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    polr2l.2 polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa, gene 2 [ Xenopus tropicalis (tropical clawed frog) ]

    Gene ID: 734135, updated on 9-Dec-2024

    Summary

    Official Symbol
    polr2l.2provided by Xenbase
    Official Full Name
    polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa, gene 2provided by Xenbase
    Primary source
    Xenbase:XB-GENE-5898446
    See related
    Ensembl:ENSXETG00000002878 AllianceGenome:Xenbase:XB-GENE-5898446
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Xenopus tropicalis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
    Also known as
    rbp10; rpb10; rpabc5; rpb7.6; rpb10beta
    Summary
    Predicted to enable DNA binding activity; DNA-directed 5'-3' RNA polymerase activity; and zinc ion binding activity. Predicted to act upstream of or within DNA-templated transcription. Predicted to be part of DNA-directed RNA polymerase complex. Orthologous to human POLR2L (RNA polymerase II, I and III subunit L). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See polr2l.2 in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    104 current UCB_Xtro_10.0 (GCF_000004195.4) 7 NC_030683.2 (111020957..111022263, complement)
    103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) 7 NC_030683.1 (103150660..103151958, complement)

    Chromosome 7 - NC_030683.2Genomic Context describing neighboring genes Neighboring gene insulin 1 precursor Neighboring gene BCL2-like 12 (proline rich) Neighboring gene protein arginine methyltransferase 1 Neighboring gene tetraspanin 4 Neighboring gene extensin-like

    Genomic regions, transcripts, and products

    General gene information

    Clone Names

    • MGC121801

    Gene Ontology Provided by Xenbase

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables DNA-directed 5'-3' RNA polymerase activity IEA
    Inferred from Electronic Annotation
    more info
     
    contributes_to RNA polymerase I activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    contributes_to RNA polymerase II activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    contributes_to RNA polymerase III activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables zinc ion binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in tRNA transcription by RNA polymerase III IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in transcription by RNA polymerase I IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    part_of DNA-directed RNA polymerase complex IEA
    Inferred from Electronic Annotation
    more info
     
    part_of RNA polymerase I complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of RNA polymerase II, core complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of RNA polymerase III complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa, gene 2
    Names
    polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001171594.1NP_001165065.1  polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa, gene 2

      See identical proteins and their annotated locations for NP_001165065.1

      Status: PROVISIONAL

      Source sequence(s)
      BC135758
      UniProtKB/TrEMBL
      F7CZ47, Q1ECU1
      Conserved Domains (1) summary
      pfam01194
      Location:159
      RNA_pol_N; RNA polymerases N / 8 kDa subunit

    RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference UCB_Xtro_10.0 Primary Assembly

    Genomic

    1. NC_030683.2 Reference UCB_Xtro_10.0 Primary Assembly

      Range
      111020957..111022263 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_012966715.2XP_012822169.1  polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa, gene 2 isoform X1

      See identical proteins and their annotated locations for XP_012822169.1

      UniProtKB/TrEMBL
      F7CZ47, Q1ECU1
      Related
      ENSXETP00000006290.3, ENSXETT00000006290.5
      Conserved Domains (1) summary
      pfam01194
      Location:159
      RNA_pol_N; RNA polymerases N / 8 kDa subunit