U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination
    • Showing Current items.

    DAD1 alpha/beta-Hydrolases superfamily protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 819090, updated on 18-Sep-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    DAD1
    Official Full Name
    alpha/beta-Hydrolases superfamily protein
    Primary source
    TAIR:AT2G44810
    Locus tag
    AT2G44810
    See related
    Araport:AT2G44810
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    DEFECTIVE ANTHER DEHISCENCE 1; F16B22.45
    Summary
    Mutant has defects in anther dehiscence, pollen maturation, and flower opening. The DAD1 protein is a chloroplastic phospholipase A1 that catalyzes the initial step of jasmonic acid biosynthesis.
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See DAD1 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    1
    Sequence:
    Chromosome: 2; NC_003071.7 (18478374..18480457)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene 2-oxoglutarate (2OG) and Fe(II)-dependent oxygenase superfamily protein Neighboring gene axoneme-associated protein MST101(2) protein Neighboring gene Protein kinase superfamily protein

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. The DEFECTIVE IN ANTHER DEHISCIENCE gene encodes a novel phospholipase A1 catalyzing the initial step of jasmonic acid biosynthesis, which synchronizes pollen maturation, anther dehiscence, and flower opening in Arabidopsis. Ishiguro S, et al. Plant Cell, 2001 Oct. PMID 11595796, Free PMC Article
    2. DONGLE and DEFECTIVE IN ANTHER DEHISCENCE1 lipases are not essential for wound- and pathogen-induced jasmonate biosynthesis: redundant lipases contribute to jasmonate formation. Ellinger D, et al. Plant Physiol, 2010 May. PMID 20348210, Free PMC Article
    3. Cooperation and functional diversification of two closely related galactolipase genes for jasmonate biosynthesis. Hyun Y, et al. Dev Cell, 2008 Feb. PMID 18267087
    4. Wound-induced expression of DEFECTIVE IN ANTHER DEHISCENCE1 and DAD1-like lipase genes is mediated by both CORONATINE INSENSITIVE1-dependent and independent pathways in Arabidopsis thaliana. Ruduś I, et al. Plant Cell Rep, 2014 Jun. PMID 24430866
    5. OXI1 and DAD Regulate Light-Induced Cell Death Antagonistically through Jasmonate and Salicylate Levels. Beaugelin I, et al. Plant Physiol, 2019 Jul. PMID 31123095, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The expression of DAD1, DGL, and other DAD1-LIKE LIPASE (DALL) genes is induced upon wounding. DAD1 and DGL required COI1 for their expression, suggesting that a molecule other than jasmonic acid (JA) might act as a regulator of COI1.
      Title: Wound-induced expression of DEFECTIVE IN ANTHER DEHISCENCE1 and DAD1-like lipase genes is mediated by both CORONATINE INSENSITIVE1-dependent and independent pathways in Arabidopsis thaliana.
    2. participates in jasmonate formation only in the late wound response
      Title: DONGLE and DEFECTIVE IN ANTHER DEHISCENCE1 lipases are not essential for wound- and pathogen-induced jasmonate biosynthesis: redundant lipases contribute to jasmonate formation.
    Submit: New GeneRIF Correction

    Pathways from PubChem

    Go to the top of the page

    General gene information

    Go to the top of the page Help

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables galactolipase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables phosphatidylserine 1-acylhydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables phospholipase A1 activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables phospholipase A1 activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within anther dehiscence IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within jasmonic acid biosynthetic process IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within jasmonic acid biosynthetic process TAS
    Traceable Author Statement
    more info
    		 PubMed 
    acts_upstream_of_or_within pollen maturation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within positive regulation of programmed cell death IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within response to wounding IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytoplasm TAS
    Traceable Author Statement
    more info
    		 PubMed 
    located_in extracellular region ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    alpha/beta-Hydrolases superfamily protein
    NP_182008.1
    • DEFECTIVE ANTHER DEHISCENCE 1 (DAD1); CONTAINS InterPro DOMAIN/s: Lipase, class 3 (InterPro:IPR002921); BEST Arabidopsis thaliana protein match is: alpha/beta-Hydrolases superfamily protein (TAIR:AT4G16820.1); Has 1715 Blast hits to 1709 proteins in 324 species: Archae - 0; Bacteria - 331; Metazoa - 67; Fungi - 376; Plants - 633; Viruses - 9; Other Eukaryotes - 299 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      18478374..18480457
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001337097.1 → NP_001324613.1  alpha/beta-Hydrolases superfamily protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      F4IV22, O22170, Q948R1
      UniProtKB/TrEMBL
      A0A178VZL3, A0A5S9X716

    2. NM_130045.4 → NP_182008.1  alpha/beta-Hydrolases superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_182008.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q948R1
      Conserved Domains (1) summary
      PLN02408
      Location:1 → 357
      PLN02408; phospholipase A1
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q948R1.1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.