PRF4 profilin 4 [Arabidopsis thaliana (thale cress)] - Gene

Summary

Official Symbol: PRF4
Official Full Name: profilin 4
Primary source: TAIR:AT4G29340
Locus tag: AT4G29340
See related: Araport:AT4G29340
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: F17A13.160; F17A13_160; profilin 4
Summary: Profilin is a low-molecular weight, actin monomer-binding protein that regulates the organization of actin cytoskeleton in eukaryotes, including higher plants. PRF4 and PRF5 are late pollen-specific and are not detectable in other cell types of the plant body including microspores and root hairs. Immunocytochemical studies at the subcellular level reveal that both the constitutive and pollen-specific profilins are abundant in the cytoplasm. In vegetative cell types, such as root apical cells, profilins showed localization to nuclei in addition to the cytoplasmic staining.
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Chromosome 4 - NC_003075.7 Genomic Context describing neighboring genes

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Profilin promotes formin-mediated actin filament assembly and vesicle transport during polarity formation in pollen.
Title: Profilin promotes formin-mediated actin filament assembly and vesicle transport during polarity formation in pollen.
PRF4 and PRF5 regulate actin polymerization in pollen grains and tubes.
Title: Profilin Regulates Apical Actin Polymerization to Control Polarized Pollen Tube Growth.

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NM_119079.4

Component	Evidence Code	Pubs
located_in cytoplasm	IDA Inferred from Direct Assay more info	PubMed
located_in cytoplasm	ISM Inferred from Sequence Model more info
located_in nucleus	HDA more info	PubMed

NP_194663.1

profilin 4 (PRF4); FUNCTIONS IN: actin binding; INVOLVED IN: cytoskeleton organization, actin cytoskeleton organization; LOCATED IN: nucleus, actin cytoskeleton, cytoplasm; EXPRESSED IN: 11 plant structures; EXPRESSED DURING: L mature pollen stage, M germinated pollen stage, 4 anthesis, petal differentiation and expansion stage; CONTAINS InterPro DOMAIN/s: Profilin/allergen (InterPro:IPR002097), Profilin, plant (InterPro:IPR005455); BEST Arabidopsis thaliana protein match is: profilin 5 (TAIR:AT2G19770.1); Has 899 Blast hits to 898 proteins in 239 species: Archae - 0; Bacteria - 2; Metazoa - 128; Fungi - 117; Plants - 583; Viruses - 0; Other Eukaryotes - 69 (source: NCBI BLink).