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    brd8 bromodomain containing 8 [ Xenopus tropicalis (tropical clawed frog) ]

    Gene ID: 779589, updated on 4-Jan-2025

    Summary

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    Official Symbol
    brd8provided by Xenbase
    Official Full Name
    bromodomain containing 8provided by Xenbase
    Primary source
    Xenbase:XB-GENE-967261
    See related
    Ensembl:ENSXETG00000006726 AllianceGenome:Xenbase:XB-GENE-967261
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Xenopus tropicalis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
    Summary
    Predicted to be part of NuA4 histone acetyltransferase complex. Orthologous to human BRD8 (bromodomain containing 8). [provided by Alliance of Genome Resources, Jan 2025]
    Orthologs
    human mouse all
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    Genomic context

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    See brd8 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    22
    Annotation release Status Assembly Chr Location
    104 current UCB_Xtro_10.0 (GCF_000004195.4) 3 NC_030679.2 (47816458..47841572, complement)
    103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) 3 NC_030679.1 (38319596..38341587, complement)

    Chromosome 3 - NC_030679.2Genomic Context describing neighboring genes Neighboring gene NEDD4 binding protein 3 Neighboring gene NHP2 ribonucleoprotein Neighboring gene kinesin family member 20A Neighboring gene cell division cycle 23

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by Xenbase

    Component Evidence Code Pubs
    part_of NuA4 histone acetyltransferase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    bromodomain-containing protein 8

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference UCB_Xtro_10.0 Primary Assembly

    Genomic

    1. NC_030679.2 Reference UCB_Xtro_10.0 Primary Assembly

      Range
      47816458..47841572 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_004912878.4 → XP_004912935.1  bromodomain-containing protein 8 isoform X8

      UniProtKB/TrEMBL
      A0A803JJL1, A0A8J0R2A5
      Conserved Domains (1) summary
      cd05507
      Location:669 → 772
      Bromo_brd8_like; Bromodomain, brd8_like subgroup. In mammals, brd8 (bromodomain containing 8) interacts with the thyroid hormone receptor in a ligand-dependent fashion and enhances thyroid hormone-dependent activation from thyroid response elements. Brd8 is thought to be ...

    2. XM_004912877.4 → XP_004912934.1  bromodomain-containing protein 8 isoform X9

      UniProtKB/TrEMBL
      A0A803JKB2, A0A8J0R2P2
      Related
      ENSXETP00000108349.1, ENSXETT00000117552.1
      Conserved Domains (1) summary
      cd05507
      Location:727 → 830
      Bromo_brd8_like; Bromodomain, brd8_like subgroup. In mammals, brd8 (bromodomain containing 8) interacts with the thyroid hormone receptor in a ligand-dependent fashion and enhances thyroid hormone-dependent activation from thyroid response elements. Brd8 is thought to be ...

    3. XM_004912875.4 → XP_004912932.1  bromodomain-containing protein 8 isoform X2

      UniProtKB/TrEMBL
      A0A803JKB2, F6X1Y3
      Related
      ENSXETP00000014703.5, ENSXETT00000014703.5
      Conserved Domains (1) summary
      cd05507
      Location:765 → 868
      Bromo_brd8_like; Bromodomain, brd8_like subgroup. In mammals, brd8 (bromodomain containing 8) interacts with the thyroid hormone receptor in a ligand-dependent fashion and enhances thyroid hormone-dependent activation from thyroid response elements. Brd8 is thought to be ...

    4. XM_018092218.2 → XP_017947707.1  bromodomain-containing protein 8 isoform X7

      UniProtKB/TrEMBL
      A0A8J0T167, Q05AZ6
      Conserved Domains (1) summary
      cd05507
      Location:596 → 699
      Bromo_brd8_like; Bromodomain, brd8_like subgroup. In mammals, brd8 (bromodomain containing 8) interacts with the thyroid hormone receptor in a ligand-dependent fashion and enhances thyroid hormone-dependent activation from thyroid response elements. Brd8 is thought to be ...

    5. XM_018092217.2 → XP_017947706.1  bromodomain-containing protein 8 isoform X6

      UniProtKB/TrEMBL
      A0A803J445, Q05AZ6
      Related
      ENSXETP00000102597.1, ENSXETT00000117733.1

    6. XM_012959840.3 → XP_012815294.1  bromodomain-containing protein 8 isoform X5

      UniProtKB/TrEMBL
      A0A6I8PTP1, A0A8J0SJP7
      Conserved Domains (1) summary
      cd05507
      Location:669 → 772
      Bromo_brd8_like; Bromodomain, brd8_like subgroup. In mammals, brd8 (bromodomain containing 8) interacts with the thyroid hormone receptor in a ligand-dependent fashion and enhances thyroid hormone-dependent activation from thyroid response elements. Brd8 is thought to be ...

    7. XM_012959838.3 → XP_012815292.1  bromodomain-containing protein 8 isoform X3

      UniProtKB/TrEMBL
      A0A6I8PTP1, A0A8J0SJN9
      Related
      ENSXETP00000095064.2, ENSXETT00000089562.2
      Conserved Domains (1) summary
      cd05507
      Location:727 → 830
      Bromo_brd8_like; Bromodomain, brd8_like subgroup. In mammals, brd8 (bromodomain containing 8) interacts with the thyroid hormone receptor in a ligand-dependent fashion and enhances thyroid hormone-dependent activation from thyroid response elements. Brd8 is thought to be ...

    8. XM_012959839.3 → XP_012815293.1  bromodomain-containing protein 8 isoform X4

      UniProtKB/TrEMBL
      A0A803JJL1, A0A8J0SIE9
      Related
      ENSXETP00000108128.1, ENSXETT00000121845.1
      Conserved Domains (1) summary
      cd05507
      Location:707 → 810
      Bromo_brd8_like; Bromodomain, brd8_like subgroup. In mammals, brd8 (bromodomain containing 8) interacts with the thyroid hormone receptor in a ligand-dependent fashion and enhances thyroid hormone-dependent activation from thyroid response elements. Brd8 is thought to be ...

    9. XM_002936836.5 → XP_002936882.2  bromodomain-containing protein 8 isoform X1

      UniProtKB/TrEMBL
      A0A6I8PTP1, A0A8J0QPQ7
      Conserved Domains (1) summary
      cd05507
      Location:765 → 868
      Bromo_brd8_like; Bromodomain, brd8_like subgroup. In mammals, brd8 (bromodomain containing 8) interacts with the thyroid hormone receptor in a ligand-dependent fashion and enhances thyroid hormone-dependent activation from thyroid response elements. Brd8 is thought to be ...
    Nucleotide Protein Strain
    Heading Accession and Version

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