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    protein kinase family protein / protein phosphatase 2C (PP2C) family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 818684, updated on 18-Sep-2024

    Summary

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    Official Full Name
    protein kinase family protein / protein phosphatase 2C (PP2C) family protein
    Primary source
    TAIR:AT2G40860
    Locus tag
    AT2G40860
    See related
    Araport:AT2G40860
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    T20B5.6; T20B5_6
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    Genomic context

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    Location:
    chromosome: 2
    Exon count:
    13
    Sequence:
    Chromosome: 2; NC_003071.7 (17053498..17057326, complement)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene RING-H2 finger C1A Neighboring gene disproportionating enzyme 2 Neighboring gene phosphoinositide 4-kinase gamma 1 Neighboring gene cytochrome P450, family 98, subfamily A, polypeptide 3 Neighboring gene cystatin A Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Identification of Arabidopsis VTC3 as a putative and unique dual function protein kinase::protein phosphatase involved in the regulation of the ascorbic acid pool in plants. Conklin PL, et al. J Exp Bot, 2013 Jul. PMID 23749562
    2. Identification of ascorbic acid-deficient Arabidopsis thaliana mutants. Conklin PL, et al. Genetics, 2000 Feb. PMID 10655235, Free PMC Article
    3. Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana. Lin X, et al. Nature, 1999 Dec 16. PMID 10617197

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. VTC3(AT2G40860} is a dual function protein kinase::protein phosphatase involved in the regulation of the ascorbic acid.
      Title: Identification of Arabidopsis VTC3 as a putative and unique dual function protein kinase::protein phosphatase involved in the regulation of the ascorbic acid pool in plants.
    Submit: New GeneRIF Correction

    General gene information

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    NM_001336874.1
    NM_001336875.1
    NM_180005.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables myosin phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein serine/threonine phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within L-ascorbic acid metabolic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    protein kinase family protein / protein phosphatase 2C (PP2C) family protein
    NP_850336.1
    • protein kinase family protein / protein phosphatase 2C (PP2C) family protein; FUNCTIONS IN: protein serine/threonine kinase activity, protein serine/threonine phosphatase activity, protein kinase activity, catalytic activity, ATP binding; INVOLVED IN: protein amino acid phosphorylation; LOCATED IN: cellular_component unknown; EXPRESSED IN: 14 plant structures; EXPRESSED DURING: 6 growth stages; CONTAINS InterPro DOMAIN/s: Protein kinase, catalytic domain (InterPro:IPR000719), Protein phosphatase 2C-related (InterPro:IPR001932), Protein phosphatase 2C, N-terminal (InterPro:IPR014045), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271); BEST Arabidopsis thaliana protein match is: HOPW1-1-interacting 2 (TAIR:AT4G31750.1); Has 131448 Blast hits to 130118 proteins in 4510 species: Archae - 166; Bacteria - 15372; Metazoa - 47633; Fungi - 11848; Plants - 35207; Viruses - 642; Other Eukaryotes - 20580 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      17053498..17057326 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001336873.1 → NP_001325403.1  protein kinase family protein / protein phosphatase 2C (PP2C) family protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8B344, A0A5S9X6E3

    2. NM_180005.4 → NP_850336.1  protein kinase family protein / protein phosphatase 2C (PP2C) family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_850336.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O22200, O22201, Q940A2
      UniProtKB/TrEMBL
      A0A5S9X6E3
      Conserved Domains (3) summary
      smart00220
      Location:30 → 307
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd00143
      Location:391 → 648
      PP2Cc; Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence ...
      cl21453
      Location:36 → 311
      PKc_like; Protein Kinases, catalytic domain

    3. NM_001336874.1 → NP_001325402.1  protein kinase family protein / protein phosphatase 2C (PP2C) family protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8B342, A0A5S9X6E3

    4. NM_001336875.1 → NP_001325404.1  protein kinase family protein / protein phosphatase 2C (PP2C) family protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8B331, A0A5S9X6E3
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q940A2.1

    Gene LinkOut

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