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    Dnajc22 DnaJ heat shock protein family (Hsp40) member C22 [ Mus musculus (house mouse) ]

    Gene ID: 72778, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Dnajc22provided by MGI
    Official Full Name
    DnaJ heat shock protein family (Hsp40) member C22provided by MGI
    Primary source
    MGI:MGI:1920028
    See related
    Ensembl:ENSMUSG00000038009 AllianceGenome:MGI:1920028
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    2810451A06Rik
    Summary
    Predicted to be active in membrane. Is expressed in brain; gut; liver lobe; and metanephros. Orthologous to human DNAJC22 (DnaJ heat shock protein family (Hsp40) member C22). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in liver adult (RPKM 41.6), large intestine adult (RPKM 20.1) and 9 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Dnajc22 in Genome Data Viewer
    Location:
    15 F1; 15 55.87 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (98991102..99002618)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (99099134..99104709)

    Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene trophinin associated protein Neighboring gene microRNA 6960 Neighboring gene complement component 1, q subcomponent-like 4 Neighboring gene spermatogenesis associated, serine-rich 2 Neighboring gene predicted gene, 57817 Neighboring gene predicted gene, 25183 Neighboring gene STARR-seq mESC enhancer starr_39699 Neighboring gene predicted gene, 46538 Neighboring gene potassium voltage-gated channel, subfamily H (eag-related), member 3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Wurst is essential for airway clearance and respiratory-tube size control. Behr M, et al. Nat Cell Biol, 2007 Jul. PMID 17558392
    2. Identification of transcripts with enriched expression in the developing and adult pancreas. Hoffman BG, et al. Genome Biol, 2008. PMID 18554416, Free PMC Article
    3. Database resources of the National Center for Biotechnology Information. Wheeler DL, et al. Nucleic Acids Res, 2001 Jan 1. PMID 11125038, Free PMC Article
    4. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article
    5. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article

    See all (15) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Component Evidence Code Pubs
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    dnaJ homolog subfamily C member 22
    Names
    DnaJ (Hsp40) homolog, subfamily B, member 3; heat shock protein, DNAJ-like 3
    DnaJ (Hsp40) homolog, subfamily C, member 22

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001418805.1 → NP_001405734.1  dnaJ homolog subfamily C member 22

      Status: VALIDATED

      Source sequence(s)
      AC157610
      UniProtKB/Swiss-Prot
      Q8CHS2

    2. NM_001418806.1 → NP_001405735.1  dnaJ homolog subfamily C member 22

      Status: VALIDATED

      Source sequence(s)
      AC157610
      UniProtKB/Swiss-Prot
      Q8CHS2

    3. NM_176835.3 → NP_789805.1  dnaJ homolog subfamily C member 22

      See identical proteins and their annotated locations for NP_789805.1

      Status: VALIDATED

      Source sequence(s)
      AC157610
      Consensus CDS
      CCDS27815.1
      UniProtKB/Swiss-Prot
      Q8CHS2
      Related
      ENSMUSP00000055482.7, ENSMUST00000061295.7
      Conserved Domains (1) summary
      smart00271
      Location:278 → 335
      DnaJ; DnaJ molecular chaperone homology domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000081.7 Reference GRCm39 C57BL/6J

      Range
      98991102..99002618
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006521457.5 → XP_006521520.1  dnaJ homolog subfamily C member 22 isoform X1

      See identical proteins and their annotated locations for XP_006521520.1

      UniProtKB/Swiss-Prot
      Q8CHS2
      Conserved Domains (1) summary
      smart00271
      Location:278 → 335
      DnaJ; DnaJ molecular chaperone homology domain
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8CHS2.1 GenPept UniProtKB/Swiss-Prot:Q8CHS2

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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