KEA6 K+ efflux antiporter 6 [Arabidopsis thaliana (thale cress)] - Gene

Summary

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Official Symbol: KEA6
Official Full Name: K+ efflux antiporter 6
Primary source: TAIR:AT5G11800
Locus tag: AT5G11800
See related: Araport:AT5G11800
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: ARABIDOPSIS THALIANA K+ EFFLUX ANTIPORTER 6; ATKEA6; K+ efflux antiporter 6; T22P22.190; T22P22_190
Summary: member of Putative potassium proton antiporter family
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Genomic context

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See KEA6 in Genome Data Viewer

Location:: chromosome: 5

Exon count:: 20

Sequence:: Chromosome: 5; NC_003076.8 (3803315..3808273, complement)

Chromosome 5 - NC_003076.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003076.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Golgi-localized and regulates ionic homeostasis and skotomorphogenesis
Title: Golgi-localized cation/proton exchangers regulate ionic homeostasis and skotomorphogenesis in Arabidopsis.
KEA6 is important for growth.KEA6 is endosomal K(+) transporter functioning in maintaining pH and ion homeostasis in the endomembrane network.
Title: K(+) Efflux Antiporters 4, 5, and 6 Mediate pH and K(+) Homeostasis in Endomembrane Compartments.

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Homology

Orthologs from OrthoDB

NM_121218.5

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables potassium ion transmembrane transporter activity	ISS Inferred from Sequence or Structural Similarity more info
enables potassium:proton antiporter activity	IEA Inferred from Electronic Annotation more info
enables potassium:proton antiporter activity	NAS Non-traceable Author Statement more info	PubMed

Process	Evidence Code	Pubs
involved_in potassium ion transmembrane transport	IEA Inferred from Electronic Annotation more info
involved_in proton transmembrane transport	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in cellular_component	ND No biological Data available more info

General protein information

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Preferred Names: K+ efflux antiporter 6

NP_196741.2

K+ efflux antiporter 6 (KEA6); FUNCTIONS IN: potassium:hydrogen antiporter activity, potassium ion transmembrane transporter activity; INVOLVED IN: potassium ion transport, cation transport, transmembrane transport; LOCATED IN: membrane; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Cation/H+ exchanger (InterPro:IPR006153); BEST Arabidopsis thaliana protein match is: K+ efflux antiporter 4 (TAIR:AT2G19600.1); Has 10410 Blast hits to 10399 proteins in 2159 species: Archae - 365; Bacteria - 8460; Metazoa - 71; Fungi - 71; Plants - 421; Viruses - 0; Other Eukaryotes - 1022 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003076.8 Reference assembly

Range

3803315..3808273 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_121218.5 → NP_196741.2 K+ efflux antiporter 6 [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_196741.2

Status: REVIEWED

UniProtKB/Swiss-Prot

B5X0N6, Q9LYF1

UniProtKB/TrEMBL

A0A178UL54, A0A5S9Y3E8

Conserved Domains (1) summary

pfam00999
Location:181 → 553

Na_H_Exchanger; Sodium/hydrogen exchanger family