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    ENHANCED DISEASE RESISTANCE protein (DUF1336) [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 833472, updated on 18-Sep-2024

    Summary

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    Official Full Name
    ENHANCED DISEASE RESISTANCE protein (DUF1336)
    Primary source
    TAIR:AT5G35180
    Locus tag
    AT5G35180
    See related
    Araport:AT5G35180
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    T25C13.60; T25C13_60
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    Genomic context

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    Location:
    chromosome: 5
    Exon count:
    26
    Sequence:
    Chromosome: 5; NC_003076.8 (13424316..13433067)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene Endomembrane protein 70 protein family Neighboring gene adenylate kinase family protein Neighboring gene proline-rich extensin-like family protein Neighboring gene Defensin-like (DEFL) family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Learning the lipid language of plant signalling. van Leeuwen W, et al. Trends Plant Sci, 2004 Aug. PMID 15358268
    2. Analysis of the Arabidopsis cytosolic proteome highlights subcellular partitioning of central plant metabolism. Ito J, et al. J Proteome Res, 2011 Apr 1. PMID 21166475
    3. Global Analysis of Membrane-associated Protein Oligomerization Using Protein Correlation Profiling. McBride Z, et al. Mol Cell Proteomics, 2017 Nov. PMID 28887381, Free PMC Article
    4. Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Tabata S, et al. Nature, 2000 Dec 14. PMID 11130714

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    NM_001125838.2
    NM_001125839.2
    NM_001161275.1
    NM_122909.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables lipid binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables phosphatidylinositol binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within signal transduction ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Component Evidence Code Pubs
    NOT located_in cytosol RCA
    inferred from Reviewed Computational Analysis
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  
    located_in plastid HDA PubMed 

    General protein information

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    Preferred Names
    ENHANCED DISEASE RESISTANCE protein (DUF1336)
    NP_001119310.1
    • FUNCTIONS IN: phosphoinositide binding; INVOLVED IN: signal transduction; LOCATED IN: plasma membrane; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Protein of unknown function DUF1336 (InterPro:IPR009769), Lipid-binding START (InterPro:IPR002913), Pleckstrin homology (InterPro:IPR001849); BEST Arabidopsis thaliana protein match is: ENHANCED DISEASE RESISTANCE 2 (TAIR:AT4G19040.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).
    NP_001119311.1
    • FUNCTIONS IN: phosphoinositide binding; INVOLVED IN: signal transduction; LOCATED IN: plasma membrane; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Lipid-binding START (InterPro:IPR002913), Pleckstrin homology (InterPro:IPR001849); BEST Arabidopsis thaliana protein match is: Pleckstrin homology (PH) domain-containing protein / lipid-binding START domain-containing protein (TAIR:AT5G45560.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).
    NP_001154747.1
    • FUNCTIONS IN: phosphoinositide binding; INVOLVED IN: signal transduction; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Protein of unknown function DUF1336 (InterPro:IPR009769), Lipid-binding START (InterPro:IPR002913); BEST Arabidopsis thaliana protein match is: ENHANCED DISEASE RESISTANCE 2 (TAIR:AT4G19040.1); Has 454 Blast hits to 426 proteins in 37 species: Archae - 0; Bacteria - 0; Metazoa - 1; Fungi - 2; Plants - 378; Viruses - 2; Other Eukaryotes - 71 (source: NCBI BLink).
    NP_568526.1
    • FUNCTIONS IN: phosphoinositide binding; INVOLVED IN: signal transduction; LOCATED IN: plasma membrane; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Protein of unknown function DUF1336 (InterPro:IPR009769), Lipid-binding START (InterPro:IPR002913), Pleckstrin homology (InterPro:IPR001849); BEST Arabidopsis thaliana protein match is: ENHANCED DISEASE RESISTANCE 2 (TAIR:AT4G19040.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      13424316..13433067
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001344098.1 → NP_001332513.1  ENHANCED DISEASE RESISTANCE protein (DUF1336) [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178UKI1, A0A1P8BH65

    2. NM_122909.3 → NP_568526.1  ENHANCED DISEASE RESISTANCE protein (DUF1336) [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_568526.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178UKI1, A0A5S9Y8L4, Q8W553
      Conserved Domains (1) summary
      PLN00188
      Location:60 → 774
      PLN00188; enhanced disease resistance protein (EDR2); Provisional

    3. NM_001125838.2 → NP_001119310.1  ENHANCED DISEASE RESISTANCE protein (DUF1336) [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001119310.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178UL44, B3H5W6
      Conserved Domains (3) summary
      cd00177
      Location:238 → 437
      START; Lipid-binding START domain of mammalian STARD1-STARD15 and related proteins
      PLN00188
      Location:60 → 774
      PLN00188; enhanced disease resistance protein (EDR2); Provisional
      pfam07059
      Location:563 → 768
      DUF1336; Protein of unknown function (DUF1336)

    4. NM_001161275.1 → NP_001154747.1  ENHANCED DISEASE RESISTANCE protein (DUF1336) [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001154747.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178UKI1, F4JYC1
      Conserved Domains (3) summary
      cd00177
      Location:238 → 470
      START; Lipid-binding START domain of mammalian STARD1-STARD15 and related proteins
      PLN00188
      Location:60 → 807
      PLN00188; enhanced disease resistance protein (EDR2); Provisional
      pfam07059
      Location:596 → 801
      DUF1336; Protein of unknown function (DUF1336)

    5. NM_001125839.2 → NP_001119311.1  ENHANCED DISEASE RESISTANCE protein (DUF1336) [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001119311.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      B3H745
      Conserved Domains (3) summary
      cd00177
      Location:238 → 437
      START; Lipid-binding START domain of mammalian STARD1-STARD15 and related proteins
      PLN00188
      Location:60 → 585
      PLN00188; enhanced disease resistance protein (EDR2); Provisional
      pfam07059
      Location:563 → 586
      DUF1336; Protein of unknown function (DUF1336)
    Nucleotide Protein
    Heading Accession and Version

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