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    CHLM magnesium-protoporphyrin IX methyltransferase [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 828611, updated on 18-Sep-2024

    Summary

    Official Symbol
    CHLM
    Official Full Name
    magnesium-protoporphyrin IX methyltransferase
    Primary source
    TAIR:AT4G25080
    Locus tag
    AT4G25080
    See related
    Araport:AT4G25080
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F24A6.6; magnesium-protoporphyrin IX methyltransferase; MGPIXMT
    Summary
    Encodes a protein with methyltransferase activity responsible for the methylation of magnesium protoporphyrin IX. Mutants defective in this gene are affected in chlorophyll biosynthesis and show a reduction in the accumulation of a number of major thylakoid-associated proteins including components of PSI (LHCI), PSII (LHCII, D1, CP43) and the cytochrome b6f complex (Cytf). By contrast, no significant changes were detected for the proteins of the stroma and the chloroplast envelope.
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    Genomic context

    See CHLM in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    3
    Sequence:
    Chromosome: 4; NC_003075.7 (12876822..12878703)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene acyl carrier protein 4 Neighboring gene caldesmon-like protein Neighboring gene Riboflavin synthase-like superfamily protein Neighboring gene Fe superoxide dismutase 1 Neighboring gene metacaspase 2

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Pathways from PubChem

    Interactions

    General gene information

    NM_001125580.1
    NM_001203903.1
    NM_118640.3
    NM_179107.2
    NM_179108.3

    Gene Ontology Provided by TAIR

    General protein information

    Preferred Names
    magnesium-protoporphyrin IX methyltransferase
    NP_001119052.1
    • magnesium-protoporphyrin IX methyltransferase (CHLM); FUNCTIONS IN: magnesium protoporphyrin IX methyltransferase activity; INVOLVED IN: chlorophyll biosynthetic process; LOCATED IN: chloroplast thylakoid membrane, chloroplast, chloroplast envelope; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Magnesium protoporphyrin O-methyltransferase (InterPro:IPR010251), Magnesium-protoporphyrin IX methyltransferase, C-terminal (InterPro:IPR010940); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).
    NP_001190832.1
    • magnesium-protoporphyrin IX methyltransferase (CHLM); CONTAINS InterPro DOMAIN/s: Magnesium-protoporphyrin IX methyltransferase, C-terminal (InterPro:IPR010940), Magnesium protoporphyrin O-methyltransferase (InterPro:IPR010251).
    NP_194238.1
    • magnesium-protoporphyrin IX methyltransferase (CHLM); FUNCTIONS IN: magnesium protoporphyrin IX methyltransferase activity; INVOLVED IN: chlorophyll biosynthetic process; LOCATED IN: chloroplast thylakoid membrane, chloroplast, chloroplast envelope; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Magnesium-protoporphyrin IX methyltransferase, C-terminal (InterPro:IPR010940), Magnesium protoporphyrin O-methyltransferase (InterPro:IPR010251); Has 3281 Blast hits to 3281 proteins in 1119 species: Archae - 36; Bacteria - 2263; Metazoa - 32; Fungi - 20; Plants - 76; Viruses - 0; Other Eukaryotes - 854 (source: NCBI BLink).
    NP_849438.1
    • magnesium-protoporphyrin IX methyltransferase (CHLM); FUNCTIONS IN: magnesium protoporphyrin IX methyltransferase activity; INVOLVED IN: chlorophyll biosynthetic process; LOCATED IN: chloroplast thylakoid membrane, chloroplast, chloroplast envelope; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Magnesium-protoporphyrin IX methyltransferase, C-terminal (InterPro:IPR010940), Magnesium protoporphyrin O-methyltransferase (InterPro:IPR010251); Has 3281 Blast hits to 3281 proteins in 1119 species: Archae - 36; Bacteria - 2263; Metazoa - 32; Fungi - 20; Plants - 76; Viruses - 0; Other Eukaryotes - 854 (source: NCBI BLink).
    NP_849439.1
    • magnesium-protoporphyrin IX methyltransferase (CHLM); FUNCTIONS IN: magnesium protoporphyrin IX methyltransferase activity; INVOLVED IN: chlorophyll biosynthetic process; LOCATED IN: chloroplast thylakoid membrane, chloroplast, chloroplast envelope; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Magnesium-protoporphyrin IX methyltransferase, C-terminal (InterPro:IPR010940), Magnesium protoporphyrin O-methyltransferase (InterPro:IPR010251); Has 3281 Blast hits to 3281 proteins in 1119 species: Archae - 36; Bacteria - 2263; Metazoa - 32; Fungi - 20; Plants - 76; Viruses - 0; Other Eukaryotes - 854 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      12876822..12878703
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001341721.1 → NP_001328344.1  magnesium-protoporphyrin IX methyltransferase [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8B4G1
    2. NM_001203903.1 → NP_001190832.1  magnesium-protoporphyrin IX methyltransferase [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001190832.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      B3H4K6, B9DF98, Q9SW18
      UniProtKB/TrEMBL
      A0A178V3C5, A0A5S9XVR1
      Conserved Domains (1) summary
      PLN02585
      Location:1 → 312
      PLN02585; magnesium protoporphyrin IX methyltransferase
    3. NM_179108.3 → NP_849439.1  magnesium-protoporphyrin IX methyltransferase [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_849439.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      B3H4K6, B9DF98, Q9SW18
      UniProtKB/TrEMBL
      A0A178V3C5, A0A5S9XVR1
      Conserved Domains (1) summary
      PLN02585
      Location:1 → 312
      PLN02585; magnesium protoporphyrin IX methyltransferase
    4. NM_118640.3 → NP_194238.1  magnesium-protoporphyrin IX methyltransferase [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_194238.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      B3H4K6, B9DF98, Q9SW18
      UniProtKB/TrEMBL
      A0A178V3C5, A0A5S9XVR1
      Conserved Domains (1) summary
      PLN02585
      Location:1 → 312
      PLN02585; magnesium protoporphyrin IX methyltransferase
    5. NM_179107.2 → NP_849438.1  magnesium-protoporphyrin IX methyltransferase [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_849438.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      B3H4K6, B9DF98, Q9SW18
      UniProtKB/TrEMBL
      A0A178V3C5, A0A5S9XVR1
      Conserved Domains (1) summary
      PLN02585
      Location:1 → 312
      PLN02585; magnesium protoporphyrin IX methyltransferase
    6. NM_001125580.1 → NP_001119052.1  magnesium-protoporphyrin IX methyltransferase [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001119052.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9SW18
      Conserved Domains (2) summary
      PRK07580
      Location:22 → 244
      PRK07580; Mg-protoporphyrin IX methyl transferase; Validated
      TIGR02021
      Location:22 → 242
      BchM-ChlM; magnesium protoporphyrin O-methyltransferase
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