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    CNX7 co-factor for nitrate, reductase and xanthine dehydrogenase 7 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 826601, updated on 18-Sep-2024

    Summary

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    Official Symbol
    CNX7
    Official Full Name
    co-factor for nitrate, reductase and xanthine dehydrogenase 7
    Primary source
    TAIR:AT4G10100
    Locus tag
    AT4G10100
    See related
    Araport:AT4G10100
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ''co-factor for nitrate; co-factor for nitrate; F28M11.20; F28M11_20; MOLYBDOPTERIN SYNTHASE; reductase and xanthine dehydrogenase 7; reductase and xanthine dehydrogenase 7''; SIR5
    Summary
    molybdenum cofactor synthesis family protein, similar to Molybdenum cofactor synthesis protein 2 small subunit (Molybdopterin- synthase small subunit) (MOCS2A) (MOCO1-A) (Swiss-Prot:O96033) (Homo sapiens); contains TIGRFAM TIGR01682: molybdopterin converting factor, subunit 1; sir loss-of-function mutants are resistant to sirtinol, a modulator of auxin signaling.
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    Genomic context

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    See CNX7 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    2
    Sequence:
    Chromosome: 4; NC_003075.7 (6308683..6309546)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene elongator protein 6 Neighboring gene ncRNA Neighboring gene RNA-binding (RRM/RBD/RNP motifs) family protein Neighboring gene SCR-like 20 Neighboring gene Sucrose-phosphate synthase family protein Neighboring gene DNAJ heat shock N-terminal domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003075.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. New GATEWAY vectors for high throughput analyses of protein-protein interactions by bimolecular fluorescence complementation. Gehl C, et al. Mol Plant, 2009 Sep. PMID 19825679
    2. ABA3 is a molybdenum cofactor sulfurase required for activation of aldehyde oxidase and xanthine dehydrogenase in Arabidopsis thaliana. Bittner F, et al. J Biol Chem, 2001 Nov 2. PMID 11553608
    3. Genetic and chemical analyses of the action mechanisms of sirtinol in Arabidopsis. Dai X, et al. Proc Natl Acad Sci U S A, 2005 Feb 22. PMID 15710899, Free PMC Article
    4. Quantitative analysis of dynamic protein-protein interactions in planta by a floated-leaf luciferase complementation imaging (FLuCI) assay using binary Gateway vectors. Gehl C, et al. Plant J, 2011 Aug. PMID 21481030
    5. Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana. Mayer K, et al. Nature, 1999 Dec 16. PMID 10617198

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_001084897.1
    NM_117078.4
    NM_179023.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within auxin-activated signaling pathway IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within molybdenum incorporation into molybdenum-molybdopterin complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    co-factor for nitrate, reductase and xanthine dehydrogenase 7
    NP_001078366.1
    • ''co-factor for nitrate, reductase and xanthine dehydrogenase 7'' (CNX7); CONTAINS InterPro DOMAIN/s: ThiamineS (InterPro:IPR003749), Molybdopterin converting factor, subunit 1 (InterPro:IPR010034), Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp (InterPro:IPR016155), Beta-grasp fold, ferredoxin-type (InterPro:IPR012675); Has 1000 Blast hits to 1000 proteins in 381 species: Archae - 21; Bacteria - 814; Metazoa - 52; Fungi - 2; Plants - 54; Viruses - 0; Other Eukaryotes - 57 (source: NCBI BLink).
    NP_567352.1
    • ''co-factor for nitrate, reductase and xanthine dehydrogenase 7'' (CNX7); CONTAINS InterPro DOMAIN/s: ThiamineS (InterPro:IPR003749), Molybdopterin converting factor, subunit 1 (InterPro:IPR010034), Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp (InterPro:IPR016155), Beta-grasp fold, ferredoxin-type (InterPro:IPR012675); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).
    NP_849354.1
    • ''co-factor for nitrate, reductase and xanthine dehydrogenase 7'' (CNX7); CONTAINS InterPro DOMAIN/s: ThiamineS (InterPro:IPR003749), Molybdopterin converting factor, subunit 1 (InterPro:IPR010034), Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp (InterPro:IPR016155), Beta-grasp fold, ferredoxin-type (InterPro:IPR012675); Has 1000 Blast hits to 1000 proteins in 381 species: Archae - 21; Bacteria - 814; Metazoa - 52; Fungi - 2; Plants - 54; Viruses - 0; Other Eukaryotes - 57 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      6308683..6309546
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_117078.4 → NP_567352.1  co-factor for nitrate, reductase and xanthine dehydrogenase 7 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_567352.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9S7A3
      UniProtKB/TrEMBL
      A0A178USP7, A0A5S9XRQ2
      Conserved Domains (1) summary
      PLN02799
      Location:15 → 96
      PLN02799; Molybdopterin synthase sulfur carrier subunit

    2. NM_001084897.1 → NP_001078366.1  co-factor for nitrate, reductase and xanthine dehydrogenase 7 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001078366.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9S7A3
      UniProtKB/TrEMBL
      A0A178USP7, A0A5S9XRQ2
      Conserved Domains (1) summary
      PLN02799
      Location:15 → 96
      PLN02799; Molybdopterin synthase sulfur carrier subunit

    3. NM_179023.2 → NP_849354.1  co-factor for nitrate, reductase and xanthine dehydrogenase 7 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_849354.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9S7A3
      UniProtKB/TrEMBL
      A0A178USP7, A0A5S9XRQ2
      Conserved Domains (1) summary
      PLN02799
      Location:15 → 96
      PLN02799; Molybdopterin synthase sulfur carrier subunit
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9S7A3.1

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