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    SLP2 subtilisin-like serine protease 2 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 829650, updated on 18-Sep-2024

    Summary

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    Official Symbol
    SLP2
    Official Full Name
    subtilisin-like serine protease 2
    Primary source
    TAIR:AT4G34980
    Locus tag
    AT4G34980
    See related
    Araport:AT4G34980
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    M4E13.40; M4E13_40; subtilisin-like serine protease 2
    Summary
    Serine protease similar to subtilisin.
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    Genomic context

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    See SLP2 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    1
    Sequence:
    Chromosome: 4; NC_003075.7 (16656622..16659486, complement)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene actin depolymerizing factor 9 Neighboring gene tRNA-Thr Neighboring gene myb domain protein 32 Neighboring gene ascorbate peroxidase 3

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003075.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Activation of Mitochondrial Protein Phosphatase SLP2 by MIA40 Regulates Seed Germination. Uhrig RG, et al. Plant Physiol, 2017 Feb. PMID 27923987, Free PMC Article
    2. Expression of subtilisin-like serine proteases in Arabidopsis thaliana is cell-specific and responds to jasmonic acid and heavy metals with developmental differences. Golldack D, et al. Physiol Plant, 2003 May. PMID 12702015
    3. Global Analysis of Membrane-associated Protein Oligomerization Using Protein Correlation Profiling. McBride Z, et al. Mol Cell Proteomics, 2017 Nov. PMID 28887381, Free PMC Article
    4. Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana. Mayer K, et al. Nature, 1999 Dec 16. PMID 10617198

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    NM_119664.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables serine-type endopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables serine-type peptidase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within plant-type cell wall modification TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular region ISM
    Inferred from Sequence Model
    more info
    		  
    located_in plasma membrane HDA PubMed 

    General protein information

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    Preferred Names
    subtilisin-like serine protease 2
    NP_567972.1
    • subtilisin-like serine protease 2 (SLP2); FUNCTIONS IN: serine-type peptidase activity; INVOLVED IN: plant-type cell wall modification, proteolysis; LOCATED IN: middle lamella-containing extracellular matrix, membrane; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Protease-associated PA (InterPro:IPR003137), Proteinase inhibitor, propeptide (InterPro:IPR009020), Peptidase S8/S53, subtilisin/kexin/sedolisin (InterPro:IPR000209), Peptidase S8, subtilisin-related (InterPro:IPR015500), Peptidase S8/S53, subtilisin, active site (InterPro:IPR022398), Proteinase inhibitor I9, subtilisin propeptide (InterPro:IPR010259); BEST Arabidopsis thaliana protein match is: Subtilase family protein (TAIR:AT3G14240.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      16656622..16659486 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_119664.3 → NP_567972.1  subtilisin-like serine protease 2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_567972.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O49607
      UniProtKB/TrEMBL
      A0A178V235, A0A5S9XYQ4
      Conserved Domains (5) summary
      cd04852
      Location:97 → 570
      Peptidases_S8_3; Peptidase S8 family domain, uncharacterized subfamily 3
      cd02120
      Location:343 → 467
      PA_subtilisin_like; Protease-associated domain containing subtilisin-like proteases. This group contains various PA domain-containing subtilisin-like proteases including melon cucumisin, Arabidopsis thaliana Ara12, a nodule specific serine protease from Alnus glutinosa ag12, ...
      pfam05922
      Location:33 → 99
      Inhibitor_I9; Peptidase inhibitor I9
      pfam17766
      Location:653 → 758
      fn3_6; Fibronectin type-III domain
      NF033865
      Location:536 → 615
      fusolisin; autotransporter serine protease fusolisin
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O49607.1

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