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    Nuclear transport factor 2 (NTF2) family protein with RNA binding (RRM-RBD-RNP motifs) domain-containing protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 836219, updated on 18-Sep-2024

    Summary

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    Official Full Name
    Nuclear transport factor 2 (NTF2) family protein with RNA binding (RRM-RBD-RNP motifs) domain-containing protein
    Primary source
    TAIR:AT5G60980
    Locus tag
    AT5G60980
    See related
    Araport:AT5G60980
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    MSL3.12; MSL3_12
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    Genomic context

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    Location:
    chromosome: 5
    Exon count:
    9
    Sequence:
    Chromosome: 5; NC_003076.8 (24543136..24546352)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene miscRNA Neighboring gene DEA(D/H)-box RNA helicase family protein Neighboring gene Replication factor-A protein 1-like protein Neighboring gene exocyst subunit exo70 family protein E2 Neighboring gene evolutionarily conserved C-terminal region 3

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Nuclear Localization of G3BP6 Is Essential for the Flowering Transition in Arabidopsis. Wang Y, et al. Biomolecules, 2023 Nov 24. PMID 38136569, Free PMC Article
    2. AtMBD6, a methyl CpG binding domain protein, maintains gene silencing in Arabidopsis by interacting with RNA binding proteins. Parida AP, et al. J Biosci, 2017 Mar. PMID 28229965
    3. Interactome of the plant-specific ESCRT-III component AtVPS2.2 in Arabidopsis thaliana. Ibl V, et al. J Proteome Res, 2012 Jan 1. PMID 22010978, Free PMC Article
    4. Interactome analysis reveals versatile functions of Arabidopsis COLD SHOCK DOMAIN PROTEIN 3 in RNA processing within the nucleus and cytoplasm. Kim MH, et al. Cell Stress Chaperones, 2013 Jul. PMID 23334891, Free PMC Article
    5. In Planta Determination of the mRNA-Binding Proteome of Arabidopsis Etiolated Seedlings. Reichel M, et al. Plant Cell, 2016 Oct. PMID 27729395, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_001345438.1
    NM_001345439.1
    NM_125491.3
    NM_180904.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables mRNA binding HDA PubMed 
    enables mRNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in stress granule assembly IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plastid HDA PubMed 

    General protein information

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    Preferred Names
    Nuclear transport factor 2 (NTF2) family protein with RNA binding (RRM-RBD-RNP motifs) domain-containing protein
    NP_200906.2
    • Nuclear transport factor 2 (NTF2) family protein with RNA binding (RRM-RBD-RNP motifs) domain; FUNCTIONS IN: RNA binding, nucleotide binding, nucleic acid binding; INVOLVED IN: transport, nucleocytoplasmic transport; LOCATED IN: intracellular; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Nuclear transport factor 2 (InterPro:IPR002075), RNA recognition motif, RNP-1 (InterPro:IPR000504), Nuclear transport factor 2, Eukaryote (InterPro:IPR018222), Nucleotide-binding, alpha-beta plait (InterPro:IPR012677); BEST Arabidopsis thaliana protein match is: Nuclear transport factor 2 (NTF2) family protein with RNA binding (RRM-RBD-RNP motifs) domain (TAIR:AT3G25150.1); Has 36196 Blast hits to 15965 proteins in 1132 species: Archae - 9; Bacteria - 13386; Metazoa - 10288; Fungi - 3119; Plants - 4760; Viruses - 542; Other Eukaryotes - 4092 (source: NCBI BLink).
    NP_851235.1
    • Nuclear transport factor 2 (NTF2) family protein with RNA binding (RRM-RBD-RNP motifs) domain; FUNCTIONS IN: RNA binding, nucleotide binding, nucleic acid binding; INVOLVED IN: transport, nucleocytoplasmic transport; LOCATED IN: intracellular; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Nuclear transport factor 2 (InterPro:IPR002075), Nuclear transport factor 2, Eukaryote (InterPro:IPR018222), RNA recognition motif, RNP-1 (InterPro:IPR000504), Nucleotide-binding, alpha-beta plait (InterPro:IPR012677); BEST Arabidopsis thaliana protein match is: Nuclear transport factor 2 (NTF2) family protein with RNA binding (RRM-RBD-RNP motifs) domain (TAIR:AT3G25150.1); Has 35964 Blast hits to 15476 proteins in 1126 species: Archae - 10; Bacteria - 13365; Metazoa - 10215; Fungi - 3021; Plants - 4733; Viruses - 543; Other Eukaryotes - 4077 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      24543136..24546352
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_125491.3 → NP_200906.2  Nuclear transport factor 2 (NTF2) family protein with RNA binding (RRM-RBD-RNP motifs) domain-containing protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_200906.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      F4K1Y4, Q8LEI7, Q9FME2
      UniProtKB/TrEMBL
      A0A178U8D7, A0A5S9YH33, A0A654GD21
      Conserved Domains (2) summary
      smart00360
      Location:294 → 365
      RRM; RNA recognition motif
      cd00780
      Location:12 → 131
      NTF2; Nuclear transport factor 2 (NTF2) domain plays an important role in the trafficking of macromolecules, ions and small molecules between the cytoplasm and nucleus. This bi-directional transport of macromolecules across the nuclear envelope requires many ...

    2. NM_001345438.1 → NP_001331368.1  Nuclear transport factor 2 (NTF2) family protein with RNA binding (RRM-RBD-RNP motifs) domain-containing protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      F4K1Y4, Q8LEI7, Q9FME2
      UniProtKB/TrEMBL
      A0A178U8D7, A0A5S9YH33, A0A654GD21
      Conserved Domains (2) summary
      smart00360
      Location:294 → 365
      RRM; RNA recognition motif
      cd00780
      Location:12 → 131
      NTF2; Nuclear transport factor 2 (NTF2) domain plays an important role in the trafficking of macromolecules, ions and small molecules between the cytoplasm and nucleus. This bi-directional transport of macromolecules across the nuclear envelope requires many ...

    3. NM_180904.2 → NP_851235.1  Nuclear transport factor 2 (NTF2) family protein with RNA binding (RRM-RBD-RNP motifs) domain-containing protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_851235.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178U9D2
      Conserved Domains (3) summary
      COG0724
      Location:283 → 352
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      cd00780
      Location:12 → 131
      NTF2; Nuclear transport factor 2 (NTF2) domain plays an important role in the trafficking of macromolecules, ions and small molecules between the cytoplasm and nucleus. This bi-directional transport of macromolecules across the nuclear envelope requires many ...
      cl17169
      Location:293 → 365
      RRM_SF; RNA recognition motif (RRM) superfamily

    4. NM_001345439.1 → NP_001331369.1  Nuclear transport factor 2 (NTF2) family protein with RNA binding (RRM-RBD-RNP motifs) domain-containing protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178U9D2
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9FME2.1

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