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    GAPA-2 glyceraldehyde 3-phosphate dehydrogenase A subunit 2 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 837848, updated on 18-Sep-2024

    Summary

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    Official Symbol
    GAPA-2
    Official Full Name
    glyceraldehyde 3-phosphate dehydrogenase A subunit 2
    Primary source
    TAIR:AT1G12900
    Locus tag
    AT1G12900
    See related
    Araport:AT1G12900
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F13K23.15; F13K23_15; glyceraldehyde 3-phosphate dehydrogenase A subunit 2
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    Genomic context

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    See GAPA-2 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    5
    Sequence:
    Chromosome: 1; NC_003070.9 (4392438..4394454, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene nudix hydrolase homolog 12 Neighboring gene ncRNA Neighboring gene Integrase-type DNA-binding superfamily protein Neighboring gene Transducin/WD40 repeat-like superfamily protein Neighboring gene eukaryotic release factor 1-2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Identification of multiple salicylic acid-binding proteins using two high throughput screens. Manohar M, et al. Front Plant Sci, 2014. PMID 25628632, Free PMC Article
    2. Regulation of Active DNA Demethylation by a Methyl-CpG-Binding Domain Protein in Arabidopsis thaliana. Li Q, et al. PLoS Genet, 2015 May. PMID 25933434, Free PMC Article
    3. Redox Conformation-Specific Protein-Protein Interactions of the 2-Cysteine Peroxiredoxin in Arabidopsis. Liebthal M, et al. Antioxidants (Basel), 2020 Jun 11. PMID 32545358, Free PMC Article
    4. Proteomics of the chloroplast envelope membranes from Arabidopsis thaliana. Ferro M, et al. Mol Cell Proteomics, 2003 May. PMID 12766230
    5. Hydroponic isotope labelling of entire plants (HILEP) for quantitative plant proteomics; an oxidative stress case study. Bindschedler LV, et al. Phytochemistry, 2008 Jul. PMID 18538804

    See all (19) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    NM_001084060.1
    NM_001123804.1
    NM_001198048.1
    NM_101161.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables NAD binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables NADP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables mRNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables salicylic acid binding HDA PubMed 
    Process Evidence Code Pubs
    involved_in glucose metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in reductive pentose-phosphate cycle IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in apoplast HDA PubMed 
    located_in chloroplast HDA PubMed 
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in chloroplast envelope HDA PubMed 
    located_in chloroplast stroma HDA PubMed 
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  
    NOT located_in cytosol RCA
    inferred from Reviewed Computational Analysis
    more info
    		 PubMed 
    located_in extracellular region HDA PubMed 

    General protein information

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    Preferred Names
    glyceraldehyde 3-phosphate dehydrogenase A subunit 2
    NP_001077529.1
    • glyceraldehyde 3-phosphate dehydrogenase A subunit 2 (GAPA-2); FUNCTIONS IN: glyceraldehyde-3-phosphate dehydrogenase activity; INVOLVED IN: glycolysis; LOCATED IN: apoplast, chloroplast, membrane; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain (InterPro:IPR020829), Glyceraldehyde 3-phosphate dehydrogenase subfamily (InterPro:IPR000173), Glyceraldehyde 3-phosphate dehydrogenase family (InterPro:IPR020831), Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain, subgroup (InterPro:IPR020832), Glyceraldehyde 3-phosphate dehydrogenase, active site (InterPro:IPR020830), Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain (InterPro:IPR020828); BEST Arabidopsis thaliana protein match is: glyceraldehyde 3-phosphate dehydrogenase A subunit (TAIR:AT3G26650.1); Has 24213 Blast hits to 24212 proteins in 6137 species: Archae - 36; Bacteria - 10763; Metazoa - 2201; Fungi - 2756; Plants - 3727; Viruses - 0; Other Eukaryotes - 4730 (source: NCBI BLink).
    NP_001117276.1
    • glyceraldehyde 3-phosphate dehydrogenase A subunit 2 (GAPA-2); FUNCTIONS IN: NAD or NADH binding, glyceraldehyde-3-phosphate dehydrogenase activity; INVOLVED IN: oxidation reduction, glycolysis, glucose metabolic process; LOCATED IN: apoplast, chloroplast, membrane; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Glyceraldehyde 3-phosphate dehydrogenase subfamily (InterPro:IPR000173), Glyceraldehyde 3-phosphate dehydrogenase family (InterPro:IPR020831), Glyceraldehyde-3-phosphate dehydrogenase, type I (InterPro:IPR006424), Glyceraldehyde 3-phosphate dehydrogenase, active site (InterPro:IPR020830), Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain (InterPro:IPR020829), Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain, subgroup (InterPro:IPR020832), Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain (InterPro:IPR020828); BEST Arabidopsis thaliana protein match is: glyceraldehyde 3-phosphate dehydrogenase A subunit (TAIR:AT3G26650.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).
    NP_001184977.1
    • glyceraldehyde 3-phosphate dehydrogenase A subunit 2 (GAPA-2); FUNCTIONS IN: NAD or NADH binding, glyceraldehyde-3-phosphate dehydrogenase activity; INVOLVED IN: oxidation reduction, glycolysis, glucose metabolic process; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Glyceraldehyde 3-phosphate dehydrogenase subfamily (InterPro:IPR000173), Glyceraldehyde 3-phosphate dehydrogenase family (InterPro:IPR020831), Glyceraldehyde-3-phosphate dehydrogenase, type I (InterPro:IPR006424), Glyceraldehyde 3-phosphate dehydrogenase, active site (InterPro:IPR020830), Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain (InterPro:IPR020829), Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain, subgroup (InterPro:IPR020832), Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain (InterPro:IPR020828); BEST Arabidopsis thaliana protein match is: glyceraldehyde 3-phosphate dehydrogenase A subunit (TAIR:AT3G26650.1).
    NP_172750.1
    • glyceraldehyde 3-phosphate dehydrogenase A subunit 2 (GAPA-2); FUNCTIONS IN: NAD or NADH binding, glyceraldehyde-3-phosphate dehydrogenase activity; INVOLVED IN: oxidation reduction, glycolysis, glucose metabolic process; LOCATED IN: apoplast, chloroplast stroma, chloroplast, membrane, chloroplast envelope; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Glyceraldehyde 3-phosphate dehydrogenase subfamily (InterPro:IPR000173), Glyceraldehyde 3-phosphate dehydrogenase family (InterPro:IPR020831), Glyceraldehyde-3-phosphate dehydrogenase, type I (InterPro:IPR006424), Glyceraldehyde 3-phosphate dehydrogenase, active site (InterPro:IPR020830), Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain (InterPro:IPR020829), Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain, subgroup (InterPro:IPR020832), Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain (InterPro:IPR020828); BEST Arabidopsis thaliana protein match is: glyceraldehyde 3-phosphate dehydrogenase A subunit (TAIR:AT3G26650.1); Has 24704 Blast hits to 24695 proteins in 6149 species: Archae - 47; Bacteria - 10700; Metazoa - 2230; Fungi - 2778; Plants - 3753; Viruses - 0; Other Eukaryotes - 5196 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      4392438..4394454 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001332055.1 → NP_001321059.1  glyceraldehyde 3-phosphate dehydrogenase A subunit 2 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8APR6, A0A7G2ET00
      Conserved Domains (1) summary
      PLN03096
      Location:48 → 441
      PLN03096; glyceraldehyde-3-phosphate dehydrogenase A; Provisional

    2. NM_101161.3 → NP_172750.1  glyceraldehyde 3-phosphate dehydrogenase A subunit 2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_172750.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      B3H4P2, C0Z2Y9, Q9LPW0
      UniProtKB/TrEMBL
      A0A178WA64, A0A5S9U5M4, A0A7G2ET00
      Conserved Domains (1) summary
      PLN03096
      Location:6 → 399
      PLN03096; glyceraldehyde-3-phosphate dehydrogenase A; Provisional

    3. NM_001084060.1 → NP_001077529.1  glyceraldehyde 3-phosphate dehydrogenase A subunit 2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001077529.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      F4HNZ6
      Conserved Domains (2) summary
      pfam00044
      Location:69 → 134
      Gp_dh_N; Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain
      pfam02800
      Location:139 → 295
      Gp_dh_C; Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain

    4. NM_001123804.1 → NP_001117276.1  glyceraldehyde 3-phosphate dehydrogenase A subunit 2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001117276.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A7G2ET00
      Conserved Domains (3) summary
      PRK07403
      Location:16 → 350
      PRK07403; glyceraldehyde-3-phosphate dehydrogenase; Reviewed
      pfam00044
      Location:16 → 167
      Gp_dh_N; Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain
      pfam02800
      Location:172 → 328
      Gp_dh_C; Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain

    5. NM_001198048.1 → NP_001184977.1  glyceraldehyde 3-phosphate dehydrogenase A subunit 2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001184977.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A7G2ET00
      Conserved Domains (3) summary
      PRK07403
      Location:16 → 350
      PRK07403; glyceraldehyde-3-phosphate dehydrogenase; Reviewed
      pfam00044
      Location:16 → 167
      Gp_dh_N; Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain
      pfam02800
      Location:172 → 328
      Gp_dh_C; Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9LPW0.1

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