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    nucleotide-sensitive chloride conductance regulator (ICln) family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 836350, updated on 18-Sep-2024

    Summary

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    Official Full Name
    nucleotide-sensitive chloride conductance regulator (ICln) family protein
    Primary source
    TAIR:AT5G62290
    Locus tag
    AT5G62290
    See related
    Araport:AT5G62290
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    MMI9.12; MMI9_12
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    Genomic context

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    Location:
    chromosome: 5
    Exon count:
    7
    Sequence:
    Chromosome: 5; NC_003076.8 (25019175..25021131)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene miscRNA Neighboring gene DUF1442 family protein (DUF1442) Neighboring gene Ribosomal protein S10p/S20e family protein Neighboring gene AGC (cAMP-dependent, cGMP-dependent and protein kinase C) kinase family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. PICLN modulates alternative splicing and light/temperature responses in plants. Mateos JL, et al. Plant Physiol, 2023 Feb 12. PMID 36423226, Free PMC Article
    2. Evidence for network evolution in an Arabidopsis interactome map. Arabidopsis Interactome Mapping Consortium. Science, 2011 Jul 29. PMID 21798944, Free PMC Article
    3. Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Tabata S, et al. Nature, 2000 Dec 14. PMID 11130714

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_001126006.1
    NM_125623.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in cell volume homeostasis IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in chloride transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in mRNA splicing, via spliceosome IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in spliceosomal snRNP assembly IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within spliceosomal snRNP assembly ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of methylosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of methylosome IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  
    part_of pICln-Sm protein complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    nucleotide-sensitive chloride conductance regulator (ICln) family protein
    NP_001119478.1
    • nucleotide-sensitive chloride conductance regulator (ICln) family protein; FUNCTIONS IN: ion channel activity; INVOLVED IN: cell volume homeostasis, chloride transport; LOCATED IN: cellular_component unknown; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Nucleotide-sensitive chloride conductance regulator (InterPro:IPR003521); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).
    NP_201035.1
    • nucleotide-sensitive chloride conductance regulator (ICln) family protein; FUNCTIONS IN: ion channel activity; INVOLVED IN: cell volume homeostasis, chloride transport; LOCATED IN: cellular_component unknown; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Nucleotide-sensitive chloride conductance regulator (InterPro:IPR003521); Has 295 Blast hits to 295 proteins in 110 species: Archae - 0; Bacteria - 0; Metazoa - 165; Fungi - 42; Plants - 66; Viruses - 0; Other Eukaryotes - 22 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      25019175..25021131
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_125623.3 → NP_201035.1  nucleotide-sensitive chloride conductance regulator (ICln) family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_201035.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      B3H4U0, Q9LVA7
      UniProtKB/TrEMBL
      A0A178UE38, A0A5S9YGI1, A0A7G2FPE4
      Conserved Domains (1) summary
      pfam03517
      Location:49 → 152
      Voldacs; Regulator of volume decrease after cellular swelling

    2. NM_001126006.1 → NP_001119478.1  nucleotide-sensitive chloride conductance regulator (ICln) family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001119478.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A7G2FPE4
      Conserved Domains (2) summary
      pfam03517
      Location:49 → 168
      Voldacs; Regulator of volume decrease after cellular swelling
      cl17171
      Location:16 → 68
      PH-like; Pleckstrin homology-like domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9LVA7.1

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