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    U-box domain-containing protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 831392, updated on 18-Sep-2024

    Summary

    Official Full Name
    U-box domain-containing protein
    Primary source
    TAIR:AT5G15400
    Locus tag
    AT5G15400
    See related
    Araport:AT5G15400
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    MUSE3; Mutant; snc1 -enhancing 3; T20K14.10; T20K14_10
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    Genomic context

    Location:
    chromosome: 5
    Exon count:
    16
    Sequence:
    Chromosome: 5; NC_003076.8 (4997489..5003253, complement)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene domains rearranged methylase 1 Neighboring gene tRNA/rRNA methyltransferase (SpoU) family protein Neighboring gene Cyclic nucleotide-regulated ion channel family protein Neighboring gene uncharacterized protein Neighboring gene Plant calmodulin-binding protein-like protein

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    NM_121544.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables ubiquitin protein ligase activity IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    enables ubiquitin-ubiquitin ligase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in ERAD pathway IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within negative regulation of defense response IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    involved_in protein ubiquitination IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within protein ubiquitination IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    acts_upstream_of_or_within ubiquitin-dependent protein catabolic process IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
     
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    part_of ubiquitin ligase complex IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    U-box domain-containing protein
    NP_568313.2
    • U-box domain-containing protein; FUNCTIONS IN: ubiquitin-protein ligase activity, ubiquitin-ubiquitin ligase activity; INVOLVED IN: protein ubiquitination, ubiquitin-dependent protein catabolic process; LOCATED IN: ubiquitin ligase complex; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Ubiquitin conjugation factor E4, core (InterPro:IPR019474), U box domain (InterPro:IPR003613); Has 1036 Blast hits to 1011 proteins in 209 species: Archae - 0; Bacteria - 0; Metazoa - 503; Fungi - 218; Plants - 177; Viruses - 0; Other Eukaryotes - 138 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      4997489..5003253 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_121544.4NP_568313.2  U-box domain-containing protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_568313.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9LF41
      UniProtKB/TrEMBL
      A0A5S9Y6I6, A0A654G1E5
      Conserved Domains (2) summary
      cd16657
      Location:9431012
      RING-Ubox_UBE4A; U-box domain, a modified RING finger, found in ubiquitin conjugation factor E4 A (UBE4A) and similar proteins
      pfam10408
      Location:265924
      Ufd2P_core; Ubiquitin elongating factor core