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    Signal recognition particle, SRP54 subunit protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 841312, updated on 7-Oct-2024

    Summary

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    Official Full Name
    Signal recognition particle, SRP54 subunit protein
    Primary source
    TAIR:AT1G48900
    Locus tag
    AT1G48900
    See related
    Araport:AT1G48900
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F27K7.8; F27K7_8
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    Genomic context

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    Location:
    chromosome: 1
    Exon count:
    9
    Sequence:
    Chromosome: 1; NC_003070.9 (18084715..18087934, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene TRICHOME BIREFRINGENCE-LIKE 7 Neighboring gene pseudo Neighboring gene Flavin-containing monooxygenase family protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The role of chloroplast SRP54 domains and its C-terminal tail region in post- and co-translational protein transport in vivo. Bischoff A, et al. J Exp Bot, 2024 Sep 27. PMID 38989593, Free PMC Article
    2. Ribosome-Associated Chloroplast SRP54 Enables Efficient Cotranslational Membrane Insertion of Key Photosynthetic Proteins. Hristou A, et al. Plant Cell, 2019 Nov. PMID 31444312, Free PMC Article
    3. Chloroplast SRP54 Was Recruited for Posttranslational Protein Transport via Complex Formation with Chloroplast SRP43 during Land Plant Evolution. Dünschede B, et al. J Biol Chem, 2015 May 22. PMID 25833951, Free PMC Article
    4. Identification of ubiquitinated proteins in Arabidopsis. Manzano C, et al. Plant Mol Biol, 2008 Sep. PMID 18535787
    5. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The role of chloroplast SRP54 domains and its C-terminal tail region in post- and co-translational protein transport in vivo.
      Title: The role of chloroplast SRP54 domains and its C-terminal tail region in post- and co-translational protein transport in vivo.
    2. chloroplast signal recognition particle subunit (cpSRP54) is required for efficient cotranslational targeting of several central photosynthetic proteins, such as the PSII PsbA (D1) subunit, in Arabidopsis (Arabidopsis thaliana).
      Title: Ribosome-Associated Chloroplast SRP54 Enables Efficient Cotranslational Membrane Insertion of Key Photosynthetic Proteins.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_001084221.1
    NM_103783.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables 7S RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables GTPase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in SRP-dependent cotranslational protein targeting to membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    Signal recognition particle, SRP54 subunit protein
    NP_001077690.1
    • Signal recognition particle, SRP54 subunit protein; FUNCTIONS IN: 7S RNA binding, mRNA binding, nucleoside-triphosphatase activity, GTP binding, nucleotide binding; INVOLVED IN: SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition, SRP-dependent cotranslational protein targeting to membrane; LOCATED IN: signal recognition particle, signal recognition particle, endoplasmic reticulum targeting; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: ATPase, AAA+ type, core (InterPro:IPR003593), Signal recognition particle, SRP54 subunit, helical bundle (InterPro:IPR013822), Signal recognition particle, SRP54 subunit, M-domain (InterPro:IPR004125), Signal recognition particle, SRP54 subunit (InterPro:IPR006325), Signal recognition particle, SRP54 subunit, GTPase (InterPro:IPR000897); BEST Arabidopsis thaliana protein match is: signal recognition particle 54 kDa subunit (TAIR:AT1G15310.1); Has 17287 Blast hits to 17282 proteins in 2918 species: Archae - 472; Bacteria - 10591; Metazoa - 363; Fungi - 288; Plants - 279; Viruses - 1; Other Eukaryotes - 5293 (source: NCBI BLink).
    NP_564535.1
    • Signal recognition particle, SRP54 subunit protein; FUNCTIONS IN: 7S RNA binding, mRNA binding, nucleoside-triphosphatase activity, GTP binding, nucleotide binding; INVOLVED IN: SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition, SRP-dependent cotranslational protein targeting to membrane; LOCATED IN: signal recognition particle, signal recognition particle, endoplasmic reticulum targeting; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: ATPase, AAA+ type, core (InterPro:IPR003593), Signal recognition particle, SRP54 subunit, helical bundle (InterPro:IPR013822), Signal recognition particle, SRP54 subunit, M-domain (InterPro:IPR004125), Signal recognition particle, SRP54 subunit (InterPro:IPR006325), Signal recognition particle, SRP54 subunit, GTPase (InterPro:IPR000897); BEST Arabidopsis thaliana protein match is: Signal recognition particle, SRP54 subunit protein (TAIR:AT5G49500.1); Has 17579 Blast hits to 17572 proteins in 2934 species: Archae - 472; Bacteria - 10667; Metazoa - 363; Fungi - 296; Plants - 287; Viruses - 1; Other Eukaryotes - 5493 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      18084715..18087934 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_103783.2 → NP_564535.1  Signal recognition particle, SRP54 subunit protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_564535.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P49967, Q93W49, Q9FVP9
      UniProtKB/TrEMBL
      A0A178WMZ2, A0A5S9WN31, A0A7G2E2W7
      Conserved Domains (1) summary
      TIGR01425
      Location:2 → 428
      SRP54_euk; signal recognition particle protein SRP54

    2. NM_001084221.1 → NP_001077690.1  Signal recognition particle, SRP54 subunit protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001077690.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A8MSA9, C0Z2C1
      Conserved Domains (4) summary
      TIGR01425
      Location:2 → 418
      SRP54_euk; signal recognition particle protein SRP54
      pfam00448
      Location:102 → 294
      SRP54; SRP54-type protein, GTPase domain
      pfam02881
      Location:6 → 83
      SRP54_N; SRP54-type protein, helical bundle domain
      pfam02978
      Location:327 → 417
      SRP_SPB; Signal peptide binding domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P49967.2

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