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    HTA8 histone H2A 8 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 818463, updated on 18-Sep-2024

    Summary

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    Official Symbol
    HTA8
    Official Full Name
    histone H2A 8
    Primary source
    TAIR:AT2G38810
    Locus tag
    AT2G38810
    See related
    Araport:AT2G38810
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F13I13.4; F13I13_4; histone H2A 8
    Summary
    Encodes HTA8, a histone H2A protein. Loss of all H2A.Z (triple mutant with HTA9 and HTA11) results in a reduction in DNA methylation of transposons but not that of genes. Loss of H2A.Z causes misregulation of many genes involved in the response to developmental and environmental cues, and that these genes tend to have high levels of gene-body H2A.Z.
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    Genomic context

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    See HTA8 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    4
    Sequence:
    Chromosome: 2; NC_003071.7 (16219220..16220928, complement)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene cytochrome C oxidase subunit Neighboring gene uncharacterized protein Neighboring gene Plant calmodulin-binding protein-like protein Neighboring gene DNA-directed RNA polymerase subunit beta-beta protein, putative (DUF506) Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Deposition of histone variant H2A.Z within gene bodies regulates responsive genes. Coleman-Derr D, et al. PLoS Genet, 2012. PMID 23071449, Free PMC Article
    2. Histone H2A.Z and homologues of components of the SWR1 complex are required to control immunity in Arabidopsis. March-Díaz R, et al. Plant J, 2008 Feb. PMID 17988222
    3. Arabidopsis homologs of components of the SWR1 complex regulate flowering and plant development. Choi K, et al. Development, 2007 May. PMID 17470967
    4. Proteomic analysis of the Arabidopsis nucleolus suggests novel nucleolar functions. Pendle AF, et al. Mol Biol Cell, 2005 Jan. PMID 15496452, Free PMC Article
    5. Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana. Lin X, et al. Nature, 1999 Dec 16. PMID 10617197

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_001336738.1
    NM_129438.2
    NM_179967.2
    NM_179968.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein heterodimerization activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables structural constituent of chromatin IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within regulation of flower development IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within regulation of gene expression IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleolus HDA PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    histone H2A 8
    NP_001318377.1
    • histone H2A 8 (HTA8); FUNCTIONS IN: DNA binding; INVOLVED IN: regulation of flower development; LOCATED IN: nucleolus; EXPRESSED IN: 21 plant structures; EXPRESSED DURING: 12 growth stages; CONTAINS InterPro DOMAIN/s: Histone H2A (InterPro:IPR002119), Histone-fold (InterPro:IPR009072), Histone core (InterPro:IPR007125); BEST Arabidopsis thaliana protein match is: histone H2A 11 (TAIR:AT3G54560.1); Has 3864 Blast hits to 3859 proteins in 325 species: Archae - 0; Bacteria - 0; Metazoa - 2527; Fungi - 294; Plants - 612; Viruses - 2; Other Eukaryotes - 429 (source: NCBI BLink).
    NP_181415.1
    • histone H2A 8 (HTA8); FUNCTIONS IN: DNA binding; INVOLVED IN: regulation of flower development; LOCATED IN: nucleolus; EXPRESSED IN: 21 plant structures; EXPRESSED DURING: 12 growth stages; CONTAINS InterPro DOMAIN/s: Histone H2A (InterPro:IPR002119), Histone-fold (InterPro:IPR009072), Histone core (InterPro:IPR007125); BEST Arabidopsis thaliana protein match is: histone H2A 11 (TAIR:AT3G54560.1); Has 3864 Blast hits to 3859 proteins in 325 species: Archae - 0; Bacteria - 0; Metazoa - 2527; Fungi - 294; Plants - 612; Viruses - 2; Other Eukaryotes - 429 (source: NCBI BLink).
    NP_850299.1
    • histone H2A 8 (HTA8); FUNCTIONS IN: DNA binding; INVOLVED IN: regulation of flower development; LOCATED IN: nucleolus; EXPRESSED IN: 21 plant structures; EXPRESSED DURING: 12 growth stages; CONTAINS InterPro DOMAIN/s: Histone H2A (InterPro:IPR002119), Histone-fold (InterPro:IPR009072), Histone core (InterPro:IPR007125); BEST Arabidopsis thaliana protein match is: histone H2A 11 (TAIR:AT3G54560.1); Has 3868 Blast hits to 3863 proteins in 325 species: Archae - 0; Bacteria - 0; Metazoa - 2531; Fungi - 294; Plants - 612; Viruses - 2; Other Eukaryotes - 429 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      16219220..16220928 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_179968.3 → NP_850299.1  histone H2A 8 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_850299.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9SII0
      UniProtKB/TrEMBL
      A0A178W033, A0A384KDC8, Q0WRN0
      Conserved Domains (1) summary
      PLN00154
      Location:1 → 136
      PLN00154; histone H2A; Provisional

    2. NM_179967.2 → NP_850298.1  histone H2A 8 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_850298.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9SII0
      UniProtKB/TrEMBL
      A0A178W033, A0A384KDC8, Q0WRN0
      Conserved Domains (1) summary
      PLN00154
      Location:1 → 136
      PLN00154; histone H2A; Provisional

    3. NM_001336738.1 → NP_001318377.1  histone H2A 8 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9SII0
      UniProtKB/TrEMBL
      A0A178W033, A0A384KDC8, Q0WRN0
      Conserved Domains (1) summary
      PLN00154
      Location:1 → 136
      PLN00154; histone H2A; Provisional

    4. NM_129438.2 → NP_181415.1  histone H2A 8 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_181415.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9SII0
      UniProtKB/TrEMBL
      A0A178W033, A0A384KDC8, Q0WRN0
      Conserved Domains (1) summary
      PLN00154
      Location:1 → 136
      PLN00154; histone H2A; Provisional
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9SII0.1

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