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    WOX14 WUSCHEL related homeobox 14 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 838660, updated on 18-Sep-2024

    Summary

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    Official Symbol
    WOX14
    Official Full Name
    WUSCHEL related homeobox 14
    Primary source
    TAIR:AT1G20700
    Locus tag
    AT1G20700
    See related
    Araport:AT1G20700
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATWOX14; F2D10.19; F2D10_19; WUSCHEL related homeobox 14; WUSCHEL RELATED HOMEOBOX 14
    Summary
    Encodes WOX14, a WUSCHEL-related homeobox gene family member with 65 amino acids in its homeodomain. Proteins in this family contain a sequence of eight residues (TLPLFPMH) downstream of the homeodomain called the WUS box. Functions in the shoot meristem organizing center to maintain the stem cells in an undifferentiated state. WOX4 and WOX14 act downstream of the PXY receptor kinase to regulate plant vascular proliferation independently of any role in vascular organisation.
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    Genomic context

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    See WOX14 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    3
    Sequence:
    Chromosome: 1; NC_003070.9 (7182558..7184056)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene high mobility group B2 Neighboring gene high mobility group B3 Neighboring gene RAD3-like DNA-binding helicase protein Neighboring gene WUSCHEL related homeobox 10

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. WOX14 promotes bioactive gibberellin synthesis and vascular cell differentiation in Arabidopsis. Denis E, et al. Plant J, 2017 May. PMID 28218997
    2. Vascular signalling mediated by ZWILLE potentiates WUSCHEL function during shoot meristem stem cell development in the Arabidopsis embryo. Tucker MR, et al. Development, 2008 Sep. PMID 18653559
    3. WOX4 and WOX14 act downstream of the PXY receptor kinase to regulate plant vascular proliferation independently of any role in vascular organisation. Etchells JP, et al. Development, 2013 May. PMID 23578929, Free PMC Article
    4. Enhanced Y1H assays for Arabidopsis. Gaudinier A, et al. Nat Methods, 2011 Oct 30. PMID 22037706, Free PMC Article
    5. Promoter-based integration in plant defense regulation. Li B, et al. Plant Physiol, 2014 Dec. PMID 25352272, Free PMC Article

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. WOX4 acts redundantly with WOX14 in the regulation of vascular cell division, but not in regulating vascular organisation
      Title: WOX4 and WOX14 act downstream of the PXY receptor kinase to regulate plant vascular proliferation independently of any role in vascular organisation.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_001332460.1
    NM_001332461.1
    NM_101922.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA-binding transcription factor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables transcription cis-regulatory region binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within cell division IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within phloem or xylem histogenesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within primary shoot apical meristem specification IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    WUSCHEL related homeobox 14
    NP_173493.2
    • WUSCHEL related homeobox 14 (WOX14); CONTAINS InterPro DOMAIN/s: Homeobox (InterPro:IPR001356), Homeodomain-like (InterPro:IPR009057), Homeodomain-related (InterPro:IPR012287); BEST Arabidopsis thaliana protein match is: WUSCHEL related homeobox 10 (TAIR:AT1G20710.1); Has 657 Blast hits to 657 proteins in 86 species: Archae - 0; Bacteria - 0; Metazoa - 109; Fungi - 12; Plants - 530; Viruses - 0; Other Eukaryotes - 6 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      7182558..7184056
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_101922.3 → NP_173493.2  WUSCHEL related homeobox 14 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_173493.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9LM84
      UniProtKB/TrEMBL
      A0A178W4J5, A0A5S9VCZ8
      Conserved Domains (1) summary
      pfam00046
      Location:94 → 152
      Homeobox; Homeobox domain

    2. NM_001332460.1 → NP_001322716.1  WUSCHEL related homeobox 14 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8AUU8

    3. NM_001332461.1 → NP_001322715.1  WUSCHEL related homeobox 14 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178W4J5, A0A1P8AUV1, A0A5S9VCZ8
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9LM84.1

    Gene LinkOut

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