RGL3 ral guanine nucleotide dissociation stimulator like 3 [Macaca mulatta (Rhesus monkey)] - Gene

Summary

Official Symbol: RGL3provided by VGNC
Official Full Name: ral guanine nucleotide dissociation stimulator like 3provided by VGNC
Primary source: VGNC:VGNC:76869
See related: Ensembl:ENSMMUG00000010826
Gene type: protein coding
RefSeq status: MODEL
Organism: Macaca mulatta
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 19

Exon count:: 20

Annotation release	Status	Assembly	Chr	Location
103	current	Mmul_10 (GCF_003339765.1)	19	NC_041772.1 (11150603..11176444, complement)
102	previous assembly	Mmul_8.0.1 (GCF_000772875.2)	19	NC_027911.1 (11429862..11455174, complement)

Chromosome 19 - NC_041772.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

SHGC-110871 (e-PCR)
- UniSTS:168058

RGL3__5490 (e-PCR)
- UniSTS:463862

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables guanyl-nucleotide exchange factor activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in Ras protein signal transduction	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of GTPase activity	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in plasma membrane	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: ral guanine nucleotide dissociation stimulator-like 3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

NC_041772.1 Reference Mmul_10 Primary Assembly

Range

11150603..11176444 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_028838757.1 → XP_028694590.1 ral guanine nucleotide dissociation stimulator-like 3 isoform X5

UniProtKB/TrEMBL

G7NL77

Conserved Domains (3) summary

cd06224
Location:74 → 196

REM; Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal domain (RasGef_N), also called REM domain (Ras exchanger motif). This domain is common in nucleotide exchange factors for Ras-like small GTPases and is typically found immediately ...

cd17212
Location:535 → 621

RA_RGL3; Ras-associating (RA) domain found in Ral guanine nucleotide dissociation stimulator-like 3 (RalGDS-like 3) and similar proteins

cl02485
Location:243 → 413

RasGEF; Guanine nucleotide exchange factor for Ras-like small GTPases. Small GTP-binding proteins of the Ras superfamily function as molecular switches in fundamental events such as signal transduction, cytoskeleton dynamics and intracellular trafficking. ...
XM_028838756.1 → XP_028694589.1 ral guanine nucleotide dissociation stimulator-like 3 isoform X4

UniProtKB/TrEMBL

G7NL77

Conserved Domains (3) summary

cd06224
Location:74 → 196

REM; Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal domain (RasGef_N), also called REM domain (Ras exchanger motif). This domain is common in nucleotide exchange factors for Ras-like small GTPases and is typically found immediately ...

cd17212
Location:564 → 650

RA_RGL3; Ras-associating (RA) domain found in Ral guanine nucleotide dissociation stimulator-like 3 (RalGDS-like 3) and similar proteins

cl02485
Location:243 → 442

RasGEF; Guanine nucleotide exchange factor for Ras-like small GTPases. Small GTP-binding proteins of the Ras superfamily function as molecular switches in fundamental events such as signal transduction, cytoskeleton dynamics and intracellular trafficking. ...
XM_028838755.1 → XP_028694588.1 ral guanine nucleotide dissociation stimulator-like 3 isoform X3

UniProtKB/TrEMBL

G7NL77

Conserved Domains (3) summary

cd06224
Location:74 → 196

REM; Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal domain (RasGef_N), also called REM domain (Ras exchanger motif). This domain is common in nucleotide exchange factors for Ras-like small GTPases and is typically found immediately ...

smart00147
Location:243 → 476

RasGEF; Guanine nucleotide exchange factor for Ras-like small GTPases

cd17212
Location:598 → 684

RA_RGL3; Ras-associating (RA) domain found in Ral guanine nucleotide dissociation stimulator-like 3 (RalGDS-like 3) and similar proteins
XM_028838754.1 → XP_028694587.1 ral guanine nucleotide dissociation stimulator-like 3 isoform X1

UniProtKB/TrEMBL

G7NL77

Conserved Domains (3) summary

cd06224
Location:74 → 196

REM; Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal domain (RasGef_N), also called REM domain (Ras exchanger motif). This domain is common in nucleotide exchange factors for Ras-like small GTPases and is typically found immediately ...

smart00147
Location:243 → 505

RasGEF; Guanine nucleotide exchange factor for Ras-like small GTPases

cd17212
Location:627 → 713

RA_RGL3; Ras-associating (RA) domain found in Ral guanine nucleotide dissociation stimulator-like 3 (RalGDS-like 3) and similar proteins
XM_001105342.3 → XP_001105342.2 ral guanine nucleotide dissociation stimulator-like 3 isoform X2

UniProtKB/TrEMBL

F6XC79, F7GNX9

Related

ENSMMUP00000014194.4, ENSMMUT00000015146.4

Conserved Domains (3) summary

cd06224
Location:74 → 196

REM; Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal domain (RasGef_N), also called REM domain (Ras exchanger motif). This domain is common in nucleotide exchange factors for Ras-like small GTPases and is typically found immediately ...

smart00147
Location:243 → 505

RasGEF; Guanine nucleotide exchange factor for Ras-like small GTPases

cd17212
Location:610 → 696

RA_RGL3; Ras-associating (RA) domain found in Ral guanine nucleotide dissociation stimulator-like 3 (RalGDS-like 3) and similar proteins
XM_028838758.1 → XP_028694591.1 ral guanine nucleotide dissociation stimulator-like 3 isoform X6

UniProtKB/TrEMBL

F6XC79

Conserved Domains (3) summary

smart00147
Location:127 → 389

RasGEF; Guanine nucleotide exchange factor for Ras-like small GTPases

cd17212
Location:511 → 597

RA_RGL3; Ras-associating (RA) domain found in Ral guanine nucleotide dissociation stimulator-like 3 (RalGDS-like 3) and similar proteins

cl02520
Location:10 → 80

REM; Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal domain (RasGef_N), also called REM domain (Ras exchanger motif). This domain is common in nucleotide exchange factors for Ras-like small GTPases and is typically found immediately ...