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    PPCK1 phosphoenolpyruvate carboxylase kinase 1 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 837387, updated on 18-Sep-2024

    Summary

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    Official Symbol
    PPCK1
    Official Full Name
    phosphoenolpyruvate carboxylase kinase 1
    Primary source
    TAIR:AT1G08650
    Locus tag
    AT1G08650
    See related
    Araport:AT1G08650
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATPPCK1; PHOSPHOENOLPYRUVATE CARBOXYLASE KINASE; phosphoenolpyruvate carboxylase kinase 1; PHOSPHOENOLPYRUVATE CARBOXYLASE KINASE 1
    Summary
    Encodes a phosphoenolpyruvate carboxylase kinase that is expressed at highest levels in leaves. Expression is induced by light.
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    Genomic context

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    See PPCK1 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    3
    Sequence:
    Chromosome: 1; NC_003070.9 (2752124..2753809)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene Transcription factor jumonji (jmj) family protein / zinc finger (C5HC2 type) family protein Neighboring gene threonine aldolase 1 Neighboring gene Chloroplast J-like domain 1 Neighboring gene pseudo Neighboring gene uncharacterized protein Neighboring gene MALE GAMETOPHYTE DEFECTIVE 2 Neighboring gene ENTH/VHS family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The impact of PEPC phosphorylation on growth and development of Arabidopsis thaliana: molecular and physiological characterization of PEPC kinase mutants. Meimoun P, et al. FEBS Lett, 2009 May 19. PMID 19397910
    2. pH and carbon supply control the expression of phosphoenolpyruvate carboxylase kinase genes in Arabidopsis thaliana. Chen ZH, et al. Plant Cell Environ, 2008 Dec. PMID 18771573
    3. Phosphoenolpyruvate carboxylase (PEPC) and PEPC-kinase (PEPC-k) isoenzymes in Arabidopsis thaliana: role in control and abiotic stress conditions. Feria AB, et al. Planta, 2016 Oct. PMID 27306451
    4. Phosphoenolpyruvate carboxylase kinase is a novel protein kinase regulated at the level of expression. Hartwell J, et al. Plant J, 1999 Nov. PMID 10571893
    5. Arabidopsis MAS2, an Essential Gene That Encodes a Homolog of Animal NF-κ B Activating Protein, Is Involved in 45S Ribosomal DNA Silencing. Sánchez-García AB, et al. Plant Cell, 2015 Jul. PMID 26139346, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Phosphoenolpyruvate carboxylase (PEPC) activity was decreased in shoots and roots of ppc2 and ppc3 mutants, and phosphate starvation increased the expression of all PEPC and phosphoenolpyruvate carboxylase kinase genes in shoots, but only PPC3 and PPCK2 in roots
      Title: Phosphoenolpyruvate carboxylase (PEPC) and PEPC-kinase (PEPC-k) isoenzymes in Arabidopsis thaliana: role in control and abiotic stress conditions.
    2. These data establish the PPCk1 gene product as responsible for leaf PEPC phosphorylation in planta and show that the absence of PEPC phosphorylation has pleiotropic consequences on plant metabolism
      Title: The impact of PEPC phosphorylation on growth and development of Arabidopsis thaliana: molecular and physiological characterization of PEPC kinase mutants.
    3. Expression of both PPCK1 and PPCK2 is increased by C availability, but does not respond to N availability. Elevated pH reduces the repression of PPCK gene expression by Pi.
      Title: pH and carbon supply control the expression of phosphoenolpyruvate carboxylase kinase genes in Arabidopsis thaliana.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_001198012.1

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein serine/threonine kinase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within protein phosphorylation IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  
    located_in plasma membrane ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    phosphoenolpyruvate carboxylase kinase 1
    NP_001184941.1
    • phosphoenolpyruvate carboxylase kinase 1 (PPCK1); FUNCTIONS IN: protein serine/threonine kinase activity, kinase activity; INVOLVED IN: protein amino acid phosphorylation; LOCATED IN: cellular_component unknown; EXPRESSED IN: 20 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Protein kinase, ATP binding site (InterPro:IPR017441), Serine/threonine-protein kinase domain (InterPro:IPR002290), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271), Protein kinase, catalytic domain (InterPro:IPR000719), Calcium-dependent protein kinase (InterPro:IPR020642), Calcium/calmodulin-dependent protein kinase-like (InterPro:IPR020636), Tyrosine-protein kinase, catalytic domain (InterPro:IPR020635); BEST Arabidopsis thaliana protein match is: phosphoenolpyruvate carboxylase kinase 2 (TAIR:AT3G04530.1).
    NP_172341.1
    • phosphoenolpyruvate carboxylase kinase 1 (PPCK1); FUNCTIONS IN: protein serine/threonine kinase activity, kinase activity; INVOLVED IN: protein amino acid phosphorylation; LOCATED IN: cellular_component unknown; EXPRESSED IN: 20 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Protein kinase, ATP binding site (InterPro:IPR017441), Protein kinase, catalytic domain (InterPro:IPR000719), Serine/threonine-protein kinase domain (InterPro:IPR002290), Calcium-dependent protein kinase (InterPro:IPR020642), Calcium/calmodulin-dependent protein kinase-like (InterPro:IPR020636), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271); BEST Arabidopsis thaliana protein match is: phosphoenolpyruvate carboxylase kinase 2 (TAIR:AT3G04530.1); Has 121330 Blast hits to 119354 proteins in 3292 species: Archae - 175; Bacteria - 14755; Metazoa - 43495; Fungi - 13131; Plants - 28233; Viruses - 522; Other Eukaryotes - 21019 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      2752124..2753809
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_100738.3 → NP_172341.1  phosphoenolpyruvate carboxylase kinase 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_172341.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9FRS0, Q9SPK4
      UniProtKB/TrEMBL
      A0A178WK88, A0A5S9TB23
      Conserved Domains (1) summary
      cd05117
      Location:14 → 272
      STKc_CAMK; The catalytic domain of CAMK family Serine/Threonine Kinases

    2. NM_001198012.1 → NP_001184941.1  phosphoenolpyruvate carboxylase kinase 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001184941.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178WK88, F4HXN6
      Conserved Domains (2) summary
      smart00220
      Location:15 → 271
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd05117
      Location:14 → 269
      STKc_CAMK; The catalytic domain of CAMK family Serine/Threonine Kinases
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9SPK4.1

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