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    silR copper/silver response regulator transcription factor SilR [ Shigella boydii ]

    Gene ID: 75205758, updated on 3-Dec-2024

    Summary

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    Gene symbol
    silR
    Gene description
    copper/silver response regulator transcription factor SilR
    Locus tag
    CEH00_RS20795
    Gene type
    protein coding
    Organism
    Shigella boydii (strain: ESBL-W3-2, nat-host: Homo sapiens)
    Lineage
    Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Shigella
    Old locus tag
    CEH00_20815
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    Genomic context

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    NZ_NIYS01000129.1Genomic Context describing neighboring genes Neighboring gene cation efflux system protein CusF Neighboring gene Cu(+)/Ag(+) efflux RND transporter outer membrane channel SilC Neighboring gene copper/silver sensor histidine kinase SilS Neighboring gene DUF305 domain-containing protein Neighboring gene silver-binding protein SilE

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NZ_NIYS01000129.1

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Transmissible silver resistance readily evolves in high-risk clone isolates of Klebsiella pneumoniae. Hanczvikkel A, et al. Acta Microbiol Immunol Hung, 2018 Aug 1. PMID 30043621
    2. Evolution of a Heavy Metal Homeostasis/Resistance Island Reflects Increasing Copper Stress in Enterobacteria. Staehlin BM, et al. Genome Biol Evol, 2016 Feb 17. PMID 26893455, Free PMC Article
    3. Silver resistance in Gram-negative bacteria: a dissection of endogenous and exogenous mechanisms. Randall CP, et al. J Antimicrob Chemother, 2015 Apr. PMID 25567964, Free PMC Article
    4. Molecular basis for resistance to silver cations in Salmonella. Gupta A, et al. Nat Med, 1999 Feb. PMID 9930866

    GeneRIFs: Gene References Into Functions

    General protein information

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    Preferred Names
    copper/silver response regulator transcription factor SilR

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NZ_NIYS01000129.1 Reference assembly

      Range
      10862..11542
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. WP_000697965.1 MULTISPECIES: copper/silver response regulator transcription factor SilR [Enterobacterales]

      See identical proteins and their annotated locations for WP_000697965.1

      UniProtKB/TrEMBL
      A0A2S1Q5W7, A0A3V3BDH2, A0A3V9J443, A0A4V0VNS8, A0A5I7B9Q9, A0A5X2VLT9, A0A5Z2T4J3, A0A625P7N2, A0A6H2GRA3, A0A9Q5TXR5, Q6EME2
      Conserved Domains (1) summary
      PRK09836
      Location:1 → 226
      PRK09836; DNA-binding transcriptional activator CusR; Provisional
    Nucleotide Protein
    Heading Accession and Version