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    uncharacterized protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 841102, updated on 18-Sep-2024

    Summary

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    Official Full Name
    uncharacterized protein
    Primary source
    TAIR:AT1G45688
    Locus tag
    AT1G45688
    See related
    Araport:AT1G45688
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F2G19.25; F2G19_25
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    Genomic context

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    Location:
    chromosome: 1
    Exon count:
    2
    Sequence:
    Chromosome: 1; NC_003070.9 (17191362..17193314)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene photosystem I light harvesting complex protein 5 Neighboring gene WEAK CHLOROPLAST MOVEMENT UNDER BLUE LIGHT-like protein (DUF827) Neighboring gene receptor like protein 6 Neighboring gene pseudo Neighboring gene pseudo

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The companion of cellulose synthase 1 confers salt tolerance through a Tau-like mechanism in plants. Kesten C, et al. Nat Commun, 2019 Feb 20. PMID 30787279, Free PMC Article
    2. A Mechanism for Sustained Cellulose Synthesis during Salt Stress. Endler A, et al. Cell, 2015 Sep 10. PMID 26343580
    3. Tip Growth Defective1 interacts with the cellulose synthase complex to regulate cellulose synthesis in Arabidopsis thaliana. Lampugnani ER, et al. PLoS One, 2024. PMID 38358988, Free PMC Article
    4. Large-scale analysis of in vivo phosphorylated membrane proteins by immobilized metal ion affinity chromatography and mass spectrometry. Nühse TS, et al. Mol Cell Proteomics, 2003 Nov. PMID 14506206
    5. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. By NMR and live cell analyses the authors reveal that two neighboring residues in the first hydrophobic binding motif are crucial for the microtubule interaction, which is reminiscent to that of the prominent neuropathology-related protein Tau, indicating evolutionary convergence of MAP functions across animal and plant cells. [companion of cellulose synthase 1]
      Title: The companion of cellulose synthase 1 confers salt tolerance through a Tau-like mechanism in plants.
    2. Study identified two plant-specific proteins, companion of cellulose synthase 1 and 2 CC1 (At1g45688) and CC2 (AT5G42860) that can interact with the CesA proteins and with microtubules. Mutations of the proteins led to salt-sensitive phenotypes and altered microtubule and CSC behavior in vivo.
      Title: A Mechanism for Sustained Cellulose Synthesis during Salt Stress.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_103600.5
    NM_202253.1

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables microtubule binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables molecular_function ND
    No biological Data available
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in plasma membrane HDA PubMed 
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in trans-Golgi network IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    uncharacterized protein
    NP_564495.1
    • unknown protein; FUNCTIONS IN: molecular_function unknown; INVOLVED IN: biological_process unknown; LOCATED IN: plasma membrane; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; BEST Arabidopsis thaliana protein match is: unknown protein (TAIR:AT5G42860.1); Has 258 Blast hits to 242 proteins in 39 species: Archae - 0; Bacteria - 11; Metazoa - 10; Fungi - 14; Plants - 198; Viruses - 17; Other Eukaryotes - 8 (source: NCBI BLink).
    NP_973982.1
    • unknown protein; FUNCTIONS IN: molecular_function unknown; INVOLVED IN: biological_process unknown; LOCATED IN: plasma membrane; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; BEST Arabidopsis thaliana protein match is: unknown protein (TAIR:AT5G42860.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      17191362..17193314
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_103600.5 → NP_564495.1  uncharacterized protein AT1G45688 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_564495.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178WJL5, A0A5S9WPI9, Q9C636

    2. NM_202253.1 → NP_973982.1  uncharacterized protein AT1G45688 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_973982.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      F4HRE0
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

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