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    FIP1[V] FIP1[V]-like protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 835916, updated on 18-Sep-2024

    Summary

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    Official Symbol
    FIP1[V]
    Official Full Name
    FIP1[V]-like protein
    Primary source
    TAIR:AT5G58040
    Locus tag
    AT5G58040
    See related
    Araport:AT5G58040
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATFIP1[V]; ATFIPS5; FIPS5; homolog of yeast FIP1 [V]; K21L19.3; K21L19_3
    Summary
    Encodes a subunit of the polyadenylation apparatus that interacts with and stimulates the activity of poly(A) polymerase. Additionally, it interacts with several polyadenylation factor subunits and is an RNA-binding protein. It is suggested that this protein coordinates a number of polyadenylation factor subunits with PAP and with RNA.
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    Genomic context

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    See FIP1[V] in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    8
    Sequence:
    Chromosome: 5; NC_003076.8 (23488745..23494259)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene LJRHL1-like 3 Neighboring gene RTF2 RING-finger protein Neighboring gene Transport protein particle (TRAPP) component Neighboring gene SHV3-like 4 Neighboring gene SNARE-like superfamily protein Neighboring gene temperature-induced lipocalin Neighboring gene response regulator 18

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A novel endonuclease activity associated with the Arabidopsis ortholog of the 30-kDa subunit of cleavage and polyadenylation specificity factor. Addepalli B, et al. Nucleic Acids Res, 2007. PMID 17576667, Free PMC Article
    2. The interaction between two Arabidopsis polyadenylation factor subunits involves an evolutionarily-conserved motif and has implications for the assembly and function of the polyadenylation complex. Addepalli B, et al. Protein Pept Lett, 2008. PMID 18221017
    3. CONSTITUTIVE EXPRESSER OF PATHOGENESIS-RELATED GENES 5 is an RNA-binding protein controlling plant immunity via an RNA processing complex. Peng S, et al. Plant Cell, 2022 Apr 26. PMID 35137215, Free PMC Article
    4. An Arabidopsis Fip1 homolog interacts with RNA and provides conceptual links with a number of other polyadenylation factor subunits. Forbes KP, et al. J Biol Chem, 2006 Jan 6. PMID 16282318
    5. Arabidopsis mRNA polyadenylation machinery: comprehensive analysis of protein-protein interactions and gene expression profiling. Hunt AG, et al. BMC Genomics, 2008 May 14. PMID 18479511, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. polyadenylation factor subunit, CstF77 was identified as interacting with Fip1[V]; the domain of CstF77 that interacts with Fip1 [V] lies at its extreme C-terminus
      Title: The interaction between two Arabidopsis polyadenylation factor subunits involves an evolutionarily-conserved motif and has implications for the assembly and function of the polyadenylation complex.
    2. results indicate that the Arabidopsis Fip1, like its human counterpart, is an RNA-binding protein
      Title: An Arabidopsis Fip1 homolog interacts with RNA and provides conceptual links with a number of other polyadenylation factor subunits.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_125189.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables RNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables identical protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in RNA processing IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nuclear speck IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    FIP1[V]-like protein
    NP_200612.2
    • homolog of yeast FIP1 [V] (FIP1[V]); FUNCTIONS IN: protein binding, RNA binding; INVOLVED IN: biological_process unknown; LOCATED IN: cellular_component unknown; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Fip1 (InterPro:IPR007854); BEST Arabidopsis thaliana protein match is: fip1 motif-containing protein (TAIR:AT3G66652.2); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      23488745..23494259
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001345286.1 → NP_001332116.1  FIP1[V]-like protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8BFZ5, A0A5S9YFQ6, A0A7G2FHX8
      Conserved Domains (3) summary
      PRK12678
      Location:581 → 797
      PRK12678; transcription termination factor Rho; Provisional
      pfam05182
      Location:337 → 379
      Fip1; Fip1 motif
      NF033845
      Location:429 → 691
      MSCRAMM_ClfB; MSCRAMM family adhesin clumping factor ClfB

    2. NM_125189.3 → NP_200612.2  FIP1[V]-like protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_200612.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      F4KDH9, Q9FGU0
      UniProtKB/TrEMBL
      A0A5S9YFQ6
      Conserved Domains (1) summary
      pfam05182
      Location:337 → 379
      Fip1; Fip1 motif
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    F4KDH9.1

    Gene LinkOut

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