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    LPPepsilon1 Phosphatidic acid phosphatase (PAP2) family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 824256, updated on 18-Sep-2024

    Summary

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    Official Symbol
    LPPepsilon1
    Official Full Name
    Phosphatidic acid phosphatase (PAP2) family protein
    Primary source
    TAIR:AT3G50920
    Locus tag
    AT3G50920
    See related
    Araport:AT3G50920
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    lipid phosphate phosphatase epsilon 1
    Summary
    Encodes a phosphatidic acid phosphatase that can be detected in chloroplast membrane fractions. This gene (LPPepsilon1) and LPPepsilon2, appear to be less important for diacylglycerol formation in the plastids than LPPgamma.
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    Genomic context

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    See LPPepsilon1 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    5
    Sequence:
    Chromosome: 3; NC_003074.8 (18922304..18923772, complement)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene netrin receptor DCC Neighboring gene Defensin-like (DEFL) family protein Neighboring gene cytochrome BC1 synthesi

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Chloroplast phosphatases LPPγ and LPPε1 facilitate conversion of extraplastidic phospholipids to galactolipids. Cook R, et al. Plant Physiol, 2024 May 31. PMID 38401529
    2. Plastidic phosphatidic acid phosphatases identified in a distinct subfamily of lipid phosphate phosphatases with prokaryotic origin. Nakamura Y, et al. J Biol Chem, 2007 Sep 28. PMID 17652095
    3. Evidence for network evolution in an Arabidopsis interactome map. Arabidopsis Interactome Mapping Consortium. Science, 2011 Jul 29. PMID 21798944, Free PMC Article
    4. Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana. Salanoubat M, et al. Nature, 2000 Dec 14. PMID 11130713

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Chloroplast phosphatases LPPgamma and LPPepsilon1 facilitate conversion of extraplastidic phospholipids to galactolipids.
      Title: Chloroplast phosphatases LPPγ and LPPε1 facilitate conversion of extraplastidic phospholipids to galactolipids.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_001035758.3
    NM_114952.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables phosphatidate phosphatase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within diacylglycerol biosynthetic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Phosphatidic acid phosphatase (PAP2) family protein
    NP_001030835.1
    • Phosphatidic acid phosphatase (PAP2) family protein; FUNCTIONS IN: catalytic activity; INVOLVED IN: biological_process unknown; LOCATED IN: membrane; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Phosphatidic acid phosphatase type 2/haloperoxidase (InterPro:IPR000326); BEST Arabidopsis thaliana protein match is: Phosphatidic acid phosphatase (PAP2) family protein (TAIR:AT5G66450.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).
    NP_190661.2
    • Phosphatidic acid phosphatase (PAP2) family protein; FUNCTIONS IN: catalytic activity; INVOLVED IN: biological_process unknown; LOCATED IN: chloroplast, membrane; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Phosphatidic acid phosphatase type 2/haloperoxidase (InterPro:IPR000326); BEST Arabidopsis thaliana protein match is: Phosphatidic acid phosphatase (PAP2) family protein (TAIR:AT5G66450.1); Has 367 Blast hits to 367 proteins in 161 species: Archae - 0; Bacteria - 52; Metazoa - 96; Fungi - 101; Plants - 80; Viruses - 0; Other Eukaryotes - 38 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      18922304..18923772 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001035758.3 → NP_001030835.1  Phosphatidic acid phosphatase (PAP2) family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001030835.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A7G2EQD4
      Conserved Domains (2) summary
      COG0671
      Location:56 → 198
      PgpB; Membrane-associated phospholipid phosphatase [Lipid transport and metabolism]
      cd03382
      Location:49 → 183
      PAP2_dolichyldiphosphatase; PAP2_like proteins, dolichyldiphosphatase subfamily. Dolichyldiphosphatase is a membrane-associated protein located in the endoplasmic reticulum and hydrolyzes dolichyl pyrophosphate, as well as dolichylmonophosphate at a low rate. The enzyme is ...

    2. NM_114952.4 → NP_190661.2  Phosphatidic acid phosphatase (PAP2) family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_190661.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      F4J220, Q9SVK7
      UniProtKB/TrEMBL
      A0A5S9XKF4, A0A654FEQ1
      Conserved Domains (1) summary
      cd03382
      Location:100 → 234
      PAP2_dolichyldiphosphatase; PAP2_like proteins, dolichyldiphosphatase subfamily. Dolichyldiphosphatase is a membrane-associated protein located in the endoplasmic reticulum and hydrolyzes dolichyl pyrophosphate, as well as dolichylmonophosphate at a low rate. The enzyme is ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    F4J220.1

    Gene LinkOut

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