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    MED22B Surfeit locus protein 5 subunit 22 of Mediator complex [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 837310, updated on 18-Sep-2024

    Summary

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    Official Symbol
    MED22B
    Official Full Name
    Surfeit locus protein 5 subunit 22 of Mediator complex
    Primary source
    TAIR:AT1G07950
    Locus tag
    AT1G07950
    See related
    Araport:AT1G07950
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    T6D22.4; T6D22_4
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    Genomic context

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    See MED22B in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    3
    Sequence:
    Chromosome: 1; NC_003070.9 (2465729..2467165, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene GTP binding Elongation factor Tu family protein Neighboring gene GTP binding Elongation factor Tu family protein Neighboring gene pseudo Neighboring gene PDI-like 5-1 Neighboring gene cytochrome B561, amino-terminal protein Neighboring gene nuclear factor Y, subunit C10

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Interaction map of Arabidopsis Mediator complex expounding its topology. Maji S, et al. Nucleic Acids Res, 2019 May 7. PMID 30793213, Free PMC Article
    2. Purification of a plant mediator from Arabidopsis thaliana identifies PFT1 as the Med25 subunit. Bäckström S, et al. Mol Cell, 2007 Jun 8. PMID 17560376
    3. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    NM_100669.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables transcription coregulator activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of mediator complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of mediator complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    Surfeit locus protein 5 subunit 22 of Mediator complex
    NP_563802.1
    • MED22B; FUNCTIONS IN: RNA polymerase II transcription mediator activity; INVOLVED IN: regulation of transcription from RNA polymerase II promoter; LOCATED IN: mediator complex; CONTAINS InterPro DOMAIN/s: Mediator complex, subunit Med22 (InterPro:IPR009332); BEST Arabidopsis thaliana protein match is: Surfeit locus protein 5 subunit 22 of Mediator complex (TAIR:AT1G16430.1); Has 245 Blast hits to 245 proteins in 83 species: Archae - 0; Bacteria - 0; Metazoa - 164; Fungi - 15; Plants - 53; Viruses - 0; Other Eukaryotes - 13 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      2465729..2467165 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001331744.1 → NP_001322426.1  Surfeit locus protein 5 subunit 22 of Mediator complex [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8ATZ6

    2. NM_100669.4 → NP_563802.1  Surfeit locus protein 5 subunit 22 of Mediator complex [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_563802.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8LCH5, Q9LN12
      UniProtKB/TrEMBL
      A0A178WMZ4, A0A5S9T7C9, A0A5S9URM1, A0A654EB59
      Conserved Domains (1) summary
      pfam06179
      Location:35 → 134
      Med22; Surfeit locus protein 5 subunit 22 of Mediator complex
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8LCH5.1

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