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    HIPP27 Heavy metal transport/detoxification superfamily protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 836743, updated on 18-Sep-2024

    Summary

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    Official Symbol
    HIPP27
    Official Full Name
    Heavy metal transport/detoxification superfamily protein
    Primary source
    TAIR:AT5G66110
    Locus tag
    AT5G66110
    See related
    Araport:AT5G66110
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    heavy metal associated isoprenylated plant protein 27; K2A18.19; K2A18_19
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    Genomic context

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    See HIPP27 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    2
    Sequence:
    Chromosome: 5; NC_003076.8 (26430071..26431351)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene Protein phosphatase 2C family protein Neighboring gene cell wall integrity/stress response component Neighboring gene winged-helix DNA-binding transcription factor family protein Neighboring gene 3-dehydroquinate synthase Neighboring gene RADIATION SENSITIVE 17 Neighboring gene proteasome alpha subunit D2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Functional analysis of a susceptibility gene (HIPP27) in the Arabidopsis thaliana-Meloidogyne incognita pathosystem by using a genome editing strategy. Dutta TK, et al. BMC Plant Biol, 2023 Aug 11. PMID 37563544, Free PMC Article
    2. UBIQUITIN-SPECIFIC PROTEASE16 interacts with a HEAVY METAL ASSOCIATED ISOPRENYLATED PLANT PROTEIN27 and modulates cadmium tolerance. Zhao J, et al. Plant Signal Behav, 2013 Oct. PMID 23857362, Free PMC Article
    3. Stress induced and nuclear localized HIPP26 from Arabidopsis thaliana interacts via its heavy metal associated domain with the drought stress related zinc finger transcription factor ATHB29. Barth O, et al. Plant Mol Biol, 2009 Jan. PMID 18974936
    4. A high content in lipid-modified peripheral proteins and integral receptor kinases features in the arabidopsis plasma membrane proteome. Marmagne A, et al. Mol Cell Proteomics, 2007 Nov. PMID 17644812
    5. Evidence for network evolution in an Arabidopsis interactome map. Arabidopsis Interactome Mapping Consortium. Science, 2011 Jul 29. PMID 21798944, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Functional analysis of a susceptibility gene (HIPP27) in the Arabidopsis thaliana-Meloidogyne incognita pathosystem by using a genome editing strategy.
      Title: Functional analysis of a susceptibility gene (HIPP27) in the Arabidopsis thaliana-Meloidogyne incognita pathosystem by using a genome editing strategy.
    2. UBIQUITIN-SPECIFIC PROTEASE16 interacts with a HEAVY METAL ASSOCIATED ISOPRENYLATED PLANT PROTEIN27 and modulates cadmium tolerance
      Title: UBIQUITIN-SPECIFIC PROTEASE16 interacts with a HEAVY METAL ASSOCIATED ISOPRENYLATED PLANT PROTEIN27 and modulates cadmium tolerance.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_001345747.1
    NM_126009.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in response to nematode IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  
    located_in plasma membrane HDA PubMed 

    General protein information

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    Preferred Names
    Heavy metal transport/detoxification superfamily protein
    NP_201412.2
    • Heavy metal transport/detoxification superfamily protein; FUNCTIONS IN: metal ion binding; INVOLVED IN: metal ion transport; LOCATED IN: plasma membrane; EXPRESSED IN: cultured cell, leaf; EXPRESSED DURING: LP.04 four leaves visible; CONTAINS InterPro DOMAIN/s: Heavy metal transport/detoxification protein (InterPro:IPR006121); BEST Arabidopsis thaliana protein match is: farnesylated protein 6 (TAIR:AT4G38580.1); Has 1185 Blast hits to 1108 proteins in 39 species: Archae - 2; Bacteria - 2; Metazoa - 2; Fungi - 3; Plants - 1176; Viruses - 0; Other Eukaryotes - 0 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      26430071..26431351
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001345746.1 → NP_001332182.1  Heavy metal transport/detoxification superfamily protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178UU72, A0A1P8BG72, A0A384KGN8
      Conserved Domains (1) summary
      cd00371
      Location:1 → 56
      HMA; Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain ...

    2. NM_126009.3 → NP_201412.2  Heavy metal transport/detoxification superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_201412.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q67ZW1, Q9FKX1
      Conserved Domains (1) summary
      cd00371
      Location:22 → 82
      HMA; Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain ...

    3. NM_001345747.1 → NP_001332183.1  Heavy metal transport/detoxification superfamily protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q67ZW1, Q9FKX1
      Conserved Domains (1) summary
      cd00371
      Location:22 → 82
      HMA; Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q67ZW1.1

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