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    XT1 xylosyltransferase 1 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 825446, updated on 18-Sep-2024

    Summary

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    Official Symbol
    XT1
    Official Full Name
    xylosyltransferase 1
    Primary source
    TAIR:AT3G62720
    Locus tag
    AT3G62720
    See related
    Araport:AT3G62720
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATXT1; AtXXT1; XXT1; XYG XYLOSYLTRANSFERASE 1; xylosyltransferase 1
    Summary
    Encodes a protein with xylosyltransferase activity, which is specific for UDP-xylose as donor substrate and for oligosaccharides with a degree of polymerization >4. Although the enzyme utilizes either cellopentaose or cellohexaose, its activity is four-fold higher with cellohexaose as an acceptor compared to cellopentaose. The enzyme is able to add several xylosyl residues to the acceptor forming mono-, di- and trixylosylated polysaccharides.
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    Genomic context

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    See XT1 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    2
    Sequence:
    Chromosome: 3; NC_003074.8 (23201032..23202988)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene multidrug resistance-associated protein 10 Neighboring gene Glycosyl hydrolase family protein Neighboring gene pseudo Neighboring gene desiccation-like protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Lack of xyloglucan in the cell walls of the Arabidopsis xxt1/xxt2 mutant results in specific increases in homogalacturonan and glucomannan. Sowinski EE, et al. Plant J, 2022 Apr. PMID 35041247
    2. Disrupting two Arabidopsis thaliana xylosyltransferase genes results in plants deficient in xyloglucan, a major primary cell wall component. Cavalier DM, et al. Plant Cell, 2008 Jun. PMID 18544630, Free PMC Article
    3. Two xyloglucan xylosyltransferases catalyze the addition of multiple xylosyl residues to cellohexaose. Cavalier DM, et al. J Biol Chem, 2006 Nov 10. PMID 16982611
    4. Mutations in multiple XXT genes of Arabidopsis reveal the complexity of xyloglucan biosynthesis. Zabotina OA, et al. Plant Physiol, 2012 Aug. PMID 22696020, Free PMC Article
    5. Arabidopsis GT34 family contains five xyloglucan α-1,6-xylosyltransferases. Vuttipongchaikij S, et al. New Phytol, 2012 Aug. PMID 22670626

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Lack of xyloglucan in the cell walls of the Arabidopsis xxt1/xxt2 mutant results in specific increases in homogalacturonan and glucomannan.
      Title: Lack of xyloglucan in the cell walls of the Arabidopsis xxt1/xxt2 mutant results in specific increases in homogalacturonan and glucomannan.
    2. The supramolecular organization of the CSLC4, XXT1, XXT2, and XXT5 proteins in Arabidopsis protoplasts, was investigated.
      Title: Xyloglucan xylosyltransferases XXT1, XXT2, and XXT5 and the glucan synthase CSLC4 form Golgi-localized multiprotein complexes.
    3. XXT1 and XXT2 are responsible for the bulk of the xylosylation of the glucan backbone, and at least one of these proteins must be present and active for xyloglucan to be made. XXT5 plays a significant but as yet uncharacterized role in this process.
      Title: Mutations in multiple XXT genes of Arabidopsis reveal the complexity of xyloglucan biosynthesis.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_001035840.2
    NM_116137.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables UDP-xylosyltransferase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables glycosyltransferase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables xyloglucan 6-xylosyltransferase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within polysaccharide biosynthetic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in protein glycosylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within root hair elongation IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within xyloglucan biosynthetic process IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within xyloglucan metabolic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in Golgi apparatus HDA PubMed 
    located_in Golgi apparatus ISM
    Inferred from Sequence Model
    more info
    		  
    located_in Golgi medial cisterna HDA PubMed 
    located_in Golgi medial cisterna IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytosol HDA PubMed 
    located_in endosome HDA PubMed 
    located_in trans-Golgi network HDA PubMed 

    General protein information

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    Preferred Names
    xylosyltransferase 1
    NP_001030917.1
    • xylosyltransferase 1 (XT1); FUNCTIONS IN: xyloglucan 6-xylosyltransferase activity, UDP-xylosyltransferase activity, transferase activity, transferring glycosyl groups, transferase activity; INVOLVED IN: polysaccharide biosynthetic process, xyloglucan biosynthetic process, root hair elongation; LOCATED IN: mitochondrion, integral to membrane; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Galactosyl transferase (InterPro:IPR008630); BEST Arabidopsis thaliana protein match is: UDP-xylosyltransferase 2 (TAIR:AT4G02500.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).
    NP_191831.1
    • xylosyltransferase 1 (XT1); FUNCTIONS IN: xyloglucan 6-xylosyltransferase activity, UDP-xylosyltransferase activity, transferase activity, transferring glycosyl groups, transferase activity; INVOLVED IN: polysaccharide biosynthetic process, xyloglucan biosynthetic process, root hair elongation; LOCATED IN: mitochondrion, integral to membrane; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Galactosyl transferase (InterPro:IPR008630); BEST Arabidopsis thaliana protein match is: UDP-xylosyltransferase 2 (TAIR:AT4G02500.1); Has 441 Blast hits to 440 proteins in 92 species: Archae - 0; Bacteria - 4; Metazoa - 0; Fungi - 134; Plants - 286; Viruses - 0; Other Eukaryotes - 17 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      23201032..23202988
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001035840.2 → NP_001030917.1  xylosyltransferase 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001030917.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      B9DHH6, Q9LZJ3
      UniProtKB/TrEMBL
      A0A178VEJ0, A0A5S9XN48
      Conserved Domains (1) summary
      PLN03182
      Location:1 → 451
      PLN03182; xyloglucan 6-xylosyltransferase; Provisional

    2. NM_116137.3 → NP_191831.1  xylosyltransferase 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_191831.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      B9DHH6, Q9LZJ3
      UniProtKB/TrEMBL
      A0A178VEJ0, A0A5S9XN48
      Conserved Domains (1) summary
      PLN03182
      Location:1 → 451
      PLN03182; xyloglucan 6-xylosyltransferase; Provisional
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9LZJ3.1

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