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    RAB8 RAB GTPase homolog 8 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 824529, updated on 18-Sep-2024

    Summary

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    Official Symbol
    RAB8
    Official Full Name
    RAB GTPase homolog 8
    Primary source
    TAIR:AT3G53610
    Locus tag
    AT3G53610
    See related
    Araport:AT3G53610
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATRAB8; AtRab8B; AtRABE1a; GTPASE ATRAB8; RAB GTPase homolog 8
    Summary
    GTPase AtRAB8 (atrab8)
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    Genomic context

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    See RAB8 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    9
    Sequence:
    Chromosome: 3; NC_003074.8 (19876232..19878792, complement)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene miscRNA Neighboring gene ncRNA Neighboring gene C2H2-type zinc finger family protein Neighboring gene uncharacterized protein Neighboring gene pyrophosphorylase 4 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Plant proteins that interact with VirB2, the Agrobacterium tumefaciens pilin protein, mediate plant transformation. Hwang HH, et al. Plant Cell, 2004 Nov. PMID 15494553, Free PMC Article
    2. Arabidopsis Rab-E GTPases exhibit a novel interaction with a plasma-membrane phosphatidylinositol-4-phosphate 5-kinase. Camacho L, et al. J Cell Sci, 2009 Dec 1. PMID 19903693
    3. CHARACTERIZATION OF A RABE (RAS GENE FROM RAT BRAIN E) GTPASE EXPRESSED DURING MORPHOGENESIS IN THE UNICELLULAR GREEN ALGA MICRASTERIAS DENTICULATA (ZYGNEMATOPHYCEAE, STREPTOPHYTA)(1). Vannerum K, et al. J Phycol, 2012 Jun. PMID 27011085
    4. Identification of new intrinsic proteins in Arabidopsis plasma membrane proteome. Marmagne A, et al. Mol Cell Proteomics, 2004 Jul. PMID 15060130
    5. Evidence for network evolution in an Arabidopsis interactome map. Arabidopsis Interactome Mapping Consortium. Science, 2011 Jul 29. PMID 21798944, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_001084809.2
    NM_115221.4
    NM_180365.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables GTPase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in plasma membrane HDA PubMed 

    General protein information

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    Preferred Names
    RAB GTPase homolog 8
    NP_001078278.1
    • RAB GTPase homolog 8 (RAB8); FUNCTIONS IN: GTP binding; INVOLVED IN: protein transport, small GTPase mediated signal transduction; LOCATED IN: plasma membrane; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Ras GTPase (InterPro:IPR001806), Small GTP-binding protein (InterPro:IPR005225), Small GTPase (InterPro:IPR020851), Ras (InterPro:IPR013753), Ras small GTPase, Rab type (InterPro:IPR003579); BEST Arabidopsis thaliana protein match is: Ras-related small GTP-binding family protein (TAIR:AT5G59840.1); Has 29736 Blast hits to 29676 proteins in 811 species: Archae - 22; Bacteria - 184; Metazoa - 15446; Fungi - 4267; Plants - 3567; Viruses - 20; Other Eukaryotes - 6230 (source: NCBI BLink).
    NP_190929.1
    • RAB GTPase homolog 8 (RAB8); FUNCTIONS IN: GTP binding; INVOLVED IN: protein transport, small GTPase mediated signal transduction; LOCATED IN: plasma membrane; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Ras GTPase (InterPro:IPR001806), Small GTP-binding protein (InterPro:IPR005225), Small GTPase (InterPro:IPR020851), Ras (InterPro:IPR013753), Ras small GTPase, Rab type (InterPro:IPR003579); BEST Arabidopsis thaliana protein match is: Ras-related small GTP-binding family protein (TAIR:AT5G59840.1); Has 29736 Blast hits to 29676 proteins in 811 species: Archae - 22; Bacteria - 184; Metazoa - 15446; Fungi - 4267; Plants - 3567; Viruses - 20; Other Eukaryotes - 6230 (source: NCBI BLink).
    NP_850696.1
    • RAB GTPase homolog 8 (RAB8); FUNCTIONS IN: GTP binding; INVOLVED IN: protein transport, small GTPase mediated signal transduction; LOCATED IN: plasma membrane; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Ras GTPase (InterPro:IPR001806), Small GTP-binding protein (InterPro:IPR005225), Small GTPase (InterPro:IPR020851), Ras (InterPro:IPR013753), Ras small GTPase, Rab type (InterPro:IPR003579); BEST Arabidopsis thaliana protein match is: Ras-related small GTP-binding family protein (TAIR:AT5G59840.1); Has 29736 Blast hits to 29676 proteins in 811 species: Archae - 22; Bacteria - 184; Metazoa - 15446; Fungi - 4267; Plants - 3567; Viruses - 20; Other Eukaryotes - 6230 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      19876232..19878792 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_115221.4 → NP_190929.1  RAB GTPase homolog 8 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_190929.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O24466
      UniProtKB/TrEMBL
      A0A178V8G1, A0A5S9XKH5, A0A654FFH5
      Conserved Domains (1) summary
      cd01867
      Location:13 → 180
      Rab8_Rab10_Rab13_like; Rab GTPase families 8, 10, 13 (Rab8, Rab10, Rab13)

    2. NM_001084809.2 → NP_001078278.1  RAB GTPase homolog 8 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001078278.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O24466
      UniProtKB/TrEMBL
      A0A178V8G1, A0A5S9XKH5, A0A654FFH5
      Conserved Domains (1) summary
      cd01867
      Location:13 → 180
      Rab8_Rab10_Rab13_like; Rab GTPase families 8, 10, 13 (Rab8, Rab10, Rab13)

    3. NM_180365.3 → NP_850696.1  RAB GTPase homolog 8 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_850696.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O24466
      UniProtKB/TrEMBL
      A0A178V8G1, A0A5S9XKH5, A0A654FFH5
      Conserved Domains (1) summary
      cd01867
      Location:13 → 180
      Rab8_Rab10_Rab13_like; Rab GTPase families 8, 10, 13 (Rab8, Rab10, Rab13)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O24466.1

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