Transcriptional coactivator/pterin dehydratase [Arabidopsis thaliana (thale cress)] - Gene

Summary

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Official Full Name: Transcriptional coactivator/pterin dehydratase
Primary source: TAIR:AT5G51110
Locus tag: AT5G51110
See related: Araport:AT5G51110
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: MWD22.5; MWD22_5
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Genomic context

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See in Genome Data Viewer

Location:: chromosome: 5

Exon count:: 3

Sequence:: Chromosome: 5; NC_003076.8 (20777501..20779488, complement)

Chromosome 5 - NC_003076.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003076.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

RAF2 is probably involved in RuBisCO assembly. [RAF2]
Title: RAF2 is a RuBisCO assembly factor in Arabidopsis thaliana.

Submit: New GeneRIF Correction

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Homology

Orthologs from OrthoDB

NM_001203581.1

Supported by ESTs:

NM_124490.5

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables 4-alpha-hydroxytetrahydrobiopterin dehydratase activity	IEA Inferred from Electronic Annotation more info
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
acts_upstream_of_or_within response to abscisic acid	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within response to salt stress	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within ribulose bisphosphate carboxylase complex assembly	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in tetrahydrobiopterin biosynthetic process	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in cell periphery	IDA Inferred from Direct Assay more info	PubMed
located_in chloroplast	HDA more info	PubMed
located_in chloroplast	IDA Inferred from Direct Assay more info	PubMed
located_in chloroplast	ISM Inferred from Sequence Model more info
located_in chloroplast stroma	IDA Inferred from Direct Assay more info	PubMed
located_in nucleus	IDA Inferred from Direct Assay more info	PubMed
located_in plastid	HDA more info	PubMed

General protein information

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Preferred Names: Transcriptional coactivator/pterin dehydratase

NP_001190510.1

Transcriptional coactivator/pterin dehydratase; FUNCTIONS IN: 4-alpha-hydroxytetrahydrobiopterin dehydratase activity; INVOLVED IN: tetrahydrobiopterin biosynthetic process; EXPRESSED IN: 21 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Transcriptional coactivator/pterin dehydratase (InterPro:IPR001533); BEST Arabidopsis thaliana protein match is: Transcriptional coactivator/pterin dehydratase (TAIR:AT1G29810.1).

NP_199924.1

Transcriptional coactivator/pterin dehydratase; FUNCTIONS IN: 4-alpha-hydroxytetrahydrobiopterin dehydratase activity; INVOLVED IN: tetrahydrobiopterin biosynthetic process; LOCATED IN: chloroplast; EXPRESSED IN: 21 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Transcriptional coactivator/pterin dehydratase (InterPro:IPR001533); BEST Arabidopsis thaliana protein match is: Transcriptional coactivator/pterin dehydratase (TAIR:AT1G29810.1); Has 1849 Blast hits to 1849 proteins in 364 species: Archae - 43; Bacteria - 697; Metazoa - 0; Fungi - 2; Plants - 93; Viruses - 0; Other Eukaryotes - 1014 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003076.8 Reference assembly

Range

20777501..20779488 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_124490.5 → NP_199924.1 Transcriptional coactivator/pterin dehydratase [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_199924.1

Status: REVIEWED

UniProtKB/Swiss-Prot

Q8GZ70, Q8L944, Q9LU63

UniProtKB/TrEMBL

A0A178UCR6, A0A5S9YD32

Conserved Domains (1) summary

cd00913
Location:128 → 207

PCD_DCoH_subfamily_a; PCD_DCoH: The bifunctional protein pterin-4alpha-carbinolamine dehydratase (PCD), also known as DCoH (dimerization cofactor of hepatocyte nuclear factor-1), is both a transcription activator and a metabolic enzyme. DCoH stimulates gene expression by ...
NM_001203581.1 → NP_001190510.1 Transcriptional coactivator/pterin dehydratase [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_001190510.1

Status: REVIEWED

UniProtKB/TrEMBL

F4KBV0

Conserved Domains (1) summary

cd00913
Location:101 → 180

PCD_DCoH_subfamily_a; PCD_DCoH: The bifunctional protein pterin-4alpha-carbinolamine dehydratase (PCD), also known as DCoH (dimerization cofactor of hepatocyte nuclear factor-1), is both a transcription activator and a metabolic enzyme. DCoH stimulates gene expression by ...