity, kinase activity, ATP binding; INVOLVED IN: protein amino acid phosphorylation; LOCATED IN: cellular_component unknown; EXPRESSED IN: 18 plant structures; EXPRESSED DURING: 7 growth stages; CONTAINS InterPro DOMAIN/s: Protein kinase, ATP binding site (InterPro:IPR017441), Protein kinase, catalytic domain (InterPro:IPR000719), Serine/threonine-protein kinase domain (InterPro:IPR002290), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271); BEST Arabidopsis thaliana protein match is: NIMA-related kinase 2 (TAIR:AT3G04810.2).
    NP_175853.1
    • NIMA-related serine/threonine kinase 1 (NEK1); FUNCTIONS IN: protein serine/threonine kinase activity, protein kinase activity, kinase activity, ATP binding; INVOLVED IN: protein amino acid phosphorylation; LOCATED IN: cellular_component unknown; EXPRESSED IN: 18 plant structures; EXPRESSED DURING: 7 growth stages; CONTAINS InterPro DOMAIN/s: Protein kinase, ATP binding site (InterPro:IPR017441), Protein kinase, catalytic domain (InterPro:IPR000719), Serine/threonine-protein kinase domain (InterPro:IPR002290), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271); BEST Arabidopsis thaliana protein match is: NIMA-related kinase 2 (TAIR:AT3G04810.2); Has 126786 Blast hits to 124499 proteins in 4540 species: Archae - 112; Bacteria - 14456; Metazoa - 47155; Fungi - 12426; Plants - 31152; Viruses - 487; Other Eukaryotes - 20998 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      20358319..20362624 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_104329.5 → NP_175853.1  NIMA-related serine/threonine kinase 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_175853.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9SLI2, Q9SLI3
      UniProtKB/TrEMBL
      A0A5S9WPN3, A0A654EJW0
      Conserved Domains (1) summary
      cd08215
      Location:3 → 258
      STKc_Nek; Catalytic domain of the Serine/Threonine Kinase, Never In Mitosis gene A (NIMA)-related kinase

    2. NM_001198295.1 → NP_001185224.1  NIMA-related serine/threonine kinase 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001185224.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9SLI2, Q9SLI3
      UniProtKB/TrEMBL
      A0A5S9WPN3, A0A654EJW0
      Conserved Domains (1) summary
      cd08215
      Location:3 → 258
      STKc_Nek; Catalytic domain of the Serine/Threonine Kinase, Never In Mitosis gene A (NIMA)-related kinase

    3. NM_001333653.1 → NP_001319226.1  NIMA-related serine/threonine kinase 1 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9SLI2, Q9SLI3
      UniProtKB/TrEMBL
      A0A5S9WPN3, A0A654EJW0
      Conserved Domains (1) summary
      cd08215
      Location:3 → 258
      STKc_Nek; Catalytic domain of the Serine/Threonine Kinase, Never In Mitosis gene A (NIMA)-related kinase

    4. NM_001198296.1 → NP_001185225.1  NIMA-related serine/threonine kinase 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001185225.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9SLI2, Q9SLI3
      UniProtKB/TrEMBL
      A0A5S9WPN3, A0A654EJW0
      Conserved Domains (1) summary
      cd08215
      Location:3 → 258
      STKc_Nek; Catalytic domain of the Serine/Threonine Kinase, Never In Mitosis gene A (NIMA)-related kinase

    5. NM_001333654.1 → NP_001322059.1  NIMA-related serine/threonine kinase 1 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178WLV4, A0A1P8AST4
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9SLI2.2

    Gene LinkOut

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